Santa Cruz Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
26 Feb - 27 Feb
Tomorrow
27 Feb - 28 Feb
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santa Cruz hotels

Reception

Hotel Bossanova

Hotel Bossanova
3.0 star property
Rionegro
9.6 out of 10, Exceptional, (8 reviews)
"Great staff. Location. "
United States
Pedro
The price is €27
10 Mar - 11 Mar
Hotel Bossanova
Reception

Hotel Once22

Hotel Once22
3.0 star property
Sabaneta
9.6 out of 10, Exceptional, (52 reviews)
"Great stay as usual, wonderful service from check-in to check-out"
United States
Al
The price is €40
27 Feb - 28 Feb
Hotel Once22
Terrace/patio

Fairfield by Marriott Medellin Sabaneta

Fairfield by Marriott Medellin Sabaneta
3.5 star property
Sabaneta
9.4 out of 10, Exceptional, (254 reviews)
"The hotel is operated very well and staff is very polite and professional, great food at the restaurant."
Canada
Clayton
The price is €65
7 Mar - 8 Mar
Fairfield by Marriott Medellin Sabaneta
Elite Room, Patio | Terrace/patio

Hotel Ryo 74B Suites by Growing Group

Hotel Ryo 74B Suites by Growing Group
3.0 star property
Laureles
9.6 out of 10, Exceptional, (14 reviews)
"Clean rooms and friendly staff. Would stay there again"
United States
Iris
The price is €37
25 Mar - 26 Mar
Hotel Ryo 74B Suites by Growing Group
Lobby sitting area

Arame Hotel

Arame Hotel
3.0 star property
Envigado
9.2 out of 10, Wonderful, (192 reviews)
"Great staff, clean rooms, helpful service, and very good breakfast"
United States
August
The price is €60
8 Mar - 9 Mar
Arame Hotel
Exterior

La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego
8.8 out of 10, Excellent, (1,001 reviews)
"Best hotel"
United States
Wilfred
The price is €66
5 Mar - 6 Mar
La Quinta by Wyndham Medellin
Building design

Hotel Nutibara

Hotel Nutibara
3.0 star property
La Candelaria
7.2 out of 10, Good, (549 reviews)
"Everything was extremely perfect room was nice! Staff was friendly and helpful "
United States
Matthew
Hotel Nutibara
Terrace/patio

Landmark Hotel

Landmark Hotel
4.0 star property
El Poblado
9.6 out of 10, Exceptional, (280 reviews)
"Amazing stay!"
United States
Ariadny
The price is €103
29 Mar - 30 Mar
Landmark Hotel
Daily buffet breakfast (COP 45000 per person)

ibis Medellin

ibis Medellin
3.0 star property
El Poblado
8.8 out of 10, Excellent, (1,000 reviews)
"My second time in this hotel and love the fact that is centrally located. Will definitely recommend it. "
United States
Enrique
The price is €54
13 Mar - 14 Mar
ibis Medellin
Outdoor spa tub

Hotel Alcaravan Medellín

Hotel Alcaravan Medellín
3.0 star property
Itagüí
7.8 out of 10, Good, (269 reviews)
"Staff was very helpful and caring "
United States
Gloria
Hotel Alcaravan Medellín
Snack bar

The Host Medellin Only Adults

The Host Medellin Only Adults
3.0 star property
El Poblado
9.6 out of 10, Exceptional, (37 reviews)
"Great ambience and room, excellent breakfast "
United States
Shailendra
The price is €133
16 Mar - 17 Mar
The Host Medellin Only Adults
Luxury Suite | Private spa tub

Hotel Attic 33

Hotel Attic 33
3.0 star property
Laureles
9.2 out of 10, Wonderful, (43 reviews)
"Clean room, staff, love the place."
United States
Luis
The price is €50
3 Mar - 4 Mar
Hotel Attic 33
Grand Studio Suite, 1 King Bed, Hot Tub, Ground Floor

The Somos Bold Hotel

The Somos Bold Hotel
4.0 star property
El Poblado
9.4 out of 10, Exceptional, (241 reviews)
"Excellent!! Closed to everything. The room was clean and the hotel breakfast was delicious. Would definitely recommend!!"
United States
Joselyn
The price is €70
1 Mar - 2 Mar
The Somos Bold Hotel
Club Cabin, Accessible

