Cape Girardeau Hotel Guide - Cape Girardeau Conservation Nature Center hotels in Cape Girardeau, United States of America.

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18 Dec - 19 Dec
Tomorrow
19 Dec - 20 Dec
This weekend
19 Dec - 21 Dec
Next weekend
26 Dec - 28 Dec

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Our top choices for Cape Girardeau Conservation Nature Center hotels

Snack bar
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
0.9 km from Cape Girardeau Conservation Nature Center
9.6 out of 10, Exceptional, (102)
"It was a nice stay"
United States
Douglas
The price is €87
includes taxes & fees
1 Jan - 2 Jan 2026
Tru By Hilton Cape Girardeau
Exterior
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
2 km from Cape Girardeau Conservation Nature Center
8.8 out of 10, Excellent, (669)
"Great place "
United States
GUY
The price is €78
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau
2.5 star property
2 km from Cape Girardeau Conservation Nature Center
8.2 out of 10, Very good, (739)
"Dirty "
United States
Jon
The price is €78
includes taxes & fees
1 Jan - 2 Jan 2026
Comfort Suites Jackson-Cape Girardeau
Lobby
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
1.3 km from Cape Girardeau Conservation Nature Center
7.2 out of 10, Good, (684)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is €55
includes taxes & fees
25 Dec - 26 Dec
Quality Inn Cape Girardeau North
Lobby
Rockwood Inn

Rockwood Inn

Rockwood Inn
2.0 star property
6.2 km from Cape Girardeau Conservation Nature Center
10.0 out of 10, Exceptional, (18)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is €144
includes taxes & fees
28 Dec - 29 Dec
Rockwood Inn
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
4.5 km from Cape Girardeau Conservation Nature Center
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is €86
includes taxes & fees
23 Dec - 24 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East
2.5 star property
5.3 km from Cape Girardeau Conservation Nature Center
9.6 out of 10, Exceptional, (784)
"Excellent stay"
United States
Christina
The price is €98
includes taxes & fees
27 Dec - 28 Dec
Hampton Inn Cape Girardeau I 55 East
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
7.4 km from Cape Girardeau Conservation Nature Center
9.6 out of 10, Exceptional, (468)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is €112
includes taxes & fees
28 Dec - 29 Dec
Courtyard by Marriott Cape Girardeau Downtown
Free daily buffet breakfast
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
4.9 km from Cape Girardeau Conservation Nature Center
9.4 out of 10, Exceptional, (1003)
"Very friendly staff and great breakfast"
United States
Ray
The price is €86
includes taxes & fees
23 Dec - 24 Dec
Drury Inn & Suites Cape Girardeau
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
5.1 km from Cape Girardeau Conservation Nature Center
9.4 out of 10, Exceptional, (1000)
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
United States
Brian
The price is €91
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
10.3 km from Cape Girardeau Conservation Nature Center
9.6 out of 10, Exceptional, (1004)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is €75
includes taxes & fees
21 Dec - 22 Dec
Drury Inn & Suites Jackson MO
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
6.3 km from Cape Girardeau Conservation Nature Center
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is €85
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
7.4 km from Cape Girardeau Conservation Nature Center
9.4 out of 10, Exceptional, (474)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is €93
includes taxes & fees
22 Dec - 23 Dec
The Riverview
Free daily buffet breakfast
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
4.9 km from Cape Girardeau Conservation Nature Center
9.0 out of 10, Wonderful, (1000)
"Great stay"
United States
Heather
The price is €67
includes taxes & fees
23 Dec - 24 Dec
Pear Tree Inn Cape Girardeau West
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG
2.5 star property
6.5 km from Cape Girardeau Conservation Nature Center
8.2 out of 10, Very good, (882)
"Room was clean and spacious."
United States
George
The price is €79
includes taxes & fees
19 Jan - 20 Jan 2026
Candlewood Suites Cape Girardeau by IHG
Economy Single Room, 1 Queen Bed, Kitchenette
Town House Inn

Town House Inn

Town House Inn
2.5 star property
7.2 km from Cape Girardeau Conservation Nature Center
7.6 out of 10, Good, (423)
"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
The price is €65
includes taxes & fees
21 Dec - 22 Dec
Town House Inn
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

Town House Inn Cape Giradreau
2.5 star property
4.8 km from Cape Girardeau Conservation Nature Center
6.0 out of 10, (206)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is €55
includes taxes & fees
15 Jan - 16 Jan 2026
Town House Inn Cape Giradreau
Front of property
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
5 km from Cape Girardeau Conservation Nature Center
9.0 out of 10, Wonderful, (1002)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is €67
includes taxes & fees
23 Dec - 24 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Conservation Nature Center Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Didn’t eat the breakfast but I’m sure it is wonderful. Everything from the Check in process to the condition of the rooms to the comfort of the stay was worth the money "
Corrie 1-night trip
Posted 1 day ago
Drury Plaza Hotel Cape Girardeau Conference Center

Hotels near other Cape Girardeau Conservation Nature Center attractions

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Cape Splash Family Aquatic Center

Bring the children to Cape Splash Family Aquatic Center and have a fun-filled day at this theme park in Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Cape Girardeau Conservation Nature Center?
Cape Girardeau Conservation Nature Center is located in Cape Girardeau, a historic area that travellers like for its riverfront. You'll find 60 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near Cape Girardeau Conservation Nature Center?
Tru By Hilton Cape Girardeau is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.5 mi (0.9 km) from Cape Girardeau Conservation Nature Center. Another good choice is Quality Inn Cape Girardeau North, located just 0.8 mi (1.3 km) away.
How many hotels will I find close to Cape Girardeau Conservation Nature Center?
Expedia has 60 hotels and other accommodation options a few miles from Cape Girardeau Conservation Nature Center.
If I need to cancel the hotel reservation for my stay near Cape Girardeau Conservation Nature Center, will I receive a refund?
Yes, you'll find most hotel room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the top deals on offer near Cape Girardeau Conservation Nature Center.
What can I see and do near Cape Girardeau Conservation Nature Center?
Create some family memories at Cape Splash Family Aquatic Center and Lazy L Safari Park. You might plan a visit to Show Me Center or eDen Spa & Salon while you're in the area. Southeast Missouri State University and Isle Casino Cape Girardeau are some sights worth a visit in the area.