Cheap Flights to Cayos Zapatilla: Cayos Zapatilla Flight Deals

View €276 flight on Wed, 3 Jun 2026Opens in a new window

Popular airlines

  • American Airlines

  • Avianca

  • United

  • Delta

  • Copa

  • Aeromexico

  • KLM

  • Be in the know

    Get alerts if flight prices drop or rise*

  • Book smarter

    Save up to 15% on select hotels after you book a flight*

  • Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap round-trip flights to Cayos Zapatilla

Prices were available within the past 7 days and start at €276 for one-way flights and €582 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Copa
Thu, 21 May - Thu, 28 May
JFK
New York
PTY
Panama City
€582 Return, found 6 days ago
€582
Return
found 6 days ago
Select Copa flight, departing Thu, 21 May from New York to Panama City, returning Thu, 28 May, priced at €582 found 6 days ago
avianca
Fri, 22 May - Tue, 26 May
JFK
New York
PTY
Panama City
€612 Return, found 4 days ago
€612
Return
found 4 days ago
Select avianca flight, departing Fri, 22 May from New York to Panama City, returning Tue, 26 May, priced at €612 found 4 days ago
Turkish Airlines
Wed, 13 May - Wed, 27 May
MXP
Milan
PTY
Panama City
€655 Return, found 13 hours ago
€655
Return
found 13 hours ago
Select Turkish Airlines flight, departing Wed, 13 May from Milan to Panama City, returning Wed, 27 May, priced at €655 found 13 hours ago
Air Europa
Mon, 1 Feb - Mon, 8 Feb
MXP
Milan
PTY
Panama City
€668 Return, found 16 hours ago
€668
Return
found 16 hours ago
Select Air Europa flight, departing Mon, 1 Feb from Milan to Panama City, returning Mon, 8 Feb, priced at €668 found 16 hours ago
Iberia
Wed, 20 Jan - Wed, 10 Mar
MAD
Madrid
PTY
Panama City
€682 Return, found 3 days ago
€682
Return
found 3 days ago
Select Iberia flight, departing Wed, 20 Jan from Madrid to Panama City, returning Wed, 10 Mar, priced at €682 found 3 days ago

Frequently asked questions

How do I find cheap flights to Cayos Zapatilla that have flexible change policies?
By using our smart "No change fee" filter, that's how. Just enter your dates and other details, click the "Search" button, then tick the checkbox directly underneath the "Flexible change policies" heading (it's on the left). Expedia makes it a snap to find flexible and affordable airfares to Cayos Zapatilla.
Which airlines fly to Cayos Zapatilla?
When you're ready to book your ticket to or near Cayos Zapatilla, these top carriers look forward to welcoming you on board:

  • Copa Airlines - 772 flights to or near Cayos Zapatilla each month, including 772 flights to Tocumen Intl. Airport (PTY) per month.
  • United Airlines - 91 flights to or near Cayos Zapatilla each month, including 91 flights to Tocumen Intl. Airport (PTY) per month.
  • American Airlines - 60 flights to or near Cayos Zapatilla each month, including 60 flights to Tocumen Intl. Airport (PTY) per month.

How can I find cheap tickets to Cayos Zapatilla?
To pick up an awesome deal to Cayos Zapatilla, book well in advance. Also make use of Expedia's "flexible dates" feature at the top of your search results. This will list the cheapest prices for nearby days. In the last seven days, €582 was the lowest price for a flight to Cayos Zapatilla.
How much is a flight to Cayos Zapatilla?
There were a lot of inexpensive fares for the taking in the last seven days, with the cost of a round-trip flight to Cayos Zapatilla ranging between €582 and €691. Many lucky holiday makers purchased one-way flights from New York (JFK) for just €276.
What are the most popular airports to fly into in Cayos Zapatilla?
The main gateway to Cayos Zapatilla, about 963 flights land at Tocumen Intl. Airport (PTY) each month. Track down the best deal, book your seat and get ready to discover this amazing region.
How much is a plane ticket to Cayos Zapatilla?
In the last seven days, plane tickets to Cayos Zapatilla varied from €582 to €691.
What months are the cheapest to book a flight to Cayos Zapatilla?
To grab cheap flights to Cayos Zapatilla, book during February when prices are at their lowest. When's the most costly? In the U.S, it's the festive month of December.

Travel information

Destination airport
Tocumen Intl.
Destination airport IATA code
PTY
Destination city name
Panama City
Return price
€582

Trending flights to Cayos Zapatilla

Prices were available within the past 7 days and start at €276 for one-way flights and €582 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

British Airways
Mon, 9 Nov - Mon, 23 Nov
DUB
Dublin
PTY
Panama City
€691 Return, found 5 days ago
€691
Return
found 5 days ago
Select British Airways flight, departing Mon, 9 Nov from Dublin to Panama City, returning Mon, 23 Nov, priced at €691 found 5 days ago
*Available to Expedia members.