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Check prices for these dates

In two weeks
27 Mar - 29 Mar
In two months
8 May - 10 May
In three months
5 Jun - 7 Jun
In four months
3 Jul - 5 Jul

Our top choices for Defiance apartments

Living area

Apartment in Saint Charles

The Cul-de-Sac Retreat
8.4 out of 10, Very good, (9 reviews)
"Great house, great location - close to the St. Charles convention center"
United States
Joe H.
The Cul-de-Sac Retreat
Exterior

Apartment in Maryland Heights

Sunny SparkingClean King bed Apt- CreveCoeurPark
9.8 out of 10, Exceptional, (12 reviews)
"Good Stay"
United States
Lanai
The price is €263
includes taxes & fees
15 Mar - 16 Mar
Sunny SparkingClean King bed Apt- CreveCoeurPark
Interior

Apartment in St. Charles Historic District

Amazing Renovated Historic Loft on Main Street
10.0 out of 10, Exceptional, (59 reviews)
"Great place and location. Owners were easy to work with."
United States
Cory M.
The price is €239
includes taxes & fees
16 Mar - 17 Mar
Amazing Renovated Historic Loft on Main Street
Exterior

Apartment in St. Charles Historic District

Stay on Main Historic Studio
9.0 out of 10, Wonderful, (33 reviews)
"Nice property.. Clean. "
United States
Belinda J.
The price is €173
includes taxes & fees
18 Mar - 19 Mar
Stay on Main Historic Studio
TV

Apartment in St. Charles Historic District

Main Street Balcony Apartment
9.6 out of 10, Exceptional, (36 reviews)
"Great location for shopping and a lot of restaurants nearby. Beds were very comfortable. "
United States
Brooke I.
Main Street Balcony Apartment
TV

Apartment in St. Charles Historic District

1st Capitol Mansion - Suite 401
7.6 out of 10, Good, (8 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
The price is €357
includes taxes & fees
13 Apr - 14 Apr
1st Capitol Mansion - Suite 401
Interior

Apartment in St. Charles Historic District

The Lofts of North Main Street
9.6 out of 10, Exceptional, (165 reviews)
"Host was very responsive and location was perfect"
United States
Peggy K.
The price is €225
includes taxes & fees
16 Mar - 17 Mar
The Lofts of North Main Street
Interior

Apartment in St. Charles Historic District

The Historic Bricks on Main
9.0 out of 10, Wonderful, (17 reviews)
"Nice location, street parking can be tricky. Apartment was clean. "
United States
Maggie H.
The price is €197
includes taxes & fees
18 Mar - 19 Mar
The Historic Bricks on Main
Fridge, microwave, oven, stovetop

Apartment in St. Charles Historic District

Historic Main St. Customs House Upstairs Apartment
9.6 out of 10, Exceptional, (36 reviews)
"Great Stay and great location! "
United States
Angela
The price is €306
includes taxes & fees
22 Mar - 23 Mar
Historic Main St. Customs House Upstairs Apartment
Dining

Apartment in Maryland Heights

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
9.6 out of 10, Exceptional, (4 reviews)
"It was an easy experience renting this place"
United States
Dominic M.
The price is €197
includes taxes & fees
5 Apr - 6 Apr
Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
Interior

Apartment in Saint Charles

2 Bdr Upstairs Apt Walking Distance to Main St
9.4 out of 10, Exceptional, (3 reviews)
"The overall vibe struck me as a college town apartment: the building was fine, but finishes were underwhelming. The unit itself was a little small, but workable. We had a scenario where the heater seemed to be acting up; the room actually got warmer after we shut the heat off. It was a pleasant enough stay, and served the purpose we had come for: visiting our adult children. It was a bit of a walk to get to the historic district."
United States
Greg L.
The price is €296
includes taxes & fees
20 Mar - 21 Mar
2 Bdr Upstairs Apt Walking Distance to Main St
Smart TV

