Lake Keowee South Carolina

Seneca Hotels

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Our top choices for Seneca hotels

1. Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
Seneca
9.0 out of 10, Wonderful, (1,013 reviews)
"I enjoyed my stay and all the amenities were excellent! I can’t wait to return!"
United States
Renata
The price is €117
includes taxes & fees
14 Jun - 15 Jun
Lakeside Lodge Clemson

2. Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
Seneca
9.4 out of 10, Exceptional, (235 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
The price is €114
includes taxes & fees
18 Jun - 19 Jun
Fairfield Inn & Suites Seneca Clemson Univ Area

3. Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (712 reviews)
"Clean room comfortable beds"
United States
Cheryl
The price is €86
includes taxes & fees
21 Jun - 22 Jun
Quality Inn Seneca Clemson Area US-123

4. Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
Seneca
6.8 out of 10, (752 reviews)
"Clean and comfortable "
United States
Robyn
The price is €71
includes taxes & fees
18 Jun - 19 Jun
Days Inn by Wyndham Seneca / Clemson Area

5. Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
Seneca
9.2 out of 10, Wonderful, (845 reviews)
"Everything about this hotel was great the staff was very friendly rooms was very clean great location I highly suggest staying here"
United States
Jason
The price is €100
includes taxes & fees
5 Jul - 6 Jul
Tru by Hilton Seneca Clemson

6. Best Western Seneca-Clemson

Best Western Seneca-Clemson
2.5 star property
Seneca
8.4 out of 10, Very good, (663 reviews)
"Friendly staff, comfortable bed"
United States
Michelle
The price is €92
includes taxes & fees
15 Jun - 16 Jun
Best Western Seneca-Clemson

7. Hampton Inn & Suites Seneca-Clemson Area

Hampton Inn & Suites Seneca-Clemson Area
2.5 star property
Seneca
9.2 out of 10, Wonderful, (722 reviews)
"Nice staff, clean rooms, nice breakfast "
United States
Daren
The price is €113
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn & Suites Seneca-Clemson Area

8. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
2.0 star property
Seneca
9.8 out of 10, Exceptional, (78 reviews)
"Awesome place "
United States
Jason
The price is €134
includes taxes & fees
14 Jul - 15 Jul
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

9. Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
Anderson
9.2 out of 10, Wonderful, (624 reviews)
"Room was clean and customer service was excellent, check in was smooth "
United States
Gina
The price is €102
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

10. Hampton Inn Hartwell

Hampton Inn Hartwell
2.5 star property
Hartwell
9.0 out of 10, Wonderful, (373 reviews)
"Nice hotel for the area. "
United States
Judith
The price is €118
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn Hartwell

11. Home2 Suites by Hilton Anderson Downtown

Home2 Suites by Hilton Anderson Downtown
3.0 star property
Anderson
9.4 out of 10, Exceptional, (244 reviews)
"Clean, great location with easy access. Great staff and affordable."
United States
Ronald
The price is €134
includes taxes & fees
5 Jul - 6 Jul
Home2 Suites by Hilton Anderson Downtown

12. Hampton Inn Anderson/ Alliance Business Park

Hampton Inn Anderson/ Alliance Business Park
2.5 star property
Anderson
9.2 out of 10, Wonderful, (849 reviews)
"This place is always clean and staff is so kind and helpful"
United States
Osiry
The price is €109
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn Anderson/ Alliance Business Park

13. Super 8 by Wyndham Anderson/Clemson Area

Super 8 by Wyndham Anderson/Clemson Area
2.5 star property
Anderson
6.6 out of 10, (292 reviews)
"I completely enjoyed my stay"
United States
Mia
The price is €61
includes taxes & fees
14 Jun - 15 Jun
Super 8 by Wyndham Anderson/Clemson Area

14. Baymont by Wyndham Easley/Greenville

Baymont by Wyndham Easley/Greenville
2.5 star property
Easley
7.4 out of 10, Good, (830 reviews)
"I loved my stay. one of my first hotels I've stayed at, and it was a great experience."
United States
Samantha
The price is €74
includes taxes & fees
14 Jun - 15 Jun
Baymont by Wyndham Easley/Greenville

