Seneca Hotels

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Our top choices for Seneca hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (695 reviews)
"Very pleasant and helpful staff. Comfortable room though fairly small."
United States
William
The price is €85
includes taxes & fees
24 May - 25 May
Quality Inn Seneca Clemson Area US-123

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (222 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is €113
includes taxes & fees
3 May - 4 May
Fairfield Inn & Suites Seneca Clemson Univ Area

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (71 reviews)
"Great getaway!!!"
United States
Latoya
The price is €140
includes taxes & fees
4 May - 5 May
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,003 reviews)
"This place is tops! The area is great, rooms were wonderful, and amenities were amazing. Definitely plan on staying again asap!"
United States
Valarie Tina
The price is €115
includes taxes & fees
9 May - 10 May
Lakeside Lodge Clemson

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (655 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is €88
includes taxes & fees
13 May - 14 May
Best Western Seneca-Clemson

8 Mi to Clemson: Peaceful Family Home w/ Yard

8 Mi to Clemson: Peaceful Family Home w/ Yard
3.0 star property
Seneca
10.0 out of 10, Exceptional, (1 review)
"The place was all out perfect the owner was polite and perfect. It was a very peaceful place to stay thank you so much."
United States
Jason
The price is €330
includes taxes & fees
3 May - 4 May
8 Mi to Clemson: Peaceful Family Home w/ Yard

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (834 reviews)
"Great location and facilities"
United States
Brian
The price is €108
includes taxes & fees
24 May - 25 May
Tru by Hilton Seneca Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (739 reviews)
"Strong disinfectant smell in room. Beds and linens were very comfortable."
United States
Mary Jane
The price is €69
includes taxes & fees
30 Apr - 1 May
Days Inn by Wyndham Seneca / Clemson Area

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (700 reviews)
"Great staff and rooms were very clean."
United States
Austin
The price is €103
includes taxes & fees
24 May - 25 May
Hampton Inn & Suites Seneca-Clemson Area

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (812 reviews)
"Fantastic place and staff most accommodating "
United States
Walter
The price is €72
includes taxes & fees
29 Apr - 30 Apr
Baymont by Wyndham Easley/Greenville

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (427 reviews)
"Clean room Friendly Staff"
United States
Andrina
The price is €55
includes taxes & fees
23 May - 24 May
Quality Inn & Suites Easley - Greenville

Days Inn by Wyndham Easley/Greenville/Clemson Area

Days Inn by Wyndham Easley/Greenville/Clemson Area
2.0 star property
Easley
6.2 out of 10, (843 reviews)
"Room was clean and as described. No issues with AC or hot water. Th"
United States
Leah
The price is €61
includes taxes & fees
4 May - 5 May
Days Inn by Wyndham Easley/Greenville/Clemson Area

Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (835 reviews)
"Staff were so helpful , place was clean and food spots near by"
United States
osiry
The price is €107
includes taxes & fees
25 May - 26 May
Hampton Inn Anderson/ Alliance Business Park

Holiday Inn Express Anderson by IHG

Holiday Inn Express Anderson by IHG
2.5 star property
Anderson
8.4 out of 10, Very good, (392 reviews)
"Lots of construction but nice staff"
United States
Andrew
The price is €93
includes taxes & fees
27 May - 28 May
Holiday Inn Express Anderson by IHG

The Bleckley Inn

The Bleckley Inn
3.5 star property
Anderson
9.8 out of 10, Exceptional, (411 reviews)
"Staff was helpful, clean room comfortable bed!"
United States
charles
The price is €198
includes taxes & fees
29 Apr - 30 Apr
The Bleckley Inn

Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (238 reviews)
"Great room and staff and breakfast was great "
United States
reginald
The price is €136
includes taxes & fees
10 May - 11 May
Home2 Suites by Hilton Anderson Downtown

Horizon Inn & Suites

Horizon Inn & Suites
2.0 star property
Anderson
4.8 out of 10, (289 reviews)
"Holes in sheets, hair on towels, mold in showers. You get what you pay for but staff was great and friendly. Perfect for a quick and cheap stay"
United States
Kara
The price is €55
includes taxes & fees
29 Apr - 30 Apr
Horizon Inn & Suites

Super 8 by Wyndham Anderson/Clemson Area

Super 8 by Wyndham Anderson/Clemson Area
2.5 star property
Anderson
6.6 out of 10, (282 reviews)
"Everything was just great!"
United States
Lorrie
The price is €71
includes taxes & fees
29 Apr - 30 Apr
Super 8 by Wyndham Anderson/Clemson Area

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (915 reviews)
"Staff was great and our beds were very comfortable!"
United States
Laurie
The price is €55
includes taxes & fees
10 May - 11 May
Quality Inn Clemson near University

Holiday Inn Anderson by IHG

Holiday Inn Anderson by IHG
3.0 star property
Anderson
8.8 out of 10, Excellent, (724 reviews)
"Great hotel in all regards"
Canada
Dan
The price is €104
includes taxes & fees
3 May - 4 May
Holiday Inn Anderson by IHG
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Where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most.

Downtown

City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Lakeside Lodge Clemson is one of the top choices for your stay based on our traveller data. This hotel offers a restaurant and free parking. Other good options for your visit include Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy and Quality Inn Seneca Clemson Area US-123. See all available top hotels, or vacation rentals in Seneca.
What are some of the best holiday rentals that Seneca has to offer?
Charming and Entertaining Lake House Retreat for Large Groups!: This highly rated holiday home rental in Seneca offers 1 hot tub, a BBQ and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a stovetop and a microwave. Some other homes for rent in Seneca include Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock and 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly!. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Quality Inn Seneca Clemson Area US-123 and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Quality Inn Seneca Clemson Area US-123 and Hampton Inn & Suites Seneca-Clemson Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 305 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include Oconee Community Theatre and The Gauntlet. Natural beauty is on display at Lake Keowee, Lake Hartwell and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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