Depew Hotels

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Property class

Top 10 trending Depew hotels

M Hotel Buffalo

3.5 star property
7.4 out of 10, Good, (1848)
"Nice place to stay"
The price is €97
includes taxes & fees
7 Aug - 8 Aug
M Hotel Buffalo

Comfort Inn University

2.5 star property
8.0 out of 10, Very good, (1011)
"Great stay"
The price is €110
includes taxes & fees
3 Sept - 4 Sept
Comfort Inn University

Lockport Inn & Suites

2.0 star property
9.2 out of 10, Wonderful, (1004)
"It was a great place to stay with friendly staff, nice pool, and comfortable room"
The price is €97
includes taxes & fees
5 Aug - 6 Aug
Lockport Inn & Suites

Sleep Inn

2.5 star property
8.8 out of 10, Excellent, (1104)
"Great place to stay"
The price is €103
includes taxes & fees
24 Aug - 25 Aug
Sleep Inn

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 star property
8.8 out of 10, Excellent, (1322)
"We enjoyed our stay"
The price is €124
includes taxes & fees
4 Sept - 5 Sept
Holiday Inn Express Grand Island - Niagara Falls by IHG

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 star property
8.0 out of 10, Very good, (1449)
"It’s good place to stay"
The price is €86
includes taxes & fees
1 Sept - 2 Sept
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Place Buffalo/Amherst

3.0 star property
9.0 out of 10, Wonderful, (1040)
"Great location "
The price is €164
includes taxes & fees
1 Sept - 2 Sept
Hyatt Place Buffalo/Amherst

Sleep Inn & Suites Buffalo Airport

2.5 star property
8.0 out of 10, Very good, (1653)
"This hotel is very comfy , bedroom super clean and shower very good , a lot parking available , staff super nice and friendly "
The price is €91
includes taxes & fees
3 Sept - 4 Sept
Sleep Inn & Suites Buffalo Airport

Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG

2.5 star property
8.8 out of 10, Excellent, (574)
"Comfortable and great staff."
The price is €136
includes taxes & fees
24 Aug - 25 Aug
Holiday Inn Express & Suites Tonawanda - Buffalo Area by IHG

Fairbridge Inn Express Buffalo Airport Williamsville

2.0 star property
4.6 out of 10, (1012)
"Hotel rooms are good, 10-12 min drive from downtown. "
The price is €62
includes taxes & fees
17 Aug - 18 Aug
Fairbridge Inn Express Buffalo Airport Williamsville

Wyndham Garden Buffalo Downtown

3.0 star property
9.0 out of 10, Wonderful, (1532)
"Rooms very small; breakfast was better than average Staff very pleasant. "
The price is €146
includes taxes & fees
10 Aug - 11 Aug
Wyndham Garden Buffalo Downtown

Garden Place Hotel

3.5 star property
7.8 out of 10, Good, (1813)
"Very photogenic place to stay. "
Garden Place Hotel

Buffalo Airport Hotel

3.0 star property
8.0 out of 10, Very good, (2580)
"It was a good place to stay."
The price is €79
includes taxes & fees
5 Aug - 6 Aug
Buffalo Airport Hotel

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3.0 star property
8.4 out of 10, Very good, (1878)
"It was a great stay "
The price is €97
includes taxes & fees
1 Sept - 2 Sept
La Quinta Inn & Suites by Wyndham Buffalo Amherst

Holiday Inn Express Cheektowaga North East by IHG

2.5 star property
8.4 out of 10, Very good, (1056)
"Nice location "
The price is €134
includes taxes & fees
1 Sept - 2 Sept
Holiday Inn Express Cheektowaga North East by IHG

Candlewood Suites Buffalo - Amherst by IHG

2.5 star property
8.6 out of 10, Excellent, (901)
"Staff was friendly, nice quiet and comfortable stay"
The price is €125
includes taxes & fees
24 Aug - 25 Aug
Candlewood Suites Buffalo - Amherst by IHG

Quality Inn Near Walden Galleria Mall

2.5 star property
8.0 out of 10, Very good, (1010)
"The lady at the front desk was amazing! "
The price is €108
includes taxes & fees
11 Aug - 12 Aug
Quality Inn Near Walden Galleria Mall

Extended Stay America Suites - Buffalo - Airport

2.5 star property
7.4 out of 10, Good, (783)
"Great place to stay. "
The price is €84
includes taxes & fees
13 Aug - 14 Aug
Extended Stay America Suites - Buffalo - Airport

Days Inn by Wyndham Tonawanda/Buffalo

2.0 star property
6.0 out of 10, (817)
"I loved this hotel! Excellent experience "
The price is €100
includes taxes & fees
1 Sept - 2 Sept
Days Inn by Wyndham Tonawanda/Buffalo

DoubleTree by Hilton Hotel Buffalo - Amherst

4.0 star property
7.8 out of 10, Good, (1005)
"Loved this hotel!"
The price is €124
includes taxes & fees
1 Sept - 2 Sept
DoubleTree by Hilton Hotel Buffalo - Amherst
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Near an Attraction

Learn more about Depew

Escape to romantic Depew! Enjoy its dining, sports and waterfalls.

Top Depew Hotel Reviews

Frequently asked questions

What's the best place for a stay in Depew?

Located 8.6 mi (13.9 km) from the heart of Depew, Hyatt Regency Buffalo / Hotel and Conference Center is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are M Hotel Buffalo and Buffalo Airport Hotel. See all available top hotels, or vacation rentals in Depew.

What are some of the best holiday rentals that Depew has to offer?

4BR 1.5BA Electric Vehicle Charger~25min Falls: This holiday home rental outside of Depew offers a balcony, a garden and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Make the most of billiards or a pool table in this rental home to help you unwind. See all vacation rentals in Depew.

If I need to cancel my hotel reservation in Depew, will I receive a refund?

Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.

What's the best budget-friendly accommodation in Depew?

Based on our traveller reviews, Pink Fountain Motor Inn is a top choice for a less expensive stay. View all budget hotels in Depew.

What's the best accommodation for a couple visiting Depew?

Pink Fountain Motor Inn is a favourite property for couples, and features cable TV and free WiFi. See all romantic hotels in Depew.

What are some accommodation options with pools in Depew?

Hyatt Regency Buffalo / Hotel and Conference Center: Hotel located near KeyBank Center. Features complimentary wireless Internet access, an indoor pool and a 24-hour fitness centre. M Hotel Buffalo and La Quinta Inn & Suites by Wyndham Buffalo Amherst are a couple of other choices that offer an on-site pool. View all hotels with pools in Depew.

What is the best spa hotel in Depew?

Pink Fountain Motor Inn is a top spa hotel with 14 rooms, free WiFi and free self-parking. Kick back and relax in the hot tub.

What is staying in Depew like?

Visitors can enjoy all that Depew has to offer, including the shopping, restaurants and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 12 hotels and other accommodation options to choose from. Find out more about Depew.

What should I see while I'm in Depew?

Places to visit in the wider area include Walden Galleria Mall, Samuel’s Grande Manor and Glen Falls. You'll also find Eastern Hills Mall and Broadway Market in the area. Take a look at what more there is to see and do in Expedia's Depew guide.

How can I get around Depew?

If you want to explore the larger area, hop on a train at Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.

What's the seasonal weather like in Depew?

The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Depew are January, March, February and December, with each month seeing an average of 43 cm of snowfall.