A rustic covered bridge with a wooden structure and red accents, surrounded by lush greenery and trees.

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Check prices for these dates

In two weeks
9 Oct - 11 Oct
In two months
20 Nov - 22 Nov
In three months
18 Dec - 20 Dec
In four months
15 Jan - 17 Jan

Our top choices for Defiance apartments

A hotel pool area with a rectangular pool, lounge chairs, and a wooden bench.

1. Great for Business Travelers! Pool + Gym

Great for Business Travelers! Pool + Gym
O'Fallon
Great for Business Travelers! Pool + Gym
A room with a dark wooden wall, a brown leather sofa, a white door, and a patterned wall.

2. Stylish1BRStudioCleanQuietandCozy

Stylish1BRStudioCleanQuietandCozy
Saint Charles
10.0 out of 10, Exceptional, (3 reviews)
"Room was very clean with little to no issues at all. Host was super easy to work with and get information from. This spot is within 15-20minutes OR LESS to anything you’d need to do in the ofallon and surrounding areas. I’d book it again if I needed to."
United States
Mike S.
The price is €225
includes taxes & fees
28 Sept - 29 Sept
Stylish1BRStudioCleanQuietandCozy
A two-story building with a balcony, a staircase, and a gated entrance.

3. 2nd Street -Deck Suite (back entrance)

2nd Street -Deck Suite (back entrance)
Washington
10.0 out of 10, Exceptional, (9 reviews)
"Great comfortable mini apartment style."
United States
Ozzy
The price is €168
includes taxes & fees
28 Sept - 29 Sept
2nd Street -Deck Suite (back entrance)
A bedroom with a bed, a dresser, a mirror, a ceiling fan, and a door leading to another room.

4. Enjoyable 2-bedroom apartment at St. Peters; Near STL

Enjoyable 2-bedroom apartment at St. Peters; Near STL
St. Peters
The price is €259
includes taxes & fees
28 Oct - 29 Oct
Enjoyable 2-bedroom apartment at St. Peters; Near STL
A set of stone steps leading to a garage with a car parked inside.

5. Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues

Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
Ballwin
7.8 out of 10, Good, (24 reviews)
"Rooms were clean and everything we needed for our stay."
United States
Keith K.
The price is €133
includes taxes & fees
4 Oct - 5 Oct
Studio, sleeps 5, short drive to Hidden Valley Ski Resort, parks &concert venues
A front door with a sign for '2nd St Loft' and a 'Self Check In' option.

6. 2nd Street Loft - Riverview

2nd Street Loft - Riverview
Washington
10.0 out of 10, Exceptional, (17 reviews)
"Beautiful loft! Great location, walking distance to several restaurants on the river . "
United States
Christy D.
The price is €157
includes taxes & fees
29 Sept - 30 Sept
2nd Street Loft - Riverview
A laundry room with a washer and dryer, a white laundry basket, and a door with a keyhole.

7. Otto's Third | River View Loft by Borgia Church

Otto's Third | River View Loft by Borgia Church
Washington
The price is €459
includes taxes & fees
11 Oct - 12 Oct
Otto's Third | River View Loft by Borgia Church

8. Family Friendly w/ Game Room in Quiet Neighborhood

Family Friendly w/ Game Room in Quiet Neighborhood
Wentzville
10.0 out of 10, Exceptional, (2 reviews)
"Nice house for our week in Lake St. Louis area. Accurate description of what you are getting and clean house. Would stay again if we are back in the area"
United States
Campbell W.
The price is €417
includes taxes & fees
28 Sept - 29 Sept
Family Friendly w/ Game Room in Quiet Neighborhood
A hotel lobby with a staircase, a reception desk, and a chandelier.

9. 2 Queen Beds | Non-Smoking, Kitchen

2 Queen Beds | Non-Smoking, Kitchen
Westport
9.2 out of 10, Wonderful, (43 reviews)
"Fantastic place!"
United States
Anonymous traveller
The price is €59
includes taxes & fees
6 Oct - 7 Oct
2 Queen Beds | Non-Smoking, Kitchen
A living room with a white sofa, two armchairs, a wooden coffee table, and a side table with a plant.

