Lake Nona Medical City Holidays

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Price found within the past 48 hours. Click for updated prices.
Orlando International Drive North Hotel

Orlando International Drive North Hotel

2 out of 5
International Drive District
Price was €1,095, price is now €1,049 per person
€1,049
per person
28 Mar - 31 Mar
found 21 hours ago
Return flight included
Dublin (DUB) to Orlando (MCO)
7.2/10 Good! (2,355 reviews)
La habitación muy limpia, el personal siempre atento

Reviewed on 10 Feb 2026

Florida Hotel & Conference Center in the Florida Mall

Florida Hotel & Conference Center in the Florida Mall

3.5 out of 5
Price was €1,374, price is now €1,132 per person
€1,132
per person
28 Mar - 31 Mar
found 21 hours ago
Return direct flight included
Dublin (DUB) to Orlando (MCO)
9.2/10 Wonderful! (2,232 reviews)
Check in was easy, room was very clean and the hotel was quiet. Great location for shopping.

Reviewed on 9 Feb 2026

The Delaney Hotel

The Delaney Hotel

3.5 out of 5
South Orange
Price was €1,367, price is now €1,192 per person
€1,192
per person
28 Mar - 31 Mar
found 21 hours ago
Return flight included
Dublin (DUB) to Orlando (MCO)
9.6/10 Exceptional! (1,002 reviews)
Great option but a little bit expensive

Reviewed on 9 Feb 2026

Hyatt Regency Orlando

Hyatt Regency Orlando

4.5 out of 5
International Drive District
Price was €1,355, price is now €1,227 per person
€1,227
per person
28 Mar - 31 Mar
found 21 hours ago
Return flight included
Dublin (DUB) to Orlando (MCO)
9.2/10 Wonderful! (1,828 reviews)
One the best hotels I have ever stayed in.

Reviewed on 8 Feb 2026

Spectrum Resort Villas Orlando and Waterparks

Spectrum Resort Villas Orlando and Waterparks

4 out of 5
Reunion
Price was €1,546, price is now €1,452 per person
€1,452
per person
28 Mar - 31 Mar
found 21 hours ago
Return flight included
Dublin (DUB) to Orlando (MCO)
9.2/10 Wonderful! (801 reviews)
The unit is clean and spacious with one bedroom with an ensuite bathroom and two bedrooms with a semi ensuite bathroom plus one toilet in the living room. One of the bathtub did not drain well, notified the front desk on the second day and someone came to fix it on the third day. The coffee machine was not working, someone came next evening to replace a new one. We have to park our vehicle a bit far from our unit since there are not enough parking space, I wonder tenants come in high season have to park far away. The front desk staffs are friendly. The water park and pickleball court is nearby and need to pay admission.

Reviewed on 7 Feb 2026

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most. Learn more about Lake Nona Medical City
International Drive showing landscape views

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Find hotels in International Drive District

Top hotels in Lake Nona Medical City

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando

4 out of 5
8800 Vistana Centre Dr Orlando FL
Fully refundableReserve now, pay when you stay
The price is €124 per night from 4 Mar to 5 Mar
€124
4 Mar - 5 Mar
includes taxes & fees
9.2/10 Wonderful! (4,560 reviews)
Amazing resort for the price you can’t beat it!

Reviewed on 10 Feb 2026

Sheraton Vistana Resort Villas, Lake Buena Vista/Orlando
Hyatt Regency Orlando International Airport

Hyatt Regency Orlando International Airport

4 out of 5
9300 Jeff Fuqua Boulevard Orlando FL
Fully refundableReserve now, pay when you stay
The price is €245 per night from 9 Mar to 10 Mar
€245
9 Mar - 10 Mar
includes taxes & fees
9.4/10 Exceptional! (3,995 reviews)
Great food in lobby bar ., very comfy room

Reviewed on 9 Feb 2026

Hyatt Regency Orlando International Airport
Universal's Cabana Bay Beach Resort

Universal's Cabana Bay Beach Resort

3.5 out of 5
6550 Adventure Way Orlando FL
Fully refundableReserve now, pay when you stay
The price is €133 per night from 10 Mar to 11 Mar
€133
10 Mar - 11 Mar
includes taxes & fees
8.8/10 Excellent! (6,298 reviews)
Freezing cold which was odd that it was so busy. But still cool.

Reviewed on 8 Feb 2026

Universal's Cabana Bay Beach Resort
See all 27,352 properties in Lake Nona Medical City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Lake Nona Medical City holiday package cost?
The cheapest Lake Nona Medical City package is €1,049, so your dream trip can become a reality — without burning a hole in your pocket. Combine flights, hotels and car rentals to tailor make a package that suits your travel style.
How do I get a cheap travel package to Lake Nona Medical City?
Find flights that fit your busy schedule, add a hotel to your booking and watch the savings rack up with a Lake Nona Medical City holiday package. It's as easy as that! From flights and hotels to tours and rental cars, Expedia makes travelling cheap and easy. And with more than 550 air carriers and 1,000,000 hotel options globally to pick from, you won't be short of choice.
Where should I stay in Lake Nona Medical City?
With loads to explore in Lake Nona Medical City, it'd be convenient for you to stay close to its attractions. Nemours Childrens Hospital, VA Medical Centre at Lake Nona and University of Central Florida College of Medicine are some fascinating ones to add to your to-do list.
What are the top hotels in Lake Nona Medical City?
Make a reservation at Residence Inn Orlando Lake Nona. It's one of the area's most sought-after properties. Another reputable option in Lake Nona Medical City is Courtyard Orlando Lake Nona.
How far in advance should I book my Lake Nona Medical City holiday?
It depends on the airline, but you can generally look up international fares on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper ticket just weeks prior to the date of departure.
What does an Expedia Lake Nona Medical City travel package include?
Expedia has everything you need to organise your Lake Nona Medical City getaway, but what goes into your package is totally up to you. Choose from a combination of hotels, rental cars and flights. In search of some experiences or tours to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a deal to match your needs.
What should I know before booking a Lake Nona Medical City travel package?
Locking in all the parts of your escape together is a great way to save. Combine your airfares, rental cars and hotels into one package. But hotels aren't your only option. Expedia has all types of properties, including holiday rentals like beachside villas and city apartments. The list goes on!
Can I choose my airline with a Lake Nona Medical City Expedia holiday package?
Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our holiday packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.
If I'm not able to travel, can I cancel my Lake Nona Medical City holiday package?
Don't worry if you're rethinking your Lake Nona Medical City holiday package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We know life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

Things to do

Universal Orlando Resort

Universal Orlando Resort Theme Park Tickets

€486
per adult
92% of travellers recommend
Universal Orlando Resort Theme Park Tickets
Aquatica Orlando

Aquatica Orlando

€44
per traveller
84% of travellers recommend
Aquatica Orlando
Florida: 90 Minute Everglades Cruise

Florida: 90 Minute Everglades Cruise

€46
per adult
100% of travellers recommend
Florida: 90 Minute Everglades Cruise
See all activities in Orlando
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.