Seneca Hotel Guide. Hotels in Downtown, Seneca, United States of America

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This weekend
5 Jun - 7 Jun
Next weekend
12 Jun - 14 Jun

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Our top choices for Downtown hotels

Free daily on-the-go breakfast

Quality Inn Seneca Clemson Area US-123

Quality Inn Seneca Clemson Area US-123
2.5 star property
Downtown
8.0 out of 10, Very good, (708 reviews)
"Clean room comfortable beds"
United States
Cheryl
Quality Inn Seneca Clemson Area US-123
Property amenity

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG

Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
2.5 star property
25 km from Downtown
9.2 out of 10, Wonderful, (622 reviews)
"Room was clean and customer service was excellent, check in was smooth "
United States
Gina
Holiday Inn Express Hotel & Suites Anderson-I-85 by IHG
Property amenity

Fairfield Inn & Suites Seneca Clemson Univ Area

Fairfield Inn & Suites Seneca Clemson Univ Area
3.0 star property
2 km from Downtown
9.4 out of 10, Exceptional, (234 reviews)
"Excellent in every way … staff, room, amenities and very comfortable bed!"
United States
Sarah
Fairfield Inn & Suites Seneca Clemson Univ Area
Hallway

The Inn at Patrick Square

The Inn at Patrick Square
3.5 star property
15.2 km from Downtown
9.8 out of 10, Exceptional, (856 reviews)
"Terrific place to stay and the staff was very helpful too."
United States
Anne
The Inn at Patrick Square
Free breakfast

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center
2.5 star property
11.8 km from Downtown
8.2 out of 10, Very good, (1,008 reviews)
"We always stay here when in Clemson. It's convenient and the breakfast and restaurant are great."
United States
Greg
Best Western Plus Clemson Hotel & Conference Center
Free daily on-the-go breakfast

Days Inn by Wyndham Seneca / Clemson Area

Days Inn by Wyndham Seneca / Clemson Area
2.0 star property
3.1 km from Downtown
6.8 out of 10, (752 reviews)
"Clean and comfortable "
United States
Robyn
Days Inn by Wyndham Seneca / Clemson Area
Hallway

Hampton Inn & Suites Lavonia

Hampton Inn & Suites Lavonia
2.5 star property
30.7 km from Downtown
9.0 out of 10, Wonderful, (407 reviews)
"The breakfast was great, the staff was very friendly and the hotel very clean. We highly recommend."
United States
Russell
Hampton Inn & Suites Lavonia
Lobby

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
4.0 star property
10.6 km from Downtown
9.8 out of 10, Exceptional, (806 reviews)
"Great location great restaurant"
United States
Jennifer
The Shepherd Hotel Downtown Clemson
Lobby

Microtel Inn & Suites by Wyndham Anderson/Clemson

Microtel Inn & Suites by Wyndham Anderson/Clemson
2.0 star property
24.8 km from Downtown
8.4 out of 10, Very good, (1,003 reviews)
"Wonderful staff very helpful"
United States
atlantis
Microtel Inn & Suites by Wyndham Anderson/Clemson
Lobby lounge

The Abernathy of Clemson

The Abernathy of Clemson
4.0 star property
10.1 km from Downtown
9.6 out of 10, Exceptional, (602 reviews)
"Easy parking, great location. Will stay there again"
United States
William
The Abernathy of Clemson
Golf

Clemson University's James F. Martin Inn

Clemson University's James F. Martin Inn
3.0 star property
10.3 km from Downtown
9.4 out of 10, Exceptional, (1,000 reviews)
"Lovely place to stay right on the lake. "
United States
Sara
Clemson University's James F. Martin Inn
Desk, soundproofing, iron/ironing board, free WiFi

Budget Inn Express

Budget Inn Express
2.0 star property
19.9 km from Downtown
5.8 out of 10, (252 reviews)
"Facilities and entertainment surround the Hotel in short trips!"
United States
Stephen
Budget Inn Express
Lobby

Hilton Garden Inn Anderson

Hilton Garden Inn Anderson
3.0 star property
25.7 km from Downtown
9.0 out of 10, Wonderful, (728 reviews)
"Had a nice stay bed was comfortable and room was clean."
United States
Jon
Hilton Garden Inn Anderson
Suite, 1 King Bed with Sofa bed, Non Smoking (Efficiency) | Bathroom

Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area
2.5 star property
11.7 km from Downtown
8.4 out of 10, Very good, (1,004 reviews)
"Great breakfast and friendly staff made our stay enjoyable."
United States
Lon
Comfort Inn & Suites Clemson - University Area
Aerial view

Lakeside Lodge Clemson

Lakeside Lodge Clemson
2.5 star property
8.6 km from Downtown
9.0 out of 10, Wonderful, (1,003 reviews)
"Beautiful property and nice room."
United States
Lynzee
Lakeside Lodge Clemson
Studio Suite, 1 King Bed, Non Smoking | Jetted bathtub

Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson
2.0 star property
25.6 km from Downtown
8.0 out of 10, Very good, (1,004 reviews)
"Everything about the place was great"
United States
Eli
Days Inn by Wyndham Anderson
Snack bar

Hampton Inn Anderson

Hampton Inn Anderson
2.5 star property
25 km from Downtown
8.8 out of 10, Excellent, (416 reviews)
"Convenient location and friendly front desk staff"
United States
Mark
Hampton Inn Anderson
Terrace/patio

Tru by Hilton Seneca Clemson

Tru by Hilton Seneca Clemson
2.5 star property
8.4 km from Downtown
9.2 out of 10, Wonderful, (845 reviews)
"Everything about this hotel was great the staff was very friendly rooms was very clean great location I highly suggest staying here"
United States
Jason
Tru by Hilton Seneca Clemson
Indoor pool

Holiday Inn Express Hotel & Suites Lavonia by IHG

Holiday Inn Express Hotel & Suites Lavonia by IHG
2.5 star property
30.7 km from Downtown
8.8 out of 10, Excellent, (420 reviews)
"Great place ro stay"
United States
Ida
Holiday Inn Express Hotel & Suites Lavonia by IHG
Business centre

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson
2.5 star property
25 km from Downtown
7.0 out of 10, Good, (887 reviews)
"It was peaceful with lots of food options around. Room was clean and the beds were comfortable."
United States
Emely
Baymont by Wyndham Anderson Clemson
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Downtown

Find the best Downtown areas for the activities you enjoy most.

Serenity Bay

When in Serenity Bay, you can plan a visit to Keowee Key Golf Course and Lake Keowee, some noteworthy sights in the nearby area.

Female Kayaker on Lake Keowee at Sunset

Pine Ridge Point

If you're looking for some top things to see and do in Pine Ridge Point and surrounding area, you can visit Lake Keowee and World of Energy.

Indian Oaks

While Indian Oaks may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like The Gauntlet and Seneca Historic District.

Keowee Plantation

While Keowee Plantation isn't home to many top sights, The Gauntlet and Seneca Historic District are some notable places to visit nearby.

Top Downtown Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

10/10 Excellent
"S tier breakfast"
Rueben 1-night trip
Posted 9 hours ago
Best Western Plus Clemson Hotel & Conference Center

Frequently asked questions

What is Downtown like?
Travellers to the Downtown neighbourhood in Seneca will be sure to enjoy their stay. Make sure that you visit Seneca Historic District and The Gauntlet as part of your Downtown travel plans.
Where is the best place to stay in Downtown?
Based on our traveller data, Quality Inn Seneca Clemson Area US-123 is one of the top choices for your stay in Downtown. This hotel offers free breakfast and free parking.
How many hotels will I be able to find in Downtown?
If you're searching for places to stay in Seneca, choose from one of Expedia's 13 hotels and other accommodation options in Downtown.
If I need to cancel my hotel reservation in Downtown, will I receive a refund?
Yes! You'll find that most room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to review the best deals in Downtown.
What can I see and do in this Seneca neighbourhood?
Seneca Historic District, The Gauntlet and Blue Ridge Arts Center are just a few attractions to check out in Downtown. As you're discovering the neighbourhood, Bertha Lee Strickland Cultural Museum and Oconee County Library Seneca Branch are some other places worth a visit. Seneca City Hall, Golden Corner Plaza and Oconee Community Theatre are just a few of the places to visit in and around Downtown. While you're out sightseeing in Seneca, make sure that you visit other sights such as Applewood Shopping Center or Wyndham Plaza.