Antigua Guatemala Hotel Guide - Casa Santo Domingo Museum hotels in Antigua Guatemala, Guatemala.

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Casa Santo Domingo Museum hotels

Casa Santa Rosa Hotel Boutique

Casa Santa Rosa Hotel Boutique
3.5 star property
Historic Center, 0.3 km from Casa Santo Domingo Museum
9.6 out of 10, Exceptional, (332 reviews)
"Best place to stay in Antigua!!"
United States
Maria
The price is €145
includes taxes & fees
25 Jan - 26 Jan
Casa Santa Rosa Hotel Boutique

Hotel Posada de Don Rodrigo Antigua

Hotel Posada de Don Rodrigo Antigua
3.5 star property
Historic Center, 0.7 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (674 reviews)
"Friendly staff, clean rooms the location was excellent. "
United States
Elias
The price is €202
includes taxes & fees
16 Feb - 17 Feb
Hotel Posada de Don Rodrigo Antigua

All Suite El Marques de Antigua

All Suite El Marques de Antigua
3.5 star property
1 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (320 reviews)
"Very clean, excellent location and super friendly staff"
United States
Aliasger
All Suite El Marques de Antigua

Los Pasos Boutique Hotel & Spa

Los Pasos Boutique Hotel & Spa
4.5 star property
0.7 km from Casa Santo Domingo Museum
9.4 out of 10, Exceptional, (1,002 reviews)
"Great stay "
United States
BETTE
The price is €163
includes taxes & fees
29 Jan - 30 Jan
Los Pasos Boutique Hotel & Spa

Hostal Antigueño - Hostel

Hostal Antigueño - Hostel
2.0 star property
0.3 km from Casa Santo Domingo Museum
9.0 out of 10, Wonderful, (35 reviews)
"Great place, great people! Highly recommend!"
Canada
Cody
The price is €36
includes taxes & fees
25 Jan - 26 Jan
Hostal Antigueño - Hostel

Hotel Casa Anturio

Hotel Casa Anturio
3.0 star property
Historic Center, 0.9 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (59 reviews)
"The staff are fantastic and amazing "
Australia
Rhys
The price is €57
includes taxes & fees
28 Jan - 29 Jan
Hotel Casa Anturio

Hotel Eterna Primavera Antigua

Hotel Eterna Primavera Antigua
3.0 star property
Historic Center, 0.3 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (271 reviews)
"The room was cozy and clean. The bed was comfortable. My only complaint would be that the WiFi in the room was very bad, I had to go to the dining area to be able to use my computer. "
United States
Nancy
The price is €88
includes taxes & fees
8 Feb - 9 Feb
Hotel Eterna Primavera Antigua

Casa Quetzalli Los Nazarenos

Casa Quetzalli Los Nazarenos
2.0 star property
1.3 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (34 reviews)
"The hotel was too good to rest, we stayed 5 nights and it was really clean and confortable, I really recommend this place, plus the price is great! "
Mexico
Samuel
The price is €40
includes taxes & fees
9 Feb - 10 Feb
Casa Quetzalli Los Nazarenos

Sonnenhaus

Sonnenhaus
2.0 star property
Barrio de La Concepción, < 0.1 km from Casa Santo Domingo Museum
8.6 out of 10, Excellent, (14 reviews)
"Very quiet and calm accommodation. Very clean and in a great location. Would def stay again"
Germany
Viktoria
The price is €25
includes taxes & fees
26 Jan - 27 Jan
Sonnenhaus

Las Camelias Inn

Las Camelias Inn
3.0 star property
Historic Center, 0.3 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (591 reviews)
"Super friendly staff, beautiful place!"
United States
Fabiola
The price is €84
includes taxes & fees
29 Jan - 30 Jan
Las Camelias Inn

Casa Buho B&B

Casa Buho B&B
3.0 star property
Santa Ana, 1.5 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (49 reviews)
"Great place !!"
United States
Abner Israel Polanco
The price is €58
includes taxes & fees
3 Feb - 4 Feb
Casa Buho B&B

