Cairo Hotel Guide - Fort Defiance State Park hotels in Cairo, United States of America.

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Check prices for these dates

Tonight
15 Mar - 16 Mar
Tomorrow
16 Mar - 17 Mar
Next weekend
20 Mar - 22 Mar
In two weeks
27 Mar - 29 Mar

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Our top choices for Fort Defiance State Park hotels

Lobby

Quality Inn Cairo I-57

Quality Inn Cairo I-57
2.5 star property
7.8 km from Fort Defiance State Park
6.6 out of 10, (282 reviews)
"The room was somewhat clean, but that’s the best I can say. The door from outside to the hallway didn’t lock or even close all the way. No staff and the office closed 11pm-5am. Sketchy part of town. No eateries close by. I would not recommend. Didn’t feel safe but we were exhausted so we stayed."
United States
Tammie
The price is €66
includes taxes & fees
21 Mar - 22 Mar
Quality Inn Cairo I-57
Laptop workspace, blackout curtains, free cots/infant beds, free WiFi

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
17.5 km from Fort Defiance State Park
6.8 out of 10, (625 reviews)
"Affordable for a quick one night stay. Restaurant and gas station next to hotel."
United States
Annette
The price is €60
includes taxes & fees
29 Mar - 30 Mar
Super 8 by Wyndham Charleston/Sikeston East MO
Lobby sitting area

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
20.2 km from Fort Defiance State Park
6.8 out of 10, (409 reviews)
"The staff was very friendly and accommodating "
United States
Arturo
The price is €68
includes taxes & fees
16 Mar - 17 Mar
The Riverstone Hotel Charleston-Sikeston
Room, 1 King Bed, Non Smoking | View from room

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
16.2 km from Fort Defiance State Park
6.6 out of 10, (105 reviews)
"Convenient "
United States
Marcelle
The price is €62
includes taxes & fees
29 Mar - 30 Mar
Eagle Inn Charleston
Basic Double Room | Living area

La Center Motel

La Center Motel
2.0 star property
17.5 km from Fort Defiance State Park
7.6 out of 10, Good, (18 reviews)
"Quiet and convenient."
United States
Alma
The price is €55
includes taxes & fees
16 Mar - 17 Mar
La Center Motel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Fort Defiance State Park Hotel Reviews

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

10/10 Excellent
"Very nice room, we stayed in a queen suite, clean everything clean would stay again...im picky on hotel cleanliness and this was nice and also quiet. Great location "
Lisa 1-night trip
Posted 6 hours ago
Days Inn and Suites by Wyndham Sikeston

Hotels near other Fort Defiance State Park attractions

Columbus-Belmont State Park

3.7/5 (18 reviews)
You can learn about the history of Columbus when you stop by Columbus-Belmont State Park.
See properties

Ullin City Hall

After visiting Ullin City Hall, make a plan to see the other sights and activities in Ullin. Amble around the area's parks or experience its museums.
See properties

Frequently asked questions

What's the area like around Fort Defiance State Park?
Fort Defiance State Park is located in Cairo. When you want to settle in and find a place to stay, take a look at some of the hotels and other accommodation options that Expedia offers in the area.
What's the best place to stay close to Fort Defiance State Park?
The Riverstone Hotel Charleston-Sikeston is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. You'll find it 12.6 mi (20.2 km) from Fort Defiance State Park. Other good choices around the area include Super 8 by Wyndham Charleston/Sikeston East MO and Drury Inn & Suites Sikeston, MO.
If I need to cancel the hotel reservation for my stay near Fort Defiance State Park, will I receive a refund?
Yes! The majority of hotel room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your check-in date. If your reservation is non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best deals available near Fort Defiance State Park.