15. Carolina Inn Anderson Clemson Area

Carolina Inn Anderson Clemson Area
2.5 star property
Anderson
8.4 out of 10, Very good, (5 reviews)
"The staff is great "
United States
Luis Fernando
The price is €53
includes taxes & fees
16 Jun - 17 Jun
Carolina Inn Anderson Clemson Area

16. Quality Inn & Suites Easley - Greenville

Quality Inn & Suites Easley - Greenville
2.5 star property
Easley
7.0 out of 10, Good, (464 reviews)
"The manager was great. Room quality for value was also great."
United States
Jennifer
The price is €63
includes taxes & fees
5 Jul - 6 Jul
Quality Inn & Suites Easley - Greenville

17. Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
Anderson
8.0 out of 10, Very good, (1,015 reviews)
"Everything about the place was great"
United States
Eli
The price is €58
includes taxes & fees
24 Jun - 25 Jun
Days Inn by Wyndham Anderson

18. Quality Inn Clemson near University

Quality Inn Clemson near University
2.5 star property
Anderson
7.0 out of 10, Good, (940 reviews)
"Clean room,ac in the middle of a decent size town, overall good hotel"
United States
Roberto
The price is €56
includes taxes & fees
8 Jul - 9 Jul
Quality Inn Clemson near University

19. Holiday Inn Express Anderson by IHG

Holiday Inn Express Anderson by IHG
2.5 star property
Anderson
8.4 out of 10, Very good, (399 reviews)
"The room was clean and comfortable with great AC. The hotel staff was very pleasant and helpful. I would definitely stay there again."
United States
Lawrence Edward
The price is €102
includes taxes & fees
12 Jul - 13 Jul
Holiday Inn Express Anderson by IHG

20. Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
Clemson
8.2 out of 10, Very good, (1,003 reviews)
"We always stay here when in Clemson. It's convenient and the breakfast and restaurant are great."
United States
Greg
The price is €91
includes taxes & fees
15 Jun - 16 Jun
Best Western Plus Clemson Hotel & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Seneca

Find the best Seneca areas for the activities you enjoy most.

Downtown

City centre Seneca captures the essence of small-town Southern charm with its well-preserved railway heritage and historic brick buildings. Tree-lined streets lead to charming shops and local eateries housed in structures dating back to the 1800s. Ram Cat Alley's colourful murals tell stories of local history while the old courthouse square hosts community gatherings. This walkable district offers a peaceful retreat from big city life. Visitors can browse antique stores for railway memorabilia, sample authentic Southern comfort food, or explore the cultural exhibits at the Bertha Lee Strickland Museum. The nearby Lake Keowee provides outdoor recreation just minutes away.

Serenity Bay

Serenity Bay offers a peaceful retreat within Saxony Forest's coastal embrace. The quiet residential streets wind through mature trees, creating a tranquil atmosphere away from tourist crowds. Nature lovers can explore nearby Lake Keowee or enjoy the neighborhood's forest trails. The area perfectly balances woodland serenity with beach proximity. Visitors should plan for self-contained holiday rentals rather than hotels. While dining options are limited within the area, the natural surroundings provide ideal conditions for relaxation and outdoor recreation.

Pine Ridge Point

Lake Keowee's serene waters lap against the shores of Pine Ridge Point, a tranquil residential haven in Seneca. Private docks stretch into crystal-clear waters where boats gently bob. Towering pines create natural privacy between lakefront homes. Visitors enjoy peaceful mornings watching mist rise over the water. This area offers an authentic lakeside living experience without tourist crowds. Holiday rentals range from cosy cabins to luxury estates with private boat slips. Days revolve around swimming, fishing, and water sports on Lake Keowee. Nature trails wind through mature forests for hiking and birdwatching.

