Calle 50

A cityscape with modern skyscrapers and lush green trees.
A cityscape with modern skyscrapers, including a distinctive twisting tower.
A modern, spiraling skyscraper with a unique design, surrounded by other buildings in an urban setting.
A harbor with several boats docked in the foreground and a city skyline in the background.
A city skyline with tall buildings and palm trees.

Tours & day trips

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City Sightseeing Panama City Hop-On Hop-Off Bus Tour

City Sightseeing Panama City Hop-On Hop-Off Bus Tour

Activity duration is 1 day
8.0 out of 10 with 174 reviews
Free cancellation available
Price is €26 per adult
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Adventure & outdoor

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All included - Day tour in San Blas Islands - No extra fees

All included - Day tour in San Blas Islands - No extra fees

Activity duration is 14 hours
2.0 out of 10 with 1 review
Free cancellation available
Price is €95 per adult
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Private & custom tours

See all 14 activities
PRIVATE NIGHT TOUR in Ciudad PANAMA + 360° POIN views

PRIVATE NIGHT TOUR in Ciudad PANAMA + 360° POIN views

Activity duration is 4 hours
10.0 out of 10 with 39 reviews
Free cancellation available
The previous price was €75 and current price is €64 per adult
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Cruises & boat tours

See all 5 activities
Panama Canal Partial Transit

Panama Canal Partial Transit

Activity duration is 7 hours
8.6 out of 10 with 104 reviews
Free cancellation available
Price is €130 per adult
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Food, drink & nightlife

See all 4 activities
E-Tickets Emotions Dinner Live Show Admission

E-Tickets Emotions Dinner Live Show Admission

Activity duration is 2 hours
9.0 out of 10 with 22 reviews
Price is €65 per adult
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Stay near popular Calle 50 attractions

Calle 50

You can find out about the history of Panama City when you stop by Calle 50. Discover the area's shops or seek out its local tours.
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Top Hotel Deals

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella Panama City Panama
Hotel Riu Plaza Panama
Megapolis Hotel Panamá

Megapolis Hotel Panamá

4.5 out of 5
Avenida Balboa Panama City
Megapolis Hotel Panamá
Courtyard by Marriott Panama Multiplaza Mall

Courtyard by Marriott Panama Multiplaza Mall

4 out of 5
Via Israel Multiplaza Pacific Mall Panama City Panama
Courtyard by Marriott Panama Multiplaza Mall
Principe Hotel and Suites

Principe Hotel and Suites

3 out of 5
Via Argentina Panama City Panama
Principe Hotel and Suites
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi Panama City
Waymore Hotel Spa & Casino
Hospedium Princess Hotel Panama

Hospedium Princess Hotel Panama

3.5 out of 5
Calle 53 Marbella y Avenida 5a B sur Panama City Panama
Hospedium Princess Hotel Panama
Waldorf Astoria Panama

Waldorf Astoria Panama

5 out of 5
47th St. & Uruguay Street Panama City Panama
Waldorf Astoria Panama
The District Hotel Panama

The District Hotel Panama

3 out of 5
C. Eusebio A. Morales Panama City Provincia de Panamá
The District Hotel Panama
The Executive Hotel

The Executive Hotel

3.5 out of 5
Calle 52 Panama City Panama
The Executive Hotel
See all 1,763 properties in Calle 50
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.