The location of this hotel is absolutely ideal to visit the Guggenheim museum. It is maybe 2 blocks away--the only hotel closer is fantastically expensive.
We were pleasantly surprised by this hotel, which in my opinion exceeds its 2 star rating. Just to manage expectations...it is basically one floor of an apartment building. There is no breakfast on offer, because they don't have a kitchen. But there was a (very helpful) person on call at all time, and the rooms are clean and well appointed, with a nice big bathroom. I also really liked that there is a little lounge area, with a coffee machine and some comfortable places to sit.
VERY IMPORTANT...if you are planning to have a car with you, contact the hotel in advance to reserve parking. We were lucky and there was a space available (the hotel has an arrangement with a lot near the museum). But we would have been in deep trouble if a space hadn't been open. I will note that it is possible to pull up in front of the hotel, so long as you avoid the bus stop. So the parking situation is not absolutely ideal, but workable.