Jackson Hotel Guide - Casino Hotels in Jackson, Missouri

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Our top choices for Jackson hotels with a casino

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
8.8 out of 10, Excellent, (679)
"Great place "
United States
GUY
The price is €77
includes taxes & fees
7 Jan - 8 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (479)
"The room was clean and the mattress was extremely comfortable "
United States
Stacy
The price is €92
includes taxes & fees
4 Jan - 5 Jan 2026
The Riverview

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (469)
"Very nice hotel within walking distance to many good restaurants "
United States
Vicky
The price is €120
includes taxes & fees
11 Jan - 12 Jan 2026
Courtyard by Marriott Cape Girardeau Downtown

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!
Makanda
9.6 out of 10, Exceptional, (40)
"The cabin was perfect for our 5 nights in the area. There was plenty of room and everything we needed. The pictures online were nice but in real life, it was a real gem. Can't wait to visit again."
United States
Victoria H.
The price is €186
includes taxes & fees
31 Dec - 1 Jan 2026
Winetrail Cabin - SIU, Giant City SP, Shawnee Forest, & Cedar Lake minutes away!

Rockwood Inn

Rockwood Inn
2.0 star property
Cape Girardeau
10.0 out of 10, Exceptional, (19)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is €158
includes taxes & fees
6 Jan - 7 Jan 2026
Rockwood Inn

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (405)
"Very clean, courteus staff. Beautiful area and quiet. Very relaxing."
United States
Tommy
The price is €177
includes taxes & fees
31 Dec - 1 Jan 2026
Rest, Relax and Renew. Our log cabin experience awaits your arrival.

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (60)
"The property was extremely clean and well cared for.would definitely stay again. "
United States
Dan H.
The price is €159
includes taxes & fees
31 Dec - 1 Jan 2026
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

Serenity South -- Gardens, River-Views, and Refreshing Space

Serenity South -- Gardens, River-Views, and Refreshing Space
Cape Girardeau
10.0 out of 10, Exceptional, (149)
"Such a great place and location"
United States
Tracy H.
The price is €214
includes taxes & fees
2 Jan - 3 Jan 2026
Serenity South -- Gardens, River-Views, and Refreshing Space

Contemporary Glamping with Native American Appeal

Contemporary Glamping with Native American Appeal
Anna
9.8 out of 10, Exceptional, (155)
"Our 2nd time staying here and it was perfect"
United States
machelle p.
Contemporary Glamping with Native American Appeal

Magical Victorian near hiking / wine trail

Magical Victorian near hiking / wine trail
Anna
10.0 out of 10, Exceptional, (4)
"The house was beautiful! We were in awe of the decor and layout. This is a must-stay if you are in southern Illinois!"
United States
Lori C.
The price is €326
includes taxes & fees
2 Jan - 3 Jan 2026
Magical Victorian near hiking / wine trail
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Jackson Hotel Reviews

Frequently asked questions

Searching for casino hotels in Jackson?
If you're heading to Jackson for some gaming, you can play your hand at Isle Casino Cape Girardeau, located 9.5 mi (15.2 km) away, though it's not the only place worth visiting while you're here. Visitors enjoy the family-friendly activities and dining options in this destination.
How many hotels that are good for gaming will I find in Jackson?
You won't need a stroke of luck to find something that suits with one of Expedia's 12 lodging options in Jackson.
When should I take my casino trip to Jackson?
You might spend a lot of your holiday inside, but if you're planning to venture beyond the casino, looking at local weather trends is a good idea. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 4°C. Average annual precipitation for Jackson is 1439 mm.
What is there to do in Jackson?
You'll find attractions to visit in the area such as Lazy L Safari Park and Cape Girardeau Conservation Nature Center. Places to get outdoors include Lake Boutin, Little Grand Canyon Trail Trailhead and Shawnee National Forest. In addition, you might want to add Trail of Tears State Park and Mississippi River to your list.
What are my transportation options for my casino getaway to Jackson?
Here are some transportation options in Jackson: You can arrange a flight to the nearest airport, which is Cape Girardeau, MO (CGI-Cape Girardeau Municipal), 12.1 mi (19.5 km) from the city centre. If you'd like to explore around the area, you may want to rent a car for your trip.