10. The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail

The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
Marthasville
8.4 out of 10, Very good, (5 reviews)
"This was the perfect place for my friends and I to stay in Marthasville. Lots of space and amenities. We did not use the complimentary breakfast, but is a great addition. Would recommend to anyone staying in the area. "
United States
Adam K.
The price is €378
includes taxes & fees
28 Sept - 29 Sept
The FarmHouse 3bd/2ba B&B in MO Wine Country & Katy Trail
A staircase with white railings and a ceiling fan.

11. Amazing Renovated Historic Loft on Main Street

Amazing Renovated Historic Loft on Main Street
St. Charles Historic District
10.0 out of 10, Exceptional, (68 reviews)
"Lovely accommodations, very clean, well equipped, great location. "
United States
Emily B.
The price is €218
includes taxes & fees
28 Sept - 29 Sept
Amazing Renovated Historic Loft on Main Street
A hallway with a door, two potted plants, a doormat, and a view of a brick building through large windows.

12. Dog-Friendly 2BR | Walk to Main Street

Dog-Friendly 2BR | Walk to Main Street
Saint Charles
8.0 out of 10, Very good, (5 reviews)
"The best price-value ratio. Quiet neighborhood, close to the city center."
United States
Tamas P.
The price is €280
includes taxes & fees
11 Oct - 12 Oct
Dog-Friendly 2BR | Walk to Main Street
A living room with a black leather sofa, two grey armchairs, a wooden coffee table, and a wall clock.

13. 6th street 101 - Walk to Main St

6th street 101 - Walk to Main St
St. Charles Historic District
10.0 out of 10, Exceptional, (3 reviews)
"Excellent"
United States
Scott N.
6th street 101 - Walk to Main St
A cozy living room with a sofa, chairs, a coffee table, and a clock.

14. 1st Capitol Mansion - Suite 401

1st Capitol Mansion - Suite 401
St. Charles Historic District
7.4 out of 10, Good, (9 reviews)
"Nice property and a great location to all the shops and restaurants that St. Charles has to offer. The place was clean and nicely updated. Will definitely stay here again!"
United States
Emily L.
1st Capitol Mansion - Suite 401
A neatly made bed with a stack of folded towels, a bedside lamp, and a ceiling fan in a room with a large window and a wall-mounted artwork.

15. Walk to Main | Pet-Friendly Yard & Workspace

Walk to Main | Pet-Friendly Yard & Workspace
St. Charles Historic District
10.0 out of 10, Exceptional, (12 reviews)
"Very close to downtown St. Charles and the Kati Trail. The home is cute and bed is comfortable. Easy check in process and fenced in back yard was nice to have."
United States
Jessica S.
The price is €271
includes taxes & fees
12 Oct - 13 Oct
Walk to Main | Pet-Friendly Yard & Workspace
A spacious living area with a wooden floor, a dining table with chairs, a flat-screen TV mounted on the wall, and a kitchen area with modern appliances.

16. The Lofts of North Main Street

The Lofts of North Main Street
St. Charles Historic District
9.6 out of 10, Exceptional, (193 reviews)
"Very comfortable bed. Well stocked kitchen. Nice covered porch. Great neighborhood."
United States
Carla K.
The price is €218
includes taxes & fees
28 Sept - 29 Sept
The Lofts of North Main Street
A modern kitchen with white cabinets, a built-in microwave, a stove, and a window providing natural light.

17. Pet-Friendly Duplex | Historic Main

Pet-Friendly Duplex | Historic Main
St. Charles Historic District
10.0 out of 10, Exceptional, (25 reviews)
"Great location"
United States
todd p.
Pet-Friendly Duplex | Historic Main
A cozy living room with a brick wall, a white sofa with colorful cushions, a small black table, and a potted plant.

18. Prime Loft of Main Street

Prime Loft of Main Street
St. Charles Historic District
9.8 out of 10, Exceptional, (120 reviews)
"Host was great. The cutest place in the perfect spot! "
United States
Anonymous traveller
The price is €201
includes taxes & fees
29 Sept - 30 Sept
Prime Loft of Main Street
A row of multi-story buildings with commercial storefronts, including a cafe and a restaurant.

