Santa Ana Hotel Guide. Hotels in Downtown Santa Ana, Santa Ana, United States of America

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Our top choices for Downtown Santa Ana hotels

Ayres Hotel Seal Beach - Cypress

Ayres Hotel Seal Beach - Cypress
3.0 star property
19.1 km from Downtown Santa Ana
9.4 out of 10, Exceptional, (1292)
"Always a great place to stay"
United States
Pao
The price is €148
includes taxes & fees
18 Dec - 19 Dec
Ayres Hotel Seal Beach - Cypress

Ocean Surf Inn & Suites

Ocean Surf Inn & Suites
2.0 star property
19.3 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (1010)
"We will definitely stay again! Nice rooms, friendly staff and great location."
United States
Patricia
The price is €119
includes taxes & fees
29 Dec - 30 Dec
Ocean Surf Inn & Suites

The Queen Mary

The Queen Mary
3.0 star property
29.8 km from Downtown Santa Ana
8.8 out of 10, Excellent, (3798)
"Everything about my stay at the Queen Mary was excellent! "
United States
Brian
The price is €120
includes taxes & fees
17 Dec - 18 Dec
The Queen Mary

Hyatt Regency Long Beach

Hyatt Regency Long Beach
4.0 star property
29.9 km from Downtown Santa Ana
9.2 out of 10, Wonderful, (1707)
"Very nice hotel"
United States
Ytaliene Francheska
The price is €197
includes taxes & fees
16 Dec - 17 Dec
Hyatt Regency Long Beach

Best Western Plus Newport Mesa Inn

Best Western Plus Newport Mesa Inn
3.0 star property
9.6 km from Downtown Santa Ana
8.8 out of 10, Excellent, (1005)
"Great free breakfast and super quiet. Right near freeway entrance for easy access to basically anywhere you want to go "
United States
Kathryn
The price is €116
includes taxes & fees
4 Jan - 5 Jan 2026
Best Western Plus Newport Mesa Inn

Staybridge Suites Long Beach Airport by IHG

Staybridge Suites Long Beach Airport by IHG
3.0 star property
26 km from Downtown Santa Ana
8.8 out of 10, Excellent, (797)
"clean, excellent staff, great breakfast, and great evening snack."
United States
Pamela
The price is €195
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Long Beach Airport by IHG

Hotel Huntington Beach

Hotel Huntington Beach
3.0 star property
11.8 km from Downtown Santa Ana
8.0 out of 10, Very good, (2848)
"Great stay! "
United States
Genevieve
Hotel Huntington Beach

OC Hotel Costa Mesa

OC Hotel Costa Mesa
2.5 star property
10.4 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (1483)
"Excellent hotel "
United States
Frederic
OC Hotel Costa Mesa

Lumea by the Sea

Lumea by the Sea
3.0 star property
29.2 km from Downtown Santa Ana
9.6 out of 10, Exceptional, (987)
"Great place to stay"
United States
Jessica
Lumea by the Sea

Good Nite Inn Buena Park

Good Nite Inn Buena Park
2.0 star property
18 km from Downtown Santa Ana
8.8 out of 10, Excellent, (2521)
"Always great stay here"
United States
Reginald
The price is €73
includes taxes & fees
16 Dec - 17 Dec
Good Nite Inn Buena Park

Ayres Hotel & Spa Mission Viejo – Lake Forest

Ayres Hotel & Spa Mission Viejo – Lake Forest
3.5 star property
24.7 km from Downtown Santa Ana
9.2 out of 10, Wonderful, (1013)
"Everything was very clean, staff is always nice, especially the front desk."
United States
kathleen
The price is €110
includes taxes & fees
16 Dec - 17 Dec
Ayres Hotel & Spa Mission Viejo – Lake Forest

Days Inn & Suites by Wyndham Fullerton

Days Inn & Suites by Wyndham Fullerton
2.0 star property
19.6 km from Downtown Santa Ana
8.8 out of 10, Excellent, (1626)
"Nice room, good breakfast."
United States
Yvonne
The price is €83
includes taxes & fees
4 Jan - 5 Jan 2026
Days Inn & Suites by Wyndham Fullerton

