A large lake surrounded by dense forests.

Seneca Hotel Guide. Hotels in Downtown, Seneca, United States of America

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Check prices for these dates

Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

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Our top choices for Downtown hotels

A restaurant interior with a counter, seating area, and a TV mounted on the wall.

1. Quality Inn Seneca US-123

Quality Inn Seneca US-123
2.5 star property
3.8 km from Downtown
8.0 out of 10, Very good, (763 reviews)
"Clean rooms clean parking area nice staff all good"
United States
Barry
The price is €89
includes taxes & fees
3 Nov - 4 Nov
Quality Inn Seneca US-123
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.

2. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
1.7 km from Downtown
8.4 out of 10, Very good, (694 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
The price is €92
includes taxes & fees
26 Oct - 27 Oct
Best Western Seneca-Clemson
A hotel dining area with a long table, multiple chairs, and a bar in the background.

3. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
2.2 km from Downtown
9.2 out of 10, Wonderful, (762 reviews)
"Room was clean and staff was friendly and helpful."
United States
Sasha
The price is €132
includes taxes & fees
25 Oct - 26 Oct
Hampton Inn & Suites Seneca-Clemson Area
A poolside area with outdoor seating and a view of a lake and forested hills.

4. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (288 reviews)
"Excellent in every way!"
United States
Bonnie
The price is €118
includes taxes & fees
8 Nov - 9 Nov
Fairfield Inn & Suites Seneca Clemson Univ Area
An outdoor patio area with a fire pit, seating, and string lights.

5. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (900 reviews)
"Great stay!"
United States
Melissa
The price is €100
includes taxes & fees
19 Nov - 20 Nov
Tru by Hilton Seneca Clemson
A modern dining area with a high ceiling, large windows, and a buffet setup.

6. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (789 reviews)
"Staff were nice and accommodating"
United States
Rosario
The price is €72
includes taxes & fees
27 Oct - 28 Oct
Days Inn by Wyndham Seneca / Clemson Area
A multi-story hotel with a swimming pool, landscaped grounds, and a parking area.

7. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,004 reviews)
"Friendly front desk and bar staff. We had a really nice overnight stay."
United States
Sherry
The price is €121
includes taxes & fees
27 Oct - 28 Oct
Lakeside Lodge Clemson
A cabin with a cozy interior, a wooden exterior, and a view of the forest.

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
7.5 km from Downtown
9.8 out of 10, Exceptional, (115 reviews)
"My wife and I enjoyed our stay here. 10/10 experience."
United States
Winston
The price is €130
includes taxes & fees
3 Nov - 4 Nov
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
A reception area with a reception desk, a sofa, a staircase, and a wall with artwork.

9. Inn @ Clemson

Inn @ Clemson
2.5 star property
11.6 km from Downtown
8.0 out of 10, Very good, (1,005 reviews)
"Clean room, comfortable beds, good breakfast, great price!"
United States
Kristi
The price is €79
includes taxes & fees
25 Oct - 26 Oct
Inn @ Clemson
A spacious indoor dining area with multiple tables and chairs, a food service counter, and a modern architectural design with balconies.

10. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.0 out of 10, Very good, (1,003 reviews)
"Great place to stay while visiting your kids at Clemson!"
United States
Angela
The price is €104
includes taxes & fees
3 Nov - 4 Nov
Best Western Plus Clemson Hotel & Conference Center
A modern bar area with a menu board, bar stools, and a countertop with various items.

11. Courtyard Marriott Clemson

Courtyard Marriott Clemson
3.0 star property
12.9 km from Downtown
9.0 out of 10, Wonderful, (591 reviews)
"The staff were so friendly and accommodating. The property was very clean and room was spacious."
United States
kim
The price is €102
includes taxes & fees
22 Nov - 23 Nov
Courtyard Marriott Clemson
A dining area with a table and chairs, large windows with a view of the outside, and a green sofa.

12. Days Inn by Wyndham Clemson

Days Inn by Wyndham Clemson
3.5 star property
12.5 km from Downtown
6.8 out of 10, (236 reviews)
"While the hotel is close to Clemson, the property/ rooms were GROSS!! The bathroom had been wiped down, but whoever cleaned it missed the soap and shampoo left up top on the rim. The AC smelt so strongly of mildew/ mold that we could NOT turn it on. The whole room smelled like wet towels"
United States
Stephanie
The price is €79
includes taxes & fees
25 Oct - 26 Oct
Days Inn by Wyndham Clemson
A modern kitchen area with a bar counter and seating.

