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Panama City Hotel Guide - Calle 50 hotels in Panama City, Panama.

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Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for Calle 50 hotels

A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.

1. Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Campo Alegre, 1 km from Calle 50
9.6 out of 10, Exceptional, (495 reviews)
"Enjoyed our stay"
United States
Mariah
The price is €224
includes taxes & fees
4 Nov - 5 Nov
Hyatt Regency Panama City
A covered outdoor seating area with a view of a city skyline and water.

2. Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (2,233 reviews)
"Nice place close to everything."
United States
Rene
The price is €129
includes taxes & fees
6 Nov - 7 Nov
Plaza Paitilla Inn Hotel
An outdoor patio area with tables and chairs, a pool, and a covered seating area.

3. Hostal Familiar Carmencita - Hostel

Hostal Familiar Carmencita - Hostel
2.0 star property
Bella Vista, 1.1 km from Calle 50
9.4 out of 10, Exceptional, (13 reviews)
"The manager was very nice. Close to some good restaurants."
United States
Brooke
The price is €42
includes taxes & fees
31 Oct - 1 Nov
Hostal Familiar Carmencita - Hostel
A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.

4. Gran Evenia Panama

Gran Evenia Panama
4.5 star property
El Cangrejo, 1 km from Calle 50
9.2 out of 10, Wonderful, (254 reviews)
"Had a wonderful stay, close walking food area and not too far from the mall"
United States
Johneil
The price is €98
includes taxes & fees
12 Nov - 13 Nov
Gran Evenia Panama
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.

5. Novotel Panama City

Novotel Panama City
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1,300 reviews)
"Nice place to stay."
United States
CARLOS
The price is €105
includes taxes & fees
5 Nov - 6 Nov
Novotel Panama City
A hotel named PRINCIPE with a modern facade and large glass windows.

6. Principe Hotel and Suites

Principe Hotel and Suites
3.0 star property
El Cangrejo, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (2,120 reviews)
"Very economically priced for a short comfortable stay whilst on holiday or business"
United States
Lisa
The price is €58
includes taxes & fees
1 Nov - 2 Nov
Principe Hotel and Suites
A rooftop pool area with lounge chairs and tables, surrounded by a city skyline at dusk.

7. Yoo Apartamento

Yoo Apartamento
3.0 star property
Bella Vista, 1.3 km from Calle 50
9.4 out of 10, Exceptional, (28 reviews)
"Everything was great!! Would definitely book again on my next trip to Panamá"
United States
Sheena
The price is €134
includes taxes & fees
13 Nov - 14 Nov
Yoo Apartamento
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

8. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista, 1.1 km from Calle 50
9.2 out of 10, Wonderful, (1,000 reviews)
"was good"
United States
Juliet
The price is €208
includes taxes & fees
13 Nov - 14 Nov
Bristol Panama, a Registry Collection Hotel
A poolside area with lounge chairs and a view of the ocean.

9. JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 1.5 km from Calle 50
9.2 out of 10, Wonderful, (1,001 reviews)
"Beautiful hotel, Excellent hotel with great views, very clean the food was good"
United States
GIORIA
The price is €329
includes taxes & fees
13 Nov - 14 Nov
JW Marriott Panama
A hotel entrance with a covered walkway, large windows, and a well-maintained garden area.

10. Hotel Milan

Hotel Milan
3.0 star property
El Cangrejo, 1.3 km from Calle 50
9.0 out of 10, Wonderful, (600 reviews)
"Hotel is maintained and managed well, close to many restaurants and transportation."
United States
Michael
The price is €39
includes taxes & fees
2 Nov - 3 Nov
Hotel Milan
A modern building with a sign reading "LA RESIDENCE" and a car parked in front.

11. La Résidence Panamá

La Résidence Panamá
3.5 star property
Campo Alegre, 1 km from Calle 50
9.2 out of 10, Wonderful, (21 reviews)
"Excellent rooms and fantastic staff!"
United States
Mohamad
The price is €135
includes taxes & fees
31 Oct - 1 Nov
La Résidence Panamá
A rooftop pool with sun loungers and umbrellas, surrounded by palm trees and modern buildings.

12. Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 0.7 km from Calle 50
9.0 out of 10, Wonderful, (6,142 reviews)
"Great clean hotel! Very nice location"
Canada
Sean
The price is €139
includes taxes & fees
23 Nov - 24 Nov
Hotel Riu Plaza Panama
A rooftop pool with lounge chairs and a city skyline view.

13. TRYP by Wyndham Panamá Centro

TRYP by Wyndham Panamá Centro
3.5 star property
El Cangrejo, 1.4 km from Calle 50
9.0 out of 10, Wonderful, (1,000 reviews)
"I love the tryp i was well taken care of and thank you expedia for my voucher ."
United States
Bert
The price is €88
includes taxes & fees
15 Nov - 16 Nov
TRYP by Wyndham Panamá Centro
A poolside area with lounge chairs and umbrellas, overlooking a clear blue sea and a city skyline.

14. Residence Inn by Marriott Panama City

Residence Inn by Marriott Panama City
4.0 star property
Punta Paitilla, 1 km from Calle 50
9.2 out of 10, Wonderful, (693 reviews)
"Great place!"
United States
david
The price is €194
includes taxes & fees
3 Nov - 4 Nov
Residence Inn by Marriott Panama City
An outdoor seating area with wooden tables and chairs, surrounded by potted plants and a yellow wall.