Hotel Royal

Hotel Royal
2.5 star property
29.5 km from Downtown Santa Ana
8.4 out of 10, Very good, (1007)
"Staff is so friendly and helpful and we will ALWAYS stay here when we visit Long Beach!"
United States
Heidi
The price is €79
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel Royal

Costa Mesa Marriott

Costa Mesa Marriott
4.0 star property
6.4 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (1381)
"Room was clean & breakfast was good."
United States
Sally
The price is €116
includes taxes & fees
24 Dec - 25 Dec
Costa Mesa Marriott

DoubleTree by Hilton Buena Park

DoubleTree by Hilton Buena Park
4.0 star property
17 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (1245)
"Great stay"
United States
norma
The price is €111
includes taxes & fees
4 Jan - 5 Jan 2026
DoubleTree by Hilton Buena Park

Holiday Inn Diamond Bar - Pomona by IHG

Holiday Inn Diamond Bar - Pomona by IHG
3.0 star property
28.3 km from Downtown Santa Ana
8.8 out of 10, Excellent, (1009)
"Great place to stay."
United States
Lilia
The price is €118
includes taxes & fees
3 Jan - 4 Jan 2026
Holiday Inn Diamond Bar - Pomona by IHG

Best Western Plus Irvine Spectrum Hotel

Best Western Plus Irvine Spectrum Hotel
2.5 star property
19.6 km from Downtown Santa Ana
8.4 out of 10, Very good, (1007)
"Was clean, love we had a small living room. Pool area was great and staff was friendly and helpful!"
United States
Alejandra
The price is €96
includes taxes & fees
18 Dec - 19 Dec
Best Western Plus Irvine Spectrum Hotel

Beach Inn Motel

Beach Inn Motel
2.0 star property
29 km from Downtown Santa Ana
8.6 out of 10, Excellent, (379)
"Room was great. For the price and location, I was pleasantly surprised by the space and quality "
United States
Christopher
The price is €96
includes taxes & fees
16 Dec - 17 Dec
Beach Inn Motel

Hotel Mai Downtown Long Beach

Hotel Mai Downtown Long Beach
3.0 star property
29.7 km from Downtown Santa Ana
9.2 out of 10, Wonderful, (772)
"Easy booking, clean room, excellent staff. "
United States
Eddie
Hotel Mai Downtown Long Beach

ALO Hotel by Ayres, Orange

ALO Hotel by Ayres, Orange
3.5 star property
5.1 km from Downtown Santa Ana
9.0 out of 10, Wonderful, (2388)
"Rooms were great and the staff was very nice!"
United States
Lannatt
The price is €95
includes taxes & fees
4 Jan - 5 Jan 2026
ALO Hotel by Ayres, Orange
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Downtown Santa Ana

Find the best Downtown Santa Ana areas for the activities you enjoy most.

North Tustin

While North Tustin isn't home to many top sights, The Market Place and Santa Ana Zoo are some notable places to visit nearby.

Riverview West

While Riverview West may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Disney California Adventure® Park and Disneyland® Resort.

Lyon Street

While Lyon Street isn't home to many top sights, Santa Ana Zoo and Old Orange County Courthouse are some notable places to visit nearby.

Park Santiago

While visiting Park Santiago, you might make a stop by sights like Discovery Science Center and Santiago Park.

Riverview

While Riverview may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bowers Museum and The Outlets at Orange.

Top Downtown Santa Ana Hotel Reviews

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Frequently asked questions

What is Downtown Santa Ana like?
Guests are sure to enjoy their time checking out all that Santa Ana's Downtown Santa Ana neighbourhood has to offer. Consider a visit to Santora Arts Building as part of your Downtown Santa Ana travel plans.
How many hotels will I be able to find in the Downtown Santa Ana area?
Expedia has 7 Downtown Santa Ana hotels and other accommodation options, and one might make a good home base for venturing out into the greater Santa Ana area.
If I need to cancel my hotel reservation in Downtown Santa Ana, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the "fully refundable" filter to view the best options available in Downtown Santa Ana.
What are the top things to see and do in Downtown Santa Ana?
Santora Arts Building is an attraction you might want to check out while you're in Downtown Santa Ana. Old Orange County Courthouse and Dr. Willella Howe-Waffle House and Medical Museum are also worth a visit when you're out sightseeing in Santa Ana.