Depew Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
1 Dec - 2 Dec
Tomorrow
2 Dec - 3 Dec
This weekend
5 Dec - 7 Dec
Next weekend
12 Dec - 14 Dec

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending Depew hotels

Reception
Garden Place Hotel

Garden Place Hotel

3.5 star property
Buffalo
7.8 out of 10, Good, (2115)
"Clean room easy parking friendly staff"
United States
Janet
The price is €75
includes taxes & fees
2 Dec - 3 Dec
Garden Place Hotel
Lobby
Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

2.5 star property
Buffalo
8.0 out of 10, Very good, (1867)
"Nice stay!"
United States
Justin
The price is €67
includes taxes & fees
8 Dec - 9 Dec
Sleep Inn & Suites Buffalo Airport
Reception hall
M Hotel Buffalo

M Hotel Buffalo

3.5 star property
Buffalo
7.4 out of 10, Good, (2498)
"Clean rooms, good breakfast, check in process was quick."
United States
Chris
The price is €68
includes taxes & fees
2 Dec - 3 Dec
M Hotel Buffalo
Indoor pool
Hyatt Regency Buffalo / Hotel and Conference Center

Hyatt Regency Buffalo / Hotel and Conference Center

3.5 star property
Downtown Buffalo
8.2 out of 10, Very good, (1656)
"Everything was great including the location to downtown. "
Canada
Louise
The price is €105
includes taxes & fees
2 Dec - 3 Dec
Hyatt Regency Buffalo / Hotel and Conference Center
Exterior
Hampton Inn Buffalo - Amherst, NY

Hampton Inn Buffalo - Amherst, NY

2.5 star property
Buffalo
9.4 out of 10, Exceptional, (1981)
"Clean room, comfy bed, great staff and nice breakfast "
United States
Jose
The price is €101
includes taxes & fees
8 Dec - 9 Dec
Hampton Inn Buffalo - Amherst, NY
Lobby
Comfort Inn University

Comfort Inn University

2.5 star property
Buffalo
8.0 out of 10, Very good, (1196)
"Good place to stay and rest "
United States
Luis
The price is €101
includes taxes & fees
22 Dec - 23 Dec
Comfort Inn University
Exterior
La Quinta Inn by Wyndham Buffalo Airport

La Quinta Inn by Wyndham Buffalo Airport

3.0 star property
Buffalo
8.0 out of 10, Very good, (1353)
"Clean room and very nice and helpful staff! "
United States
Michelle
The price is €78
includes taxes & fees
8 Dec - 9 Dec
La Quinta Inn by Wyndham Buffalo Airport
Premium bedding, in-room safe, desk, blackout curtains
Holiday Inn Express Grand Island - Niagara Falls by IHG

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 star property
Grand Island
8.8 out of 10, Excellent, (1572)
"Room was clean, location was great and the breakfast was very good! "
United States
Karen
The price is €60
includes taxes & fees
19 Dec - 20 Dec
Holiday Inn Express Grand Island - Niagara Falls by IHG
Indoor pool
Sleep Inn Amherst - Buffalo North near University

Sleep Inn Amherst - Buffalo North near University

2.5 star property
Buffalo
8.8 out of 10, Excellent, (1146)
"Staff is friendly, stores close.by, and hot tub was bubbly"
United States
Tina
The price is €86
includes taxes & fees
30 Dec - 31 Dec
Sleep Inn Amherst - Buffalo North near University
Exterior
Hyatt Place Buffalo/Amherst

Hyatt Place Buffalo/Amherst

3.0 star property
Buffalo
9.0 out of 10, Wonderful, (1099)
"Great hotel and in close proximity to Himark Stadium for game day; Gallaria Mall for shopping and other fun areas to visit. Will definitely stay again!"
United States
Suzanna
The price is €152
includes taxes & fees
11 Dec - 12 Dec
Hyatt Place Buffalo/Amherst
Courtyard view
Buffalo Airport Hotel

Buffalo Airport Hotel

3.0 star property
Buffalo
8.0 out of 10, Very good, (2770)
"Would stay there again."
United States
Kell
The price is €71
includes taxes & fees
9 Dec - 10 Dec
Buffalo Airport Hotel
Free daily continental breakfast
Quality Inn Near Walden Galleria Mall

Quality Inn Near Walden Galleria Mall

2.5 star property
Buffalo
8.0 out of 10, Very good, (1037)
"Staff were great,room was clean and the location of the hotel was convenient. "
United States
Sean
The price is €83
includes taxes & fees
3 Dec - 4 Dec
Quality Inn Near Walden Galleria Mall
Lobby
La Quinta Inn & Suites by Wyndham Buffalo Amherst

