Cheap Flights to Santa Cruz: Santa Cruz Flight Deals

View €62 flight on Wed, 12 Nov 2025Opens in a new window

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Cheap round-trip flights to Santa Cruz

Prices were available within the past 7 days and start at €62 for one-way flights and €123 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

LATAM Airlines Group
Thu, 8 Jan - Thu, 15 Jan
BOG
Bogotá
MDE
Medellin
€123 Return, found 5 hours ago
€123
Return
found 5 hours ago
Select LATAM Airlines Group flight, departing Thu, 8 Jan from Bogotá to Medellin, returning Thu, 15 Jan, priced at €123 found 5 hours ago
JetBlue Airways
Mon, 27 Oct - Wed, 5 Nov
JFK
New York
MDE
Medellin
€302 Return, found 3 days ago
€302
Return
found 3 days ago
Select JetBlue Airways flight, departing Mon, 27 Oct from New York to Medellin, returning Wed, 5 Nov, priced at €302 found 3 days ago
APG Distribution System
Mon, 10 Nov - Tue, 9 Dec
BOG
Bogotá
EOH
Medellin
€322 Return, found 3 days ago
€322
Return
found 3 days ago
Select APG Distribution System flight, departing Mon, 10 Nov from Bogotá to Medellin, returning Tue, 9 Dec, priced at €322 found 3 days ago
TAP Portugal
Wed, 25 Feb - Wed, 11 Mar
LIS
Lisbon
MDE
Medellin
€509 Return, found 2 days ago
€509
Return
found 2 days ago
Select TAP Portugal flight, departing Wed, 25 Feb from Lisbon to Medellin, returning Wed, 11 Mar, priced at €509 found 2 days ago
avianca
Sun, 21 Dec - Sat, 3 Jan
MGA
Managua
MDE
Medellin
€546 Return, found 23 hours ago
€546
Return
found 23 hours ago
Select avianca flight, departing Sun, 21 Dec from Managua to Medellin, returning Sat, 3 Jan, priced at €546 found 23 hours ago

Find the cheapest month to fly from Columbus (CMH) to Medellín (MDE)

September is typically the cheapest month to fly

From €219 - €554 per traveller.

Frequently asked questions

What is the name of Santa Cruz's airport?
Santa Cruz has just one airport, Enrique Olaya Herrera Airport (EOH).
How far is Enrique Olaya Herrera Airport (EOH) from central Santa Cruz?
Enrique Olaya Herrera Airport (EOH) is just a short drive from all the action of downtown Santa Cruz. It's located 10 kilometres from the city centre.
What airport is best to fly into Santa Cruz?
Travellers from all around the world pass through Enrique Olaya Herrera Airport (EOH) every day. Hop off the plane, collect your luggage and you'll be 10 kilometres from the central Santa Cruz streets.
How many airlines fly to Santa Cruz?
With 2 air carriers flying to Santa Cruz from at least 13 airports across the world, your perfect flight is just a few clicks away.
Which airlines fly to Santa Cruz?
SATENA and EasyFly are some of the most popular airlines that offer flights to Santa Cruz. Most travellers use Bogotá as a starting point with SATENA flying this route the most.
How many nonstop flights are there to Santa Cruz?
With 268 direct flights running every week, you'll be landing in Santa Cruz before you have time to say, "Are we there yet?"
Where are the most popular flights to Santa Cruz departing from?
Flights to Santa Cruz departing from Bogotá, Monterían and Pereira airports are always popular.
How long is the flight to Santa Cruz Airport?
If you're going to Santa Cruz from Bogotá, you're looking at a flight duration of 1 hour and 8 minutes. Those jetting off from Montería can expect to be on the plane for 1 hour. From Pereira it's roughly 45 minutes away.
How to book the cheapest flight to Santa Cruz?
Don't leave booking your flight to Santa Cruz until the last moment. That's one move frequent jet-setters use to get the best prices. Booking ahead means more options and less expensive flights. Don't stop there, though. Do some research and see if there are multiple airports at your destination. Fares often differ depending on which airport you use. Don't forget to compare fares across airlines too. And finally, remember that it's first in, best dressed. Familiarise yourself with airfare costs and have your credit card ready to snap up a ticket as soon as you see a great bargain. The best deals don't last long.
Do you have any tips for my flight to Santa Cruz?
Wherever you're jetting in from, flying can be a seamless experience if you're prepared. Follow these top travel tips that will help get your Santa Cruz escape started on the right foot. What to pack in your hand luggage:

