Orlando Hotel Guide. Hotels in Lake Nona Medical City, Orlando, United States of America
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Our top choices for Lake Nona Medical City hotels
9.6 out of 10, Exceptional, (598)
"Mya, at the front desk, was exceptional and was a great start to our experience!"
James
The price is €147
includes taxes & fees
4 Jan - 5 Jan 2026
9.8 out of 10, Exceptional, (282)
"Our stay was great!"
Kendra
The price is €133
includes taxes & fees
4 Jan - 5 Jan 2026
9.6 out of 10, Exceptional, (326)
"Very clean hotel and spacious room with comfortable seating and kitchen area. The location was great for me as I was there visiting someone in an area hospital. There are also restaurants and coffee shops right outside the entrance. "
Sharon
The price is €181
includes taxes & fees
18 Jan - 19 Jan 2026
8.6 out of 10, Excellent, (1580)
"was a very nice stay"
Taylor Elaine
The price is €121
includes taxes & fees
11 Jan - 12 Jan 2026
9.6 out of 10, Exceptional, (1041)
"Everything about the Delaney Hotel was absolutely amazing!!!!"
Tara
Wyndham Lake Buena Vista – Disney Springs® Area
Wyndham Lake Buena Vista – Disney Springs® Area23.2 km from Lake Nona Medical City
8.8 out of 10, Excellent, (2797)
"Very conveniently located to Disney Springs, clean rooms and grounds, and very friendly service."
Todd
The price is €138
includes taxes & fees
4 Jan - 5 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Lake Nona Medical City
Find the best Lake Nona Medical City areas for the activities you enjoy most.
International Drive District
Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.
Photo by ©Disney
Open Photo by ©Disney
Bay Lake
Exciting theme parks plentiful wildlife and top sights from Epcot® to Walt Disney World® Resort – discover Bay Lake, a destination also famous for its entertainment.
Florida Center
If you're spending some time in Florida Center, Universal Orlando Resort and Universal Studios Florida are top sights worth seeing.
Champions Gate
Ample dining options and top golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.
Downtown Orlando
One of the most popular neighborhoods in Florida, this bustling area is full of art galleries, shops, bars and restaurants.
Top Lake Nona Medical City Hotel Reviews
CoCo Key Hotel and Water Resort
10/10 Excellent
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