Search Perry County Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
20 Dec - 21 Dec
Tomorrow
21 Dec - 22 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Perry County hotels

Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (541)
"Clean room and pleasant staff"
United States
David
The price is €85
includes taxes & fees
25 Dec - 26 Dec
Holiday Inn Express & Suites Perryville by IHG
Exterior
Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville

Super 8 by Wyndham Perryville
2.0 star property
Perryville
8.4 out of 10, Very good, (941)
"The room was spotless, and the staff was extremely patient. Each one was very helpful. It was easy to get a good night's sleep - the building was very quiet."
United States
Cynthia
The price is €62
includes taxes & fees
28 Dec - 29 Dec
Super 8 by Wyndham Perryville
Lobby
Quality Inn Perryville I-55

Quality Inn Perryville I-55

Quality Inn Perryville I-55
2.5 star property
Perryville
6.6 out of 10, (124)
"Nice place would recommend Mary Jane’s if you’re looking for good food "
United States
Andrew
The price is €68
includes taxes & fees
28 Dec - 29 Dec
Quality Inn Perryville I-55
Seasonal outdoor pool
Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville

Days Inn by Wyndham Perryville
2.0 star property
Perryville
6.8 out of 10, (415)
"Was a nice place."
United States
Lesliee
The price is €61
includes taxes & fees
23 Dec - 24 Dec
Days Inn by Wyndham Perryville
Exterior
Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin
Perryville
9.8 out of 10, Exceptional, (8)
"Property was excellent house was really nice and in a great location would stay there again for sure "
United States
David R.
Hot Tub & Creek Views: Secluded Perryville Cabin
Property grounds
The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!

The Weber Farm - Enjoy a beautiful 100 acre farm!
Frohna
10.0 out of 10, Exceptional, (32)
"Hosts were great. I just wish they had a second bath or atleast a larger bathroom. "
United States
Dennis H.
The price is €133
includes taxes & fees
22 Dec - 23 Dec
The Weber Farm - Enjoy a beautiful 100 acre farm!
Property grounds
TreeLoft at BaseCamp

TreeLoft at BaseCamp

TreeLoft at BaseCamp
2.0 star property
Perryville
10.0 out of 10, Exceptional, (5)
"This place is perfect if you want a private upscale experience that is immersed in natural beauty. The treehouse is luxurious and so comfortable. We loved every minute of our stay. "
United States
joel r.
TreeLoft at BaseCamp
Interior
Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant

Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant
Perryville
10.0 out of 10, Exceptional, (1)
"Everything was perfect!"
United States
Thor L.
The price is €277
includes taxes & fees
21 Dec - 22 Dec
Urban Loft #1 RED · Urban Loft Downtown above BrewCo & Restaurant
Interior
Gorgeous, downtown house!

Gorgeous, downtown house!

Gorgeous, downtown house!
Perryville
10.0 out of 10, Exceptional, (1)
"Our stay was excellent and our host Carisa was a Great person to work with. The house was beautiful. The house worked out great for us. We had 6 people staying and we all had very comfortable beds and our own bathrooms. Great for a large family. "
United States
Doyle or Cheryl D.
The price is €766
includes taxes & fees
22 Dec - 23 Dec
Gorgeous, downtown house!
House (3 Bedrooms) | Interior
Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin

Hot Tub & Creek Views: Secluded Perryville Cabin
3.0 star property
Perryville
Hot Tub & Creek Views: Secluded Perryville Cabin
Dining
Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.

Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.

Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.
Saint Mary
9.8 out of 10, Exceptional, (7)
"Large space which was great. Big bedrooms. "
United States
Robin
Peaceful 4BR ranch w/ hot tub, fire pit & quick access to Ste. Genevieve’s wineries & shops.
House (Multiple Bedrooms) | Interior
Missouri Castle w/ Private Lake, Pool & 100 Acres!

Missouri Castle w/ Private Lake, Pool & 100 Acres!

Missouri Castle w/ Private Lake, Pool & 100 Acres!
3.0 star property
St Mary
Missouri Castle w/ Private Lake, Pool & 100 Acres!
55-inch Smart TV with digital channels, TV, streaming services
Urban Lofts

Urban Lofts

Urban Lofts
3.0 star property
Perryville
9.2 out of 10, Wonderful, (17)
"Great place to stay! "
United States
Eric
Urban Lofts
1 bedroom, desk, iron/ironing board, WiFi
Downtown Loft w/ Amazing Bath Tub & Shower

Downtown Loft w/ Amazing Bath Tub & Shower

Downtown Loft w/ Amazing Bath Tub & Shower
Perryville
10.0 out of 10, Exceptional, (6)
"Amazing place. "
United States
Brandy P.
Downtown Loft w/ Amazing Bath Tub & Shower
House (0 Bedroom) | Interior
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!

'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
3.0 star property
Perryville
10.0 out of 10, Exceptional, (2)
"The house and host were just awesome, enjoyed our stay Toni even helped me Extend!! Would def stay again:)"
United States
Shandese
'the Brewer Guesthouse' Tiny Home w/ Patio & Yard!
Property grounds
Historic House in heart of Altenburg

Historic House in heart of Altenburg

Historic House in heart of Altenburg
2.0 star property
Altenburg
10.0 out of 10, Exceptional, (1)
"Great place to stay Quite and clean"
United States
Catherine M.
Historic House in heart of Altenburg
Microwave, oven, stovetop, dishwasher
Tranquil and relaxing living quarters surrounded by nature.

Tranquil and relaxing living quarters surrounded by nature.

Tranquil and relaxing living quarters surrounded by nature.
2.0 star property
Frohna
Tranquil and relaxing living quarters surrounded by nature.
Outdoor spa tub
New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp

New! Luxury Meets Nature - TreeRise at BaseCamp
2.0 star property
Perryville
10.0 out of 10, Exceptional, (1)
"Our visit was short but so special. Waylon and Kaci have created a sweet haven of rest in the woods of Missouri. We so appreciated the chance to unplug for a bit. Can’t recommend enough! "
United States
Amber S.
The price is €434
includes taxes & fees
23 Dec - 24 Dec
New! Luxury Meets Nature - TreeRise at BaseCamp
Fridge, microwave, stovetop, coffee/tea maker
'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!

'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!

'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!
Perryville
10.0 out of 10, Exceptional, (9)
"Clean, quiet, and conveniently located near Perryville. I would definitely stay again."
United States
Matthew
'The Brewer Guesthouse' Tiny Home w/ Patio & Yard!
Exterior
Downtown Urban Loft above Restaurants

Downtown Urban Loft above Restaurants

Downtown Urban Loft above Restaurants
2.0 star property
Perryville
The price is €273
includes taxes & fees
21 Dec - 22 Dec
Downtown Urban Loft above Restaurants
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Perry County Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Didn’t eat the breakfast but I’m sure it is wonderful. Everything from the Check in process to the condition of the rooms to the comfort of the stay was worth the money "
Corrie 1-night trip
Posted 3 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

Explore a world of travel with Expedia