13. Hampton Inn Clemson-University Area

Hampton Inn Clemson-University Area
2.5 star property
9.8 km from Downtown
8.8 out of 10, Excellent, (651 reviews)
"Staff was great especially Crystal. Breakfast was fine. A little hidden by trees so watch out or you could miss entrance. Also, driveway just a little steep to get into lot but once there everything was fine. "
United States
Blaise
The price is €96
includes taxes & fees
22 Nov - 23 Nov
Hampton Inn Clemson-University Area
A hotel lobby with a reception desk, a large tiger mural, a TV, and a seating area with a blue sofa.

14. Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.4 out of 10, Very good, (1,001 reviews)
"Updated room and friendly staff."
United States
Sherie
The price is €104
includes taxes & fees
15 Nov - 16 Nov
Comfort Inn & Suites Clemson - University Area
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.

15. The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (656 reviews)
"Very conveniently located to Clemson and well maintained. We enjoyed having an afternoon beverage at the bar and grabbing a quick bite to eat in the morning. Hallways were quiet and I appreciated the bathroom amenities and robes too. I would definitely recommend staying here."
United States
Amy
The price is €151
includes taxes & fees
15 Nov - 16 Nov
The Abernathy of Clemson
A Holiday Inn Express hotel with a stone facade, large windows, and a parking lot.

16. Holiday Inn Express & Suites Clemson by IHG

Holiday Inn Express & Suites Clemson by IHG
2.5 star property
12.4 km from Downtown
8.8 out of 10, Excellent, (998 reviews)
"Wonderful place to stay."
United States
John
The price is €128
includes taxes & fees
25 Oct - 26 Oct
Holiday Inn Express & Suites Clemson by IHG
A golf course with a water body, trees, and a distant view of a bridge.

17. Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,004 reviews)
"Great property!"
United States
Lilllian
The price is €148
includes taxes & fees
25 Oct - 26 Oct
Clemson University's James F. Martin Inn
A kitchen with a coffee maker, microwave, and refrigerator.

18. Rodeway Inn & Suites Walhalla

Rodeway Inn & Suites Walhalla
2.0 star property
12.8 km from Downtown
7.6 out of 10, Good, (198 reviews)
"Good value for the price. Bed was comfortable and the price was good"
United States
Richard
The price is €80
includes taxes & fees
23 Nov - 24 Nov
Rodeway Inn & Suites Walhalla
A hotel lobby with a reception desk, seating area, and a view of the street outside.

19. Econo Lodge Clemson - University Area

Econo Lodge Clemson - University Area
2.0 star property
13.1 km from Downtown
7.2 out of 10, Good, (160 reviews)
"Good location . Good price. Nice and quiet. Unusually good tv show choices. (Much better than last 4 or 5 hotels that I stayed at!)"
United States
Ruth
The price is €80
includes taxes & fees
25 Oct - 26 Oct
Econo Lodge Clemson - University Area
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.

20. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (901 reviews)
"Always a wonderful stay!"
United States
Laurrie
The price is €207
includes taxes & fees
3 Nov - 4 Nov
The Shepherd Hotel Downtown Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Downtown

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A poolside area with outdoor seating and a view of a lake and forested hills.
Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
9.4
Exceptional
288 reviews
View
A hotel dining area with a long table, multiple chairs, and a bar in the background.
Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
9.2
Wonderful
762 reviews
View
A hotel room with a bed, a desk, a chair, a large window with curtains, a bathroom with a bathtub, and a flat-screen TV.
Best Western Seneca-Clemson
2.5 star property
8.4
Very good
694 reviews
View
An outdoor patio area with a fire pit, seating, and string lights.
Tru by Hilton Seneca Clemson
2.5 star property
9.2
Wonderful
900 reviews
View
A restaurant interior with a counter, seating area, and a TV mounted on the wall.
Quality Inn Seneca US-123
2.5 star property
8.0
Very good
763 reviews
View

Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.
A sunset over a lake surrounded by dense forests and residential areas.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

A sunset over a calm lake with a kayaker and a large tree on the shore.

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit South Beach and Lake Keowee.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Oconee County Library Seneca Branch and Keowee Reservoir.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, Oconee County Library Seneca Branch and Keowee Reservoir are some notable places to visit nearby.

Top Downtown Hotel Reviews

The Inn at Patrick Square

The Inn at Patrick Square

10/10 Excellent
"Super nice!"
Kevin 1-night trip
Posted 21 hours ago
The Inn at Patrick Square

Frequently asked questions

What is Downtown like?
Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Oconee County Library Seneca Branch and Blue Ridge Arts Center as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
For your stay in Downtown, Historic Seneca Bungalow is one of the top choices based on our traveller data.
How many hotels will I be able to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 12 hotels and other accommodation options in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.
What can I see and do in this Seneca neighbourhood?
Oconee County Library Seneca Branch, Blue Ridge Arts Center and Seneca Historic District are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Bertha Lee Strickland Cultural Museum and The Gauntlet are some other places worth a visit. Seneca City Hall, Golden Corner Plaza and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Applewood Shopping Center or Wyndham Plaza.