Seneca Hotels

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Our top choices for Seneca hotels

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (687 reviews)
"Everting was good"
United States
Susan
The price is €80
includes taxes & fees
15 Mar - 16 Mar
Quality Inn Seneca Clemson Area US-123

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (213 reviews)
"Hotel and room were super clean. Hotel is fairly new and it shows. Nice view of Lake Keowee. Breakfast was quite good & excellent coffee. Would definitely stay there again. "
United States
Matthew
The price is €119
includes taxes & fees
30 Mar - 31 Mar
Fairfield Inn & Suites Seneca Clemson Univ Area

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place and location, great mattress, "
United States
Jeffrey
The price is €117
includes taxes & fees
16 Mar - 17 Mar
Lakeside Lodge Clemson

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (731 reviews)
"Very nice and helpful at the fronte desk. Nice room and very comfortable bed"
United States
Crystal
The price is €68
includes taxes & fees
23 Mar - 24 Mar
Days Inn by Wyndham Seneca / Clemson Area

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (66 reviews)
"Excellent stay."
United States
Beonca
The price is €115
includes taxes & fees
18 Mar - 19 Mar
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (652 reviews)
"Room was clean and staff was very efficient. "
United States
Judith
The price is €97
includes taxes & fees
3 Apr - 4 Apr
Best Western Seneca-Clemson

Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (685 reviews)
"Rooms good for the night. No issues with rooms"
United States
Sofia
The price is €120
includes taxes & fees
16 Mar - 17 Mar
Hampton Inn & Suites Seneca-Clemson Area

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (815 reviews)
"The hotel was very clean staff was amazing "
United States
Clifford
The price is €111
includes taxes & fees
31 Mar - 1 Apr
Tru by Hilton Seneca Clemson

Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (903 reviews)
"Staff was great and our beds were very comfortable!"
United States
Laurie
The price is €51
includes taxes & fees
30 Mar - 31 Mar
Quality Inn Clemson near University

Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (412 reviews)
"Clean room Friendly Staff"
United States
Andrina
The price is €50
includes taxes & fees
22 Mar - 23 Mar
Quality Inn & Suites Easley - Greenville

Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (788 reviews)
"Spotless room, comfortable bed, friendly and attentive staff, breakfast was quite nice"
United States
Teresa
The price is €60
includes taxes & fees
20 Mar - 21 Mar
Baymont by Wyndham Easley/Greenville

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very good, (1,001 reviews)
"The lake view was perfect. Room is great and so are the employees!"
United States
Tramaness
The price is €57
includes taxes & fees
8 Apr - 9 Apr
Days Inn by Wyndham Anderson

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.0 out of 10, Wonderful, (600 reviews)
"Hotel is centrally located to a lot of restaurants, shopping and only about 10 minutes from Clemson."
United States
Breane
The price is €100
includes taxes & fees
22 Mar - 23 Mar
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
Anderson
8.2 out of 10, Very good, (1,000 reviews)
"Room was clean, front desk people were very nice. "
United States
Caressa
The price is €74
includes taxes & fees
5 Apr - 6 Apr
Microtel Inn & Suites by Wyndham Anderson/Clemson

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
Anderson
9.0 out of 10, Wonderful, (704 reviews)
"Rooms were clean, staff were friendly, and we had 2 good night’s sleep."
United States
Sadie
The price is €96
includes taxes & fees
26 Mar - 27 Mar
Hilton Garden Inn Anderson

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
Lavonia
9.0 out of 10, Wonderful, (391 reviews)
"Room was clean and staff was very friendly."
United States
clay
The price is €135
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites Lavonia

Woodspring Suites Anderson North I-85

Woodspring Suites Anderson North I-85
2.5 star property
Anderson
7.8 out of 10, Good, (97 reviews)
"Home away from home, great staff"
United States
Selena
The price is €71
includes taxes & fees
26 Mar - 27 Mar
Woodspring Suites Anderson North I-85

Residence Inn by Marriott Anderson Clemson

Residence Inn by Marriott Anderson Clemson
3.0 star property
Anderson
9.6 out of 10, Exceptional, (98 reviews)
"Nice "
United States
Antonio
The price is €138
includes taxes & fees
29 Mar - 30 Mar
Residence Inn by Marriott Anderson Clemson

Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (231 reviews)
"Room was great and the staff polite and helpful "
United States
Sheila D
The price is €139
includes taxes & fees
22 Mar - 23 Mar
Home2 Suites by Hilton Anderson Downtown

Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (362 reviews)
"Clean Good parking"
United States
Jade
The price is €97
includes taxes & fees
21 Mar - 22 Mar
Hampton Inn Hartwell
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Where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most.

Downtown

City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Tru by Hilton Seneca Clemson is ranked highly by Expedia customers. This hotel is a short 15-minute walk from Clemson University, and it offers free breakfast and free parking. Traveller reviews also recommend Lakeside Lodge Clemson and Hampton Inn & Suites Seneca-Clemson Area as top choices for your visit. See all available top hotels, or vacation rentals in Seneca.
What are some of the best holiday rentals that Seneca has to offer?
Quiet cove, deep water, minutes to Clemson, pet friendly, easy path to the dock: This highly rated holiday home rental in Seneca is located on a lake, and has a patio, a private garden and a BBQ to put you at ease in your new surroundings. It has 4 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. Some other homes for rent in Seneca include Lake House with Dock, Pool, and Pet Friendly. 8 Minutes from Clemson. and New to VRBO! Big water views, private dock, pool table, 15 min Clemson!. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Days Inn by Wyndham Seneca / Clemson Area and Tru by Hilton Seneca Clemson. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel located near Clemson University. Features free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Hampton Inn & Suites Seneca-Clemson Area and Days Inn by Wyndham Seneca / Clemson Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 299 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Keowee Reservoir, Lake Keowee and Lake Hartwell. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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