Isak Hotel & Golf Airport

Isak Hotel & Golf Airport
3.0 star property
Rionegro
9.2 out of 10, Wonderful, (618 reviews)
"Hotel was nice, clean, great location near the airport and nice restaurants "
United States
Jessica
The price is €71
2 Mar - 3 Mar
Isak Hotel & Golf Airport
Outdoor pool, open 9:00 AM to 8:00 PM, pool umbrellas, pool loungers

Heiss Hotel By Jalo

Heiss Hotel By Jalo
4.0 star property
El Poblado
9.2 out of 10, Wonderful, (1,229 reviews)
"Very nice hotel and staff ! "
Canada
amelie
The price is €57
18 Mar - 19 Mar
Heiss Hotel By Jalo
Property grounds

Nomada Hotel Origen

Nomada Hotel Origen
3.0 star property
El Poblado
9.2 out of 10, Wonderful, (120 reviews)
"Lovely place, great service, awesome food!"
United States
Alejandro
The price is €58
10 Mar - 11 Mar
Nomada Hotel Origen
Breakfast, lunch, dinner served; international cuisine

Hotel Poblado Plaza

Hotel Poblado Plaza
3.5 star property
El Poblado
9.0 out of 10, Wonderful, (754 reviews)
"Very nice hotel "
United States
Yun
The price is €100
28 Feb - 1 Mar
Hotel Poblado Plaza
Daily cooked-to-order breakfast for a fee

Hotel Estelar Milla de Oro

Hotel Estelar Milla de Oro
3.5 star property
El Poblado
9.0 out of 10, Wonderful, (934 reviews)
"Very friendly staff and the hotel is a top class."
United States
Ariel
The price is €100
6 Mar - 7 Mar
Hotel Estelar Milla de Oro
Lobby sitting area

Hotel Lagoon

Hotel Lagoon
3.5 star property
Rionegro
9.2 out of 10, Wonderful, (321 reviews)
"Delicious food, attentive staff. "
United States
MARIA
Hotel Lagoon
Superior Double Room, 1 King Bed

1616 HOTEL

1616 HOTEL
3.5 star property
El Poblado
9.4 out of 10, Exceptional, (192 reviews)
"Great staff! "
United States
Michael
1616 HOTEL
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santa Cruz Hotel Reviews

Landmark Hotel

Landmark Hotel

10/10 Excellent
"Everything was good very clean very nice close to alot of thing if i go back i will go back there for sure and the pool on the roof i give it a 10 out of 10 i give a 15 "
Ruth Xiomara Melara 3-night trip
Posted 13 hours ago
Landmark Hotel

More cheap stays in Santa Cruz

Brana by Bernalo Hotel

Brana by Bernalo Hotel

77-46 Calle 42, Laureles Medellín
The price is €29 per night from 26 Mar to 27 Mar
€29
26 Mar - 27 Mar
9.2/10 Wonderful! (59 reviews)

Frequently asked questions

Where is the best place to stay in Santa Cruz?
Located 6.2 mi (10 km) from the heart of Santa Cruz, Calle Flora Hotel by Jalo is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Heiss Hotel By Jalo and Hotel Dorado La 70. See all available top hotels, or vacation rentals in Santa Cruz.
What are some of the best holiday rentals that Santa Cruz has to offer?
EP Casa Uribe Architecture Art & Nature: This holiday home rental outside Santa Cruz is located in a shopping district, and has an outdoor pool, a balcony and laundry facilities to put you at ease in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in Santa Cruz.
If I need to cancel my hotel reservation in Santa Cruz, will I receive a refund?
Yes! Most hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you booked a non-refundable reservation, you might be able to cancel it and receive a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.
What is staying in Santa Cruz like?
Visitors will definitely enjoy all that Santa Cruz has to offer. In Santa Cruz, there are 3 hotels and other accommodation options to choose from. Find out more about Santa Cruz.
What should I do while I'm visiting Santa Cruz?
Places to visit in the wider area include Medellin Botanical Garden, Arvi Park and Antioquia Museum. You'll also find Botero Plaza and Atanasio Giradot Stadium in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz guide.
How can I get around Santa Cruz?
Make your way to Andalucía MetroCable Station for metro travel. If you want to venture out around the area, you may want a rental car in Santa Cruz for your journey.
What's the seasonal weather in Santa Cruz?
The hottest months are usually August and July, with an average temperature of 19°C, while the coldest months are December and January, with an average of 18°C. The rainiest months in Santa Cruz are May, April, October and November, with each month seeing an average of 406 mm of rainfall.

Explore a world of travel with Expedia