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Check prices for these dates

In two weeks
13 Feb - 15 Feb
In two months
27 Mar - 29 Mar
In three months
24 Apr - 26 Apr
In four months
22 May - 24 May

Our top choices for Defiance apartments

TV, fireplace

2-bedroom apartment in awesome West County with AC, Fitness Room and Laundry

2-bedroom apartment in awesome West County with AC, Fitness Room and Laundry
St. Louis
10.0 out of 10, Exceptional, (1 review)
The price is €110
includes taxes & fees
28 Jan - 29 Jan
2-bedroom apartment in awesome West County with AC, Fitness Room and Laundry
Fridge, microwave, oven, stovetop

The Hidden Gem - 2BR Basement Apartment on 7 Acres

The Hidden Gem - 2BR Basement Apartment on 7 Acres
Moscow Mills
10.0 out of 10, Exceptional, (12 reviews)
"Great place, nice neighborhood. "
United States
Julie L.
The price is €236
includes taxes & fees
26 Feb - 27 Feb
The Hidden Gem - 2BR Basement Apartment on 7 Acres
Exterior

2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (2 reviews)
"Easy check in/check out, super nice host! Very clean space. "
United States
Emily L.
The price is €144
includes taxes & fees
9 Feb - 10 Feb
2nd Street -Deck Suite (back entrance)
TV

6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (1 review)
The price is €217
includes taxes & fees
28 Jan - 29 Jan
6th street 101 - Walk to Main St
Living area

The Cul-de-Sac Retreat

The Cul-de-Sac Retreat
Saint Charles
8.4 out of 10, Very good, (9 reviews)
"Great house, great location - close to the St. Charles convention center"
United States
Joe H.
The price is €270
includes taxes & fees
9 Feb - 10 Feb
The Cul-de-Sac Retreat
1 bedroom, WiFi, bed sheets

Duplex Hideaway in St. Charles, MO

Duplex Hideaway in St. Charles, MO
St. Charles Historic District
10.0 out of 10, Exceptional, (5 reviews)
"I will stay here again. It was a great location for my visit. Lots of room and amenities. Highly recommend this location if you are visiting the St Louis area. Barely a mile to get to Hwy 70, so easy access to St Louis, St Peter's, Wentzville etc. Maybe two blocks from Historic St Charles and Ameristar Casino."
United States
Karen M.
The price is €192
includes taxes & fees
28 Jan - 29 Jan
Duplex Hideaway in St. Charles, MO
Fridge, microwave, oven, stovetop

Main Street Living! 2 Bedroom Unit right On Main!

Main Street Living! 2 Bedroom Unit right On Main!
St. Charles Historic District
9.6 out of 10, Exceptional, (34 reviews)
"Great Stay and great location! "
United States
Angela
The price is €298
includes taxes & fees
28 Jan - 29 Jan
Main Street Living! 2 Bedroom Unit right On Main!
Exterior

Sunny SparkingClean King bed Apt- CreveCoeurPark

Sunny SparkingClean King bed Apt- CreveCoeurPark
Maryland Heights
9.8 out of 10, Exceptional, (12 reviews)
"Good Stay"
United States
Lanai
Sunny SparkingClean King bed Apt- CreveCoeurPark
Interior

Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (58 reviews)
"Great place and location. Owners were easy to work with."
United States
Cory M.
The price is €212
includes taxes & fees
28 Jan - 29 Jan
Amazing Renovated Historic Loft on Main Street
Dining

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!

Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
Maryland Heights
9.6 out of 10, Exceptional, (4 reviews)
"It was an easy experience renting this place"
United States
Dominic M.
The price is €169
includes taxes & fees
8 Feb - 9 Feb
Great for Business Travelers! Studio Suite Near Edward Jones! Shared Pool + Free Breakfast!
Interior

Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street

Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street
Saint Charles
9.0 out of 10, Wonderful, (2 reviews)
"The overall vibe struck me as a college town apartment: the building was fine, but finishes were underwhelming. The unit itself was a little small, but workable. We had a scenario where the heater seemed to be acting up; the room actually got warmer after we shut the heat off. It was a pleasant enough stay, and served the purpose we had come for: visiting our adult children. It was a bit of a walk to get to the historic district."
United States
Greg L.
The price is €218
includes taxes & fees
8 Feb - 9 Feb
Luxurious 2-Bedroom Abode with Elevated Comforts Near Main Street
Exterior

