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Our top choices for Audrain County hotels

Exterior
Best Western Teal Lake Inn

Best Western Teal Lake Inn

Best Western Teal Lake Inn
2.5 star property
Mexico
8.4 out of 10, Very good, (483)
"It was a great stay and very quiet. The restful sleep was enjoyable."
United States
Eric
The price is €79
includes taxes & fees
11 Jan - 12 Jan 2026
Best Western Teal Lake Inn
Indoor pool
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
2.5 star property
Mexico
5.6 out of 10, (383)
"Staff were very friendly and accommodating. Room was very clean and comfortable!"
United States
Rusty
Capital O Amerihost Inn and Suites Mexico Hwy 54 MO
Exterior
Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico
2.0 star property
Mexico
7.0 out of 10, Good, (296)
"Comfortable bed... Didn't like stool loose on base."
United States
Marvin
The price is €73
includes taxes & fees
11 Jan - 12 Jan 2026
Days Inn by Wyndham Mexico
Reception
Budget Inn Mexico MO on US 54

Budget Inn Mexico MO on US 54

Budget Inn Mexico MO on US 54
2.0 star property
Mexico
7.0 out of 10, Good, (110)
"Great "
United States
Jedrzej
The price is €81
includes taxes & fees
11 Jan - 12 Jan 2026
Budget Inn Mexico MO on US 54
Fridge, microwave, oven, stovetop
Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake

Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake

Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake
2.0 star property
Paris
8.8 out of 10, Excellent, (5)
"The cabin was very clean and the Host was very nice and helpful."
United States
TREY
The price is €222
includes taxes & fees
11 Jan - 12 Jan 2026
Rustic 2-bedroom cabin next to 1000+ acre Conservation area near Mark Twain Lake
House (1 Bedroom) | Interior
'grace Place' Clark House on Farm: Shared Hot Tub!

'grace Place' Clark House on Farm: Shared Hot Tub!

'grace Place' Clark House on Farm: Shared Hot Tub!
3.0 star property
Clark
10.0 out of 10, Exceptional, (2)
"Very clean with a wonderful country atmosphere. Perfect size for 1-2 people to share. The farm animals won my heart over!!!!!!!"
United States
Becky
'grace Place' Clark House on Farm: Shared Hot Tub!
Interior
Sisters Four Bed and Bath - Luxury living in a small town atmosphere!

Sisters Four Bed and Bath - Luxury living in a small town atmosphere!

Sisters Four Bed and Bath - Luxury living in a small town atmosphere!
Centralia
10.0 out of 10, Exceptional, (33)
"Clean, beautiful property for family to stay in."
United States
Janine V.
Sisters Four Bed and Bath - Luxury living in a small town atmosphere!
Apartment (2 Bedrooms) | Front of property
'kimberly's Hope' Clark Apt on Farm w/ Pool Access

'kimberly's Hope' Clark Apt on Farm w/ Pool Access

'kimberly's Hope' Clark Apt on Farm w/ Pool Access
3.0 star property
Clark
'kimberly's Hope' Clark Apt on Farm w/ Pool Access
House (2 Bedrooms) | Interior
Historic Clark Cabin w/ Deck & Fishing Pond Access

Historic Clark Cabin w/ Deck & Fishing Pond Access

Historic Clark Cabin w/ Deck & Fishing Pond Access
3.0 star property
Clark
Historic Clark Cabin w/ Deck & Fishing Pond Access
Interior
Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods

Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods

Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods
Thompson
10.0 out of 10, Exceptional, (15)
"Nice cabin in quiet woods with a pond."
United States
Mary
Rut & Strut Ranch - 35 minutes from Mark Twain Lake! Quiet Cabin in the woods
Outdoor dining
Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO

Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO

Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO
Centralia
10.0 out of 10, Exceptional, (154)
"Always wonderful staying at the Rollins House Inn! "
United States
Syndy D.
Tastefully restored historic home in quaint town, 20 minute drive to Columbia MO
Pool
Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.

Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.

Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.
2.0 star property
Mexico
10.0 out of 10, Exceptional, (12)
"This was our 3rd stay, and it was amazing again! "
United States
Bert and Naomi W.
Relax fish/play: Pvt 25-acre clear Blue Lake w/ home that sleeps 10 comfortably.
Non-Smoking
America's Value Inn Mexico

America's Value Inn Mexico

America's Value Inn Mexico
1.5 star property
Mexico
5.4 out of 10, (19)
"who ever owns this property I met him ,seems to be very humble. He needs to update this property . i dont mind paying more if everything is well maintained and welcoming. "
United States
Sopan
America's Value Inn Mexico
Dining
Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO

Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO

Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO
Centralia
10.0 out of 10, Exceptional, (45)
"I loved the process for reserving the room. Also, the property was clean and provided what we needed for the event. This is an excellent home to rent!"
United States
Ieti F.
Beautiful historic home in downtown Centralia, just 20 minutes from Columbia, MO
House (3 Bedrooms) | Interior
Dog-friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-friendly Cabin w/ Yard Near Auxvasse Creek!
3.0 star property
Kingdom City
Dog-friendly Cabin w/ Yard Near Auxvasse Creek!
Exterior
Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths

Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths

Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths
Auxvasse, MO
10.0 out of 10, Exceptional, (30)
"This is an absolutely beautiful home in a tranquil setting. We have stayed in many rentals and this one outshines them all in every area!!"
United States
Angela B.
Two-House Private Country Retreat - 4 Bedrooms and 3.5 Baths
Dining
Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek

Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek

Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek
2.0 star property
Kingdom City
9.6 out of 10, Exceptional, (10)
"Beautiful location "
United States
Scott H.
Retreat on the Creek: Home overlooking a backyard lake and the Auxvasse Creek
Microwave, dishwasher, coffee/tea maker, toaster
Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!

Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!
2.0 star property
Kingdom City
Dog-Friendly Cabin w/ Yard Near Auxvasse Creek!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Audrain County Hotel Reviews

Wingate by Wyndham - Columbia

Wingate by Wyndham - Columbia

10/10 Excellent
"Online check-in was smooth and appreciated by front desk staff. Clean room and beautiful clean lobby and the breakfast was above average. Will stay there again."
Kim 1-night trip
Posted 3 days ago
Wingate by Wyndham - Columbia

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