  • First of all, put in your passport, travel documents, cash and daily medications. Next, you'll want some entertainment to help pass the time. A thrilling novel and a phone crammed with your favourite shows are always good options. If you hope to catch up on some sleep, a neck pillow and a pair of noise-cancelling headphones will also come in handy. Finally, make room for a toothbrush and some deodorant so you'll arrive looking and feeling fresh.

Do not pack the following items in your hand luggage:

  • Check carefully that you don't have sharp objects (like a pocket knife) hiding in your hand luggage. Other prohibited items include explosive or flammable goods, such as aerosol cans and fuel, and liquids and gels in containers with a capacity of more than 3.4 ounces (100 millilitres).

What to wear on a flight:

  • You'll want to go for comfort over style. Prepare for temperature changes by dressing in layers, and wear closed-toe, flat footwear like slip-ons.
  • Deep vein thrombosis (DVT), a blood clot condition caused by extended periods of inactivity, can be a risk on long-haul flights. Make a point of walking around the cabin or do some gentle exercises in your seat to improve your circulation.

How to get through airport security fast when flying to Santa Cruz?
A little pre-planning before your flight will make your trip to Santa Cruz easy and painless. Below are some useful tips for a stress-free journey through security:

  • Security personnel first need to know that you have a valid ID and travel documents before anything else. Have them within easy reach, ready for inspection.
  • After that, both you and your carry-on bag will be X-rayed. To make the process quick and painless, take off anything that is likely to trigger the alarm. Personal belongings like your jacket, belt and earphones will be required to go through the machine.
  • All your electronic devices, including your laptop and phone, are also required to be scanned separately.
  • Remove all gels and liquids from your carry-on luggage. They usually need to be sent through the X-ray scanner separately. Each item should be in a container no larger than 3.4 ounces (100 millilitres) and everything must fit inside a quart-size (one litre), clear zip-close bag.
  • It's also possible you'll be asked to remove your shoes for scanning, so wearing lightweight sneakers is always a smart idea.
  • Take all prohibited items out of your carry-on bag. If you have any sharp objects like a pocket knife or tools, put them in your checked baggage. They won't be allowed on board and will be confiscated.

Book with confidence

Book with confidence

Expedia.ie is an online travel company that specialises in securing the best prices for flights to Santa Cruz. With Expedia you get highly specialised services, combining the best of technology, in-depth knowledge and the best connections in order to offer great deals to Santa Cruz. Expedia shares your passion for travel and has built the best online travel service that promotes and encourages travel. Whether you are looking for cheap flights to Santa Cruz, or are just on the lookout for the best flights to Santa Cruz, you are sure to find the best deals with Expedia.ie.

"One of the many benefits of booking your flights through Expedia is that we are one of the world’s largest online travel agency, which means we use our collective experience and work tirelessly to bring you the best prices. With Expedia you get a user-friendly internet experience and a dedicated customer support service that ensures that everything goes smoothly. The goal of Expedia is to offer premium services at the lowest price, all at one single place. If you wish to save even more try combing a hotel in Santa Cruz to your flight and create a personalised low cost city break or holiday to your favourite destination. Book early and you could save even more!

If you have an Expedia.ie itinerary number and have a question or concern about your travel plans you can call us on (01) 524 5005 from 8am - 10pm Monday to Friday, and 9am - 10pm at weekends and an Expedia agent will help you.

Travel information

Travel information

Destination airport
José María Córdova Intl.
Destination airport IATA code
MDE
Destination city name
Medellín
Return price
€122

Trending flights to Santa Cruz

Prices were available within the past 7 days and start at €62 for one-way flights and €123 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

KLM
Sun, 8 Feb - Mon, 16 Feb
DUB
Dublin
MDE
Medellin
€806 Return, just found
€806
Return
just found
Select KLM flight, departing Sun, 8 Feb from Dublin to Medellin, returning Mon, 16 Feb, priced at €806 just found

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