19. Historic Main Street Studio | Dog-Friendly

Historic Main Street Studio | Dog-Friendly
St. Charles Historic District
9.2 out of 10, Wonderful, (39 reviews)
"Had a wonderful stay. It was a Monday night so parking was very easy and the room was clean and comfortable. I would recommend this place 100% "
United States
Sarah C.
The price is €201
includes taxes & fees
29 Sept - 30 Sept
Historic Main Street Studio | Dog-Friendly
A modern living room with a spiral staircase, a brick wall, a dining area, and a gray sofa.

20. Historic Main St 2BR | Steps to Shops

Historic Main St 2BR | Steps to Shops
St. Charles Historic District
9.4 out of 10, Exceptional, (42 reviews)
"This property has a nice renovation while keeping a lot of its original character. Very clean and comfortable beds as well. The location couldn’t be better! We really enjoyed our stay."
United States
William O.
The price is €363
includes taxes & fees
30 Sept - 1 Oct
Historic Main St 2BR | Steps to Shops
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Defiance Hotel Reviews

Drury Plaza Hotel St. Louis Creve Coeur

Drury Plaza Hotel St. Louis Creve Coeur

10/10 Excellent
"This Drury is a little more dated than others in the area, but the room was clean and was great for our needs."
Tonya 1-night trip
Posted 3 hours ago
Drury Plaza Hotel St. Louis Creve Coeur

Find out more about Defiance

Defiance Apartments information

Number of reviews
421
Accommodation
111 Apartments
Lowest Price
€59
Highest Price
€459

Frequently asked questions

What's it like to stay at an apartment in Defiance?
You'll find 10 apartments to choose from in Defiance for your holiday.
Why would you choose apartments instead of traditional hotels?
An apartment is often more spacious than a traditional hotel room and comes with a kitchen, so you can cook some of your meals. Apartments are ideal for families who want the conveniences of home, and also for couples who want to stay away from the tourist areas.
What's the top apartment I should consider for a stay in Defiance?
Here are some of the top apartments in the area: 2 Queen Beds | Non-Smoking, Kitchen: Situated in Maryland Heights , 18.7 mi/30.1 km from the heart of Defiance. Includes free WiFi and a Smart TV . 1 Queen Bed | Non-Smoking, Kitchen, Sofa-Bed: Located 18.7 mi/30.1 km away in Maryland Heights . Free WiFi and a Smart TV are included . The Lofts of North Main Street: Located in St. Charles , 19.2 mi/30.8 km away. Includes free WiFi, a sofa bed and a Smart TV . Access to on-site laundry facilities is available on site . Driftwood Den | Boho 2BR | Dog-Friendly: 19 mi/30.6 km away in St. Charles . Amenities include free WiFi . Historic Main Street Studio | Dog-Friendly: It's situated in St. Charles , 19.1 mi/30.8 km from Defiance.
How many apartments will I find in Defiance?
Expedia has 10 apartments to book in Defiance.
What can I expect from the weather in Defiance?
Weather is only one factor, but it can really affect your travel plans, especially if you are planning a longer stay in Defiance. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Defiance is 1228 mm.
What are the must-see places to visit in Defiance?
August A. Busch Memorial Conservation Area and Missouri River are a couple of scenic spots to enjoy the outdoors, whereas Historic Daniel Boone Home and Heritage Center is one of the cultural attractions. While here, Yellow Farmhouse Winery and Chandler Hill Vineyards are other places worth a visit.
What's the best way to get to and around Defiance?
Knowing a bit about the transportation options can you save you a headache when you get to your destination. Fly into St. Louis, MO (SUS-Spirit of St. Louis), which is located 7.5 mi (12 km) from the heart of the city. Otherwise, look for flights into Lambert-St. Louis International Airport (STL), which is 23.5 mi (37.8 km) away. If you'd like to explore around the area, consider renting a car to explore more sights.