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3.0 star property
Buffalo
8.6 out of 10, Excellent, (1961)
"Very clean facility, beds were comfortable, good shower pressure and hot water"
United States
Michael
The price is €79
includes taxes & fees
8 Dec - 9 Dec
La Quinta Inn & Suites by Wyndham Buffalo Amherst
2 restaurants, dinner served
The Delavan Hotel & Spa

The Delavan Hotel & Spa

4.0 star property
Bowmansville
8.8 out of 10, Excellent, (1012)
"The food & bar are top notch. "
United States
Matthew
The Delavan Hotel & Spa
Lobby
Hotel at the Lafayette Trademark Collection by Wyndham

Hotel at the Lafayette Trademark Collection by Wyndham

3.5 star property
Downtown Buffalo
8.6 out of 10, Excellent, (1007)
"Nice place "
United States
Glen
The price is €102
includes taxes & fees
23 Dec - 24 Dec
Hotel at the Lafayette Trademark Collection by Wyndham
Lobby
Wyndham Garden Buffalo Downtown

Wyndham Garden Buffalo Downtown

3.0 star property
Downtown Buffalo
9.0 out of 10, Wonderful, (1709)
"Staff was great Nice breakfast "
United States
Kathleen
The price is €124
includes taxes & fees
8 Dec - 9 Dec
Wyndham Garden Buffalo Downtown
Property entrance
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2.5 star property
Buffalo
8.2 out of 10, Very good, (1014)
"The staff was awesome, our room was clean and all around it made our vacation for the location and friendly people. "
Canada
Brenda
The price is €86
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG
Exterior
Hampton Inn & Suites Buffalo Downtown

Hampton Inn & Suites Buffalo Downtown

2.5 star property
Downtown Buffalo
8.8 out of 10, Excellent, (1012)
"Great location. Parking available. Good breakfast. "
United States
Carmen
The price is €128
includes taxes & fees
11 Dec - 12 Dec
Hampton Inn & Suites Buffalo Downtown
Desk, blackout curtains, iron/ironing board, free cots/infant beds
Best Western Galleria Inn & Suites

Best Western Galleria Inn & Suites

2.5 star property
Buffalo
6.6 out of 10, (1008)
"Very clean and new looking.very nice breakfast area with many options.Would definitely stay again. "
United States
Martina
The price is €83
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Galleria Inn & Suites
Exterior
Holiday Inn Express Cheektowaga North East by IHG

Holiday Inn Express Cheektowaga North East by IHG

2.5 star property
Buffalo
8.4 out of 10, Very good, (1206)
"Great place"
United States
James
The price is €93
includes taxes & fees
9 Dec - 10 Dec
Holiday Inn Express Cheektowaga North East by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Depew Hotel Reviews

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

10/10 Excellent
"I was great the room was clean "
Vidal 4-night trip
Posted 14 hours ago
Sleep Inn & Suites Buffalo Airport

More cheap stays in Depew

Sleep Inn & Suites Buffalo Airport

Sleep Inn & Suites Buffalo Airport

100 Holtz Dr Buffalo NY
The price is €67 per night from 8 Dec to 9 Dec
€67
8 Dec - 9 Dec
includes taxes & fees
7.8/10 Good! (1,864 reviews)

Frequently asked questions

What's the best place for a stay in Depew?
Located 8.6 mi (13.9 km) from the heart of Depew, Hyatt Regency Buffalo / Hotel and Conference Center is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Garden Place Hotel and Buffalo Airport Hotel. See all available top hotels, or vacation rentals in Depew.
What are some of the best holiday rentals that Depew has to offer?
Cozy Buffalo Getaway – Minutes to Downtown & Bills Stadium: This holiday home rental outside of Depew has air conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Depew.
If I need to cancel my hotel reservation in Depew, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.
What are some accommodation options with pools in Depew?
Hyatt Regency Buffalo / Hotel and Conference Center: Hotel located near KeyBank Center. Features complimentary wireless Internet access, an indoor pool and a 24-hour fitness centre. M Hotel Buffalo and Days Inn & Suites by Wyndham Niagara Falls/Buffalo are a couple of other choices that offer an on-site pool. View all hotels with pools in Depew.
What is staying in Depew like?
Visitors can enjoy all that Depew has to offer, including the shopping, restaurants and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 12 hotels and other accommodation options to choose from. Find out more about Depew.
What should I see while I'm in Depew?
Places to visit in the wider area include Holiday Twin Rinks, Walden Galleria Mall and Samuel's Grande Manor. You'll also find Glen Falls and Buffalo Central Terminal in the area. Take a look at what more there is to see and do in Expedia's Depew guide.
How can I get around Depew?
If you want to explore the larger area, hop on a train at Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.
What's the seasonal weather like in Depew?
The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Depew are January, March, February and December, with each month seeing an average of 43 cm of snowfall.

Explore a world of travel with Expedia