15. Panama House Bed & Breakfast

Panama House Bed & Breakfast
2.5 star property
Bella Vista, 1 km from Calle 50
9.0 out of 10, Wonderful, (233 reviews)
"Staff was courteous, room was clean."
United States
John
The price is €23
includes taxes & fees
4 Nov - 5 Nov
Panama House Bed & Breakfast
Balcony

16. San Francisco by Wynwood House

San Francisco by Wynwood House
3.0 star property
San Francisco, 1.2 km from Calle 50
9.2 out of 10, Wonderful, (66 reviews)
"Wonderful location. The staff is very friendly. I highly recommend a Coffee Shop right at the entrance: "La Vasquita"."
United States
Georg
The price is €135
includes taxes & fees
1 Nov - 2 Nov
San Francisco by Wynwood House
A modern lobby with a glass railing, a central staircase, and a view of the cityscape through large windows.

17. Las Americas Golden Tower Panama

Las Americas Golden Tower Panama
4.0 star property
Punta Paitilla, 0.9 km from Calle 50
9.0 out of 10, Wonderful, (1,145 reviews)
"Breakfast was great, friendly staff, clean rooms."
United States
Everlyn
The price is €147
includes taxes & fees
1 Nov - 2 Nov
Las Americas Golden Tower Panama
A rooftop pool with blue lounge chairs and a city skyline view.

18. Best Western Plus Panama Zen Hotel

Best Western Plus Panama Zen Hotel
4.0 star property
El Cangrejo, 1.1 km from Calle 50
9.0 out of 10, Wonderful, (1,009 reviews)
"A great hotel to stay while in Panama"
United States
Adrian
The price is €94
includes taxes & fees
2 Nov - 3 Nov
Best Western Plus Panama Zen Hotel
A rooftop pool with sun loungers and a city skyline in the background.

19. Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino
4.0 star property
El Cangrejo, 1.4 km from Calle 50
9.0 out of 10, Wonderful, (1,220 reviews)
"Breakfast, Cafe, was just perfect location"
United States
Bruno
The price is €142
includes taxes & fees
31 Oct - 1 Nov
Waymore Hotel Spa & Casino
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.

20. W Panama

W Panama
5.0 star property
Campo Alegre, 1.1 km from Calle 50
9.0 out of 10, Wonderful, (1,002 reviews)
"Had an amazing trip, the staff were amazing!!!"
United States
Naomi
The price is €247
includes taxes & fees
13 Nov - 14 Nov
W Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Compare popular hotels close to Calle 50

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A pool area with lounge chairs and umbrellas, surrounded by greenery and a multi-story building in the background.
Hyatt Regency Panama City
5.0 star property
9.6
Exceptional
495 reviews
View
A covered outdoor seating area with a view of a city skyline and water.
Plaza Paitilla Inn Hotel
3.5 star property
9.4
Exceptional
2,233 reviews
View
An outdoor patio area with tables and chairs, a pool, and a covered seating area.
Hostal Familiar Carmencita - Hostel
2.0 star property
9.4
Exceptional
13 reviews
View
A rooftop pool with clear blue water, surrounded by palm trees and a city skyline in the background.
Gran Evenia Panama
4.5 star property
9.2
Wonderful
254 reviews
View
A modern hotel entrance with a prominent 'NOVOTEL' sign, large glass windows, and geometric light patterns on the facade.
Novotel Panama City
4.0 star property
9.2
Wonderful
1,300 reviews
View

Top Calle 50 Hotel Reviews

Hyatt Regency Panama City

Hyatt Regency Panama City

10/10 Excellent
"Nice rooms! Great staff!"
Sheana 6-night trip
Posted 2 hours ago
Hyatt Regency Panama City

Other attractions near Calle 50

A cityscape with a rainbow over buildings.
Photo by Fabiola Tile
Open Photo by Fabiola Tile

Multiplaza Pacific Mall

9.0/10 (4,497 reviews)
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
See properties

Frequently asked questions

What's the area like around Calle 50?
Calle 50 is located in Panama City. This welcoming area is known for its array of dining options and major shopping area. If you're looking for a convenient place to stay, take a look at the 480 hotels and other accommodation options you'll find within a mile.
What's the best place to stay near Calle 50?
Adjacent to Calle 50, Courtyard by Marriott Panama Multiplaza Mall is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a short distance include Hotel Riu Plaza Panama and Megapolis Hotel Panamá.
How many hotels can I expect to find near Calle 50?
Expedia has 480 hotels and other accommodation options within a mile from Calle 50.
If I need to cancel the hotel reservation for my stay near Calle 50, will I receive a refund?
Yes, the majority of hotel bookings are fully refundable if cancelled before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Calle 50.
What can I see and do near Calle 50?
You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and National Bank House Museum. Iglesia del Carmen, Panama Viejo and Panama Canal Railway are notable landmarks to explore if you're in the area. You can catch a show at National Theater, Anita Villalaz Theater and Amador Theater.
How can I get to Calle 50?
Nearby metro stations include Iglesia del Carmen Station and Vía Argentina Station. If you'd like to explore farther outside of the area, you may want a car rental for your journey.