Studio on Historic Main by StayLage

Studio on Historic Main by StayLage
St. Charles Historic District
9.0 out of 10, Wonderful, (33 reviews)
"Nice property.. Clean. "
United States
Belinda J.
The price is €163
includes taxes & fees
28 Jan - 29 Jan
Studio on Historic Main by StayLage
Smart TV

Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (104 reviews)
"The loft was very nice, very clean, well appointed, and in a perfect location. I highly recommend this property!"
United States
Mary ann S.
The price is €205
includes taxes & fees
1 Feb - 2 Feb
Prime Loft of Main Street
Interior

The Historic Bricks on Main

The Historic Bricks on Main
St. Charles Historic District
8.8 out of 10, Excellent, (15 reviews)
"Had a wonderful stay. Host was very responsive. Great stay in the middle of everything- so we could walk out and shop or grab a bite to eat. "
United States
Alison C.
The price is €172
includes taxes & fees
28 Jan - 29 Jan
The Historic Bricks on Main
Interior

The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (159 reviews)
"Very nice place near all the action. "
United States
Weston G.
The price is €205
includes taxes & fees
28 Jan - 29 Jan
The Lofts of North Main Street
Fridge, microwave, stovetop, toaster

Charming Duplex on Main

Charming Duplex on Main
St. Charles Historic District
10.0 out of 10, Exceptional, (16 reviews)
"We had an AMAZING time here and you can't beat the close walking distance to main st!! Absolutely loved our stay. "
United States
Wendy K.
The price is €200
includes taxes & fees
1 Feb - 2 Feb
Charming Duplex on Main
TV

Back Door Guest Suite, Zia My Retreat

Back Door Guest Suite, Zia My Retreat
New Haven
10.0 out of 10, Exceptional, (6 reviews)
"Very comfortable, spacious, great location for canoe trip. "
United States
Carolyn B.
The price is €196
includes taxes & fees
26 Feb - 27 Feb
Back Door Guest Suite, Zia My Retreat
A heated pool

Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
The price is €136
includes taxes & fees
1 Feb - 2 Feb
Great for Business Travelers! Pool + Gym
Interior

AK`s STL Pearl Grey House - Game Room

AK`s STL Pearl Grey House - Game Room
Maryland Heights
9.0 out of 10, Wonderful, (8 reviews)
"My kids loved this house! It was very comfortable for my family of 7. We were able to cook dinner, play games, watch TV, and were within close proximity to all things St. Louis. We would definitely stay here again. "
United States
Tiffanny B.
The price is €401
includes taxes & fees
8 Feb - 9 Feb
AK`s STL Pearl Grey House - Game Room
Smart TV

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.6 out of 10, Excellent, (4 reviews)
"Great option for group of 5-6 riding Katy Trail "
United States
Gary G.
The price is €341
includes taxes & fees
28 Jan - 29 Jan
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Drury Plaza Hotel St. Louis Chesterfield

Drury Plaza Hotel St. Louis Chesterfield

10/10 Excellent
"After many years of travelling hotel chains for kids hockey, this was my first time at a Drury hotel. By far the best travel hotel we have stayed at; rooms are large and clean, staff exceptional polite, excellent hot breakfast. What I was really amazed with was their daily happy hour; food is like a meal with many options plus 3 drink tickets per person per day; great value for sure 👍; very impressed "
Donald 3-night trip
Posted 1 day ago
Drury Plaza Hotel St. Louis Chesterfield

Find out more about Defiance

Defiance Apartments information

Number of reviews
457
Accommodation
103 Apartments
Lowest Price
€110
Highest Price
€401

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Below you'll find a top apartment in the area: 'the Ruebling House': Bright, Modern, & Renovated!: Situated in Defiance , 0.1 mi/0.2 km from the heart of Defiance.
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
Matson Hill Park Trailhead and August A. Busch Memorial Conservation Area are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.