Apartment in St. Charles Historic District

Prime Loft of Main Street
9.8 out of 10, Exceptional, (105 reviews)
"Our host answered all my questions quickly and correctly. We found the property to be perfect for our visit. It was clean and well kept."
United States
Anonymous traveller
The price is €239
includes taxes & fees
18 Mar - 19 Mar
Prime Loft of Main Street
Fridge, microwave, stovetop, toaster

Apartment in St. Charles Historic District

Charming Duplex on Main
9.8 out of 10, Exceptional, (17 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
Charming Duplex on Main
1 bedroom, WiFi, bed sheets

Apartment in St. Charles Historic District

Duplex Hideaway in St. Charles, MO
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
Duplex Hideaway in St. Charles, MO
TV

Apartment in St. Charles Historic District

6th street 101 - Walk to Main St
10.0 out of 10, Exceptional, (1 review)
The price is €246
includes taxes & fees
15 Mar - 16 Mar
6th street 101 - Walk to Main St
TV

Apartment in New Haven

Back Door Guest Suite, Zia My Retreat
10.0 out of 10, Exceptional, (6 reviews)
"Very comfortable, spacious, great location for canoe trip. "
United States
Carolyn B.
Back Door Guest Suite, Zia My Retreat
Interior

Apartment in Maryland Heights

AK`s STL Pearl Grey House - Game Room
9.0 out of 10, Wonderful, (8 reviews)
"Great stay! We had everything we needed and the communication was perfect!"
United States
Melodie B.
AK`s STL Pearl Grey House - Game Room
Fridge, microwave, oven, stovetop

Apartment in Moscow Mills

Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
10.0 out of 10, Exceptional, (12 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
Quiet 2BR Retreat on 7 Acres | Sleeps 6, Fast WiFi
Exterior detail

Apartment in Washington

2nd Street Loft - Riverview
10.0 out of 10, Exceptional, (1 review)
"My wife and I absolutely loved this place and will definitely stay there again. The amenities were thought out very well, bed was comfortable, the kitchen area very well thought out and everything in the kitchen was handy. The bathroom was large for a loft and the entire place was very very clean. The host answered my questions in a timely manner. Cannot think of anything we would change"
United States
Mike M.
The price is €149
includes taxes & fees
15 Mar - 16 Mar
2nd Street Loft - Riverview
TV

Apartment in St. Charles Historic District

Walk to Main St | Pet-Friendly Apt
8.8 out of 10, Excellent, (13 reviews)
"Great space! Very comfortable! "
United States
Mary H.
The price is €253
includes taxes & fees
23 Mar - 24 Mar
Walk to Main St | Pet-Friendly Apt
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

6/10 Okay
"If you stay here be prepared for a boat load of hidden fees. After paying in full, you will be required to pay a 100 dollar deposit when you arrive. They will also charge over 20 dollars in "resort fees" billed as your preparing to check out. Great experience but the price quoted here is NOT what you will pay. Feels very sheisty and backhanded."
Jeremy 1-night trip
Posted 2 hours ago
Ameristar Casino Resort and Spa

Find out more about Defiance

Defiance Apartments information

Number of reviews
405
Accommodation
103 Apartments
Lowest Price
€149
Highest Price
€357

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: Prime Loft of Main Street: Located in St. Charles , 19.2 mi/30.9 km from the heart of Defiance. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . The Lofts of North Main Street: Located 19.2 mi/30.8 km away in St. Charles . Free WiFi, a sofa bed and a Smart TV are included . Access to on-site laundry facilities is available on site . Western-Themed 2-Bedroom Hideout for Outlaws 204-2: Located in St. Charles , 19.1 mi/30.7 km away. Includes a balcony and a Smart TV . Access to on-site laundry facilities is available on site . Historic Main Street Heritage Retreat: Located 18.5 mi/29.7 km away in St. Charles . A patio, a sofa bed and a Smart TV are included . Access to on-site laundry facilities is available on site . The Wild West Getaway- 204-1: Located in St. Charles , 19.1 mi/30.7 km from Defiance. Includes a patio and a Smart TV . Access to on-site laundry facilities is available on site .
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Chandler Hill Vineyards and Sugar Creek Winery are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.