Indian Oaks

Indian Oaks offers a tranquil retreat in suburban Seneca where mature oak trees create natural canopies over peaceful residential streets. This family-oriented community provides an authentic glimpse into American suburban living without tourist crowds. Landscaped yards and community green spaces showcase South Carolina's native beauty. Visitors can enjoy quiet morning walks on spacious pavements while listening to birdsong. Lake Keowee lies just beyond the area boundaries for those seeking water activities. With minimal commercial presence, Indian Oaks delivers a genuinely restful experience away from urban bustle.

Stay near popular Seneca attractions

Learn more about Seneca

Nestled along Lake Keowee's shoreline, this charming town offers spectacular waterfront activities from kayaking to fishing at South Cove County Park. Nearby Stumphouse Tunnel and Issaqueena Falls provide fascinating historical exploration and refreshing natural beauty, especially during summer's humid afternoons.

Lake Keowee South Carolina

Top Seneca Hotel Reviews

More cheap stays in Seneca

Frequently asked questions

Where is the best place for a stay in Seneca?
Lakeside Lodge Clemson is one of the top choices for your stay based on our traveller data. This hotel is a short 7-minute walk from Lake Hartwell, and it offers a restaurant and free parking. Other good options for your visit include Quality Inn Seneca Clemson Area US-123 and Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy. See all available top hotels, or vacation rentals in Seneca.
What are some of the best holiday rentals that Seneca has to offer?
Lake House Near Clemson Private Boat Dock WiFi 65" TV Grill Kayaks Deep Water: This highly rated holiday home rental in Seneca is located on a lake, and has a fireplace, a patio and a BBQ to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. You can relax into your holiday with a garden and a selection of games. Some other homes for rent in Seneca include 4/3, Waterfront Home w/ Covered Dock, Child Sand Play Pit, Pet Friendly! and Waterfront 3br home on Lake Hartwell near Clemson. See all vacation rentals in Seneca.
If I need to cancel my hotel reservation in Seneca, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable if cancelled before the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Seneca.
What's the best family accommodation in Seneca?
Fairfield Inn & Suites Seneca Clemson Univ Area is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Also, attractions in the area such as Ultimate Action Sports are fun for the whole family. Find more child-friendly accommodations in Seneca.
What is the top LGBTQ-friendly accommodation in Seneca?
Hampton Inn & Suites Seneca-Clemson Area is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Tru by Hilton Seneca Clemson is another good choice for your trip. See all available hotels listed as LGBTQ-friendly in Seneca.
What's the best dog-friendly hotel in Seneca?
Lakeside Lodge Clemson is a top hotel for people travelling with their pets, and offers a restaurant and a seasonal outdoor pool for its human guests. Other good choices for you and your pet's trip include Tru by Hilton Seneca Clemson and Quality Inn Seneca Clemson Area US-123. See more pet-friendly hotel accommodations in Seneca.
What are some hotels with pools in Seneca?
Lakeside Lodge Clemson: Hotel, 7-minute walk from Lake Hartwell. Features free self parking, a seasonal outdoor pool and complimentary wireless Internet access. Quality Inn Seneca Clemson Area US-123 and Fairfield Inn & Suites Seneca Clemson Univ Area are two additional hotels that feature an on-site pool. View all hotels with pools in Seneca.
What is staying in Seneca like?
Visitors to Seneca will definitely enjoy the sporting events, lakeside setting and university setting. Welcoming and scenic, this city also attracts tourists with its cafes. In Seneca, there are 305 hotels and other accommodation options to choose from. Find out more about Seneca.
What should I see while I'm in Seneca?
Cultural venues include The Gauntlet and Oconee Community Theatre. Natural beauty is on display at Lake Keowee, Lake Hartwell and Keowee Reservoir. Exploring the waterfront is a great activity, and Keowee Key Golf Course is one place to visit. Take a look at what more there is to see and do in Expedia's Seneca guide.
What's the seasonal weather in Seneca?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 8°C. Average annual precipitation for Seneca is 1565 mm.

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