Uptown

Collinsville

A tall water tower with a red and white striped top, surrounded by trees and a clear blue sky.
A tall, cylindrical structure with a red and white striped pattern and a label reading "Brock's Old Original Catsup."

Stay near popular Uptown attractions

Things to do


Top hotels in Uptown

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

3 out of 5
2 South 4th Street St. Louis MO
The price is €142 per night from 14 Dec to 15 Dec
€142
14 Dec - 15 Dec
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and 2 hot tubs. Our guests praise the breakfast and the pool in their reviews. ...
Drury Plaza Hotel St. Louis at the Arch
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

3.5 out of 5
7750 Carondelet Avenue St. Louis MO
The price is €106 per night from 22 Nov to 23 Nov
€106
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and a 24-hour fitness centre. Our guests praise the breakfast and the pool ...
8.8/10 Excellent! (3,520 reviews)
"Strange place and yet an absolute gem for the money. Very clean, slightly strangely unpopulated, nice quality furniture and amenities, good breakfast. Just vaguely off but for the value - I'd stay a hundred nights out of a hundred."

Reviewed on 12 Nov 2026

Clayton Plaza Hotel & Extended Stay
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

4 out of 5
315 Chestnut St St. Louis MO
The price is €114 per night from 26 Nov to 27 Nov
€114
26 Nov - 27 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, 3 restaurants and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms ...
8.6/10 Excellent! (4,381 reviews)
"The room as well as the bathroom could use an update. There was a smelly unpleasant odor in the room. The water was very slow to warm up for shower time. Breakfast was amazing on site."

Reviewed on 13 Nov 2026

Hyatt Regency St. Louis at The Arch
Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station

3 out of 5
2211 Market Street St. Louis MO
The price is €110 per night from 22 Nov to 23 Nov
€110
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the restaurant in their ...
Pear Tree Inn St. Louis Near Union Station
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4 out of 5
3550 Samuel Sheppard Drive St. Louis MO
The price is €110 per night from 22 Nov to 23 Nov
€110
22 Nov - 23 Nov
includes taxes & fees
Stay at this business-friendly hotel in St. Louis. Enjoy free Wi-Fi, a rooftop terrace and breakfast (surcharge). Our guests praise the helpful staff and the ...
8.8/10 Excellent! (1,168 reviews)
"Interesting art installment and convenient location, hotel and restaurant staff were all very friendly."

Reviewed on 13 Nov 2026

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
21C Museum Hotel St Louis

21C Museum Hotel St Louis

4.5 out of 5
1528 Locust street St. Louis MO
The price is €157 per night from 6 Dec to 7 Dec
€157
6 Dec - 7 Dec
includes taxes & fees
Stay at this luxury hotel in St. Louis. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the pool and the restaurant in their reviews. ...
9/10 Wonderful! (2,153 reviews)
"I booked this hotel to go to a concert at the Stifel Theatre. The hotel has interesting decor and ambiance. The staff and experience were a huge disappointment. I spoke with an older gentleman on the phone weeks in advance about parking, and he checked me in on the day. He was excellent. 1. Our room ..."

Reviewed on 12 Nov 2026

21C Museum Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

Eastport

While visiting Eastport, you might make a stop by sights like Splash City Family Waterpark and Gateway Conference Center.

Mulberry Hills

Though Mulberry Hills may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.

Historic Downtown Collinsville

Though Historic Downtown Collinsville may not have many top sights, you can venture to the surrounding area to see attractions like World's Largest Catsup Bottle and Kruta Bakery.



Uptown

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