Hotel Casa Carmina

Hotel Casa Carmina
4.0 star property
1.1 km from Casa Santo Domingo Museum
9.0 out of 10, Wonderful, (222 reviews)
"The room was a great deal and the staff was extremely helpful and polite. "
United States
Sherri Y.
Hotel Casa Carmina

Meson Panza Verde

Meson Panza Verde
3.5 star property
1 km from Casa Santo Domingo Museum
9.2 out of 10, Wonderful, (442 reviews)
"Great location "
United States
Jami
The price is €176
includes taxes & fees
2 Feb - 3 Feb
Meson Panza Verde

Naif Boutique Hotel

Naif Boutique Hotel
3.0 star property
Historic Center, 1 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (388 reviews)
"Friendly staff. Great breakfast "
United States
jeffrey
The price is €119
includes taxes & fees
26 Jan - 27 Jan
Naif Boutique Hotel

Hotel La Posadita Antigua

Hotel La Posadita Antigua
3.0 star property
1 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (45 reviews)
"Nice place to stay and good location "
United States
Alfredo
Hotel La Posadita Antigua

La Capitanía

La Capitanía
3.0 star property
1.2 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (63 reviews)
"Clean room, excellent staff"
United States
Georgina
The price is €73
includes taxes & fees
25 Jan - 26 Jan
La Capitanía

Cermeños House

Cermeños House
2.0 star property
Historic Center, 1 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (36 reviews)
"Elizabeth and the staff will treat you like family-a wonderful place!"
United States
LESLIE
The price is €53
includes taxes & fees
5 Feb - 6 Feb
Cermeños House

Why Not Hotel

Why Not Hotel
3.0 star property
Historic Center, 0.8 km from Casa Santo Domingo Museum
8.4 out of 10, Very good, (153 reviews)
"clean and spacious room "
Italy
Teresa
The price is €56
includes taxes & fees
1 Feb - 2 Feb
Why Not Hotel

El Calvario Lofts

El Calvario Lofts
3.0 star property
1.3 km from Casa Santo Domingo Museum
8.8 out of 10, Excellent, (18 reviews)
"Great stay, and very comfortable. A bit cold but the staff provided extra blankets. Laundry service for an additional fee. "
United States
Jonathan
The price is €97
includes taxes & fees
28 Jan - 29 Jan
El Calvario Lofts

Socialtel Antigua

Socialtel Antigua
3.0 star property
0.9 km from Casa Santo Domingo Museum
8.6 out of 10, Excellent, (112 reviews)
"The room was more than expected full of Guatemalan culture. It was nice and clean and friendly staff. "
United States
German
The price is €87
includes taxes & fees
2 Feb - 3 Feb
Socialtel Antigua
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Casa Santo Domingo Museum Hotel Reviews

Hotels near other Casa Santo Domingo Museum attractions

Frequently asked questions

What's the area like around Casa Santo Domingo Museum?
Casa Santo Domingo Museum is located in a historic area of Antigua Guatemala known for its major shopping area. If you're looking for a convenient place to stay, take a look at the 476 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to Casa Santo Domingo Museum?
Adjacent to Casa Santo Domingo Museum, Hotel Museo Spa Casa Santo Domingo is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and 2 restaurants. Other good choices close by include Porta Hotel Antigua and El Convento Boutique Hotel.
How many hotels are there near Casa Santo Domingo Museum?
Expedia has 476 hotels and other accommodation options within a mile from Casa Santo Domingo Museum.
If I need to cancel the hotel reservation for my stay near Casa Santo Domingo Museum, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might still have the option to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to review the best deals available near Casa Santo Domingo Museum.
What can I see and do near Casa Santo Domingo Museum?
You might want to spend some time browsing the exhibits at Antigua Guatemala Colonial Art Museum, La Azotea Cultural Center or Jade Maya Factory and Museum. Explore notable local landmarks like Las Capuchinas Convent, Santa Clara Convent and Santa Catalina Arch. Spend some time exploring the the natural beauty of Central Park, Tanque La Unión and El Reposo Spa.