St. Louis Hotel Guide - Lewis and Clark Interpretive Center hotels in St. Louis, United States of America.

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27 Dec - 28 Dec
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Lewis and Clark Interpretive Center hotels

Lobby lounge
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City

Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
2.5 star property
6.2 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (488)
"This hotel was well kept,the breakfast was excellent. Stsff was friendly. "
United States
Dennis M
The price is €105
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites St. Louis Pontoon Beach/Granite City
Lobby sitting area
Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach

Best Western Plus Pontoon Beach
3.0 star property
6.8 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (805)
"Staff and very nice, good breakfast, soft bed…. I would definitely stay again "
United States
LaSonya
The price is €81
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Pontoon Beach
Exterior
Bel Air Motel

Bel Air Motel

Bel Air Motel
3.5 star property
6.3 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (196)
"Great place super clean. Only thing missing no coffee and our room could have had a nice bistro table to sit at"
United States
James
The price is €82
includes taxes & fees
28 Dec - 29 Dec
Bel Air Motel
Blackout curtains, free WiFi, bed sheets
Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach

Red Lion Inn & Suites Pontoon Beach
2.5 star property
5.5 km from Lewis and Clark Interpretive Center
7.8 out of 10, Good, (577)
"Yes, very good, yes good breakfast, yes truck parking."
United States
mark
The price is €56
includes taxes & fees
30 Dec - 31 Dec
Red Lion Inn & Suites Pontoon Beach
Free daily buffet breakfast
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
10.9 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (822)
"Always a good stay here!"
United States
Chelsie
The price is €113
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Edwardsville by IHG
Lobby
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
9.4 km from Lewis and Clark Interpretive Center
8.4 out of 10, Very good, (808)
"Great staff, breakfast was excellent and rooms were clean"
United States
Carlos
The price is €98
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn Edwardsville - St. Louis
Gazebo
Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
10.8 km from Lewis and Clark Interpretive Center
8.6 out of 10, Excellent, (649)
"The room was very clean and the staff is always friendly "
United States
Lynn
The price is €89
includes taxes & fees
5 Jan - 6 Jan 2026
Country Hearth Inn & Suites Edwardsville St. Louis
Free daily self-service breakfast
La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach

La Quinta Inn & Suites by Wyndham Pontoon Beach
3.0 star property
6.9 km from Lewis and Clark Interpretive Center
7.6 out of 10, Good, (514)
"The hotel staff was exceptionally accommodating. Would stay here over anywhere in the area. "
United States
Kari
The price is €85
includes taxes & fees
28 Dec - 29 Dec
La Quinta Inn & Suites by Wyndham Pontoon Beach
BBQ/picnic Area
TownePlace Suites by Marriott St. Louis Edwardsville, IL

TownePlace Suites by Marriott St. Louis Edwardsville, IL

TownePlace Suites by Marriott St. Louis Edwardsville, IL
3.5 star property
10.9 km from Lewis and Clark Interpretive Center
9.0 out of 10, Wonderful, (195)
"The property was amazing. Loved the layout of the room and the desk than roles out, kitchenette and spacious bathroom. Only think missing was hot chocolate!"
United States
Stuart
The price is €165
includes taxes & fees
2 Jan - 3 Jan 2026
TownePlace Suites by Marriott St. Louis Edwardsville, IL
Premium bedding, pillow-top beds, blackout curtains, iron/ironing board
Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis

Econo Lodge Inn & Suites Granite City - St. Louis
2.0 star property
4.7 km from Lewis and Clark Interpretive Center
6.2 out of 10, (246)
"Overall the stay was adequate, right off the highway so convenient."
United States
Henry
The price is €65
includes taxes & fees
4 Jan - 5 Jan 2026
Econo Lodge Inn & Suites Granite City - St. Louis
Lobby
Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach

Days Inn by Wyndham Pontoon Beach
2.0 star property
6.6 km from Lewis and Clark Interpretive Center
6.2 out of 10, (571)
"Bed was soooooooo comfortable and front desk guy that checked me in was great as well "
United States
Maurice
The price is €61
includes taxes & fees
7 Jan - 8 Jan 2026
Days Inn by Wyndham Pontoon Beach
Exterior
Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area

Budget Motel Granite City/St Louis Area
2.0 star property
4.7 km from Lewis and Clark Interpretive Center
6.4 out of 10, (15)
"Its nice here"
United States
Sheila
The price is €62
includes taxes & fees
8 Jan - 9 Jan 2026
Budget Motel Granite City/St Louis Area
Reception
Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville

Hampton Inn & Suites St. Louis-Edwardsville
2.5 star property
10.1 km from Lewis and Clark Interpretive Center
7.4 out of 10, Good, (72)
"We enjoyed our stay"
United States
Susan
The price is €101
includes taxes & fees
3 Jan - 4 Jan 2026
Hampton Inn & Suites St. Louis-Edwardsville
Lobby
Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville

Drury Inn & Suites St. Louis Collinsville
3.0 star property
15.4 km from Lewis and Clark Interpretive Center
9.6 out of 10, Exceptional, (1001)
"Nice to have food and drinks provided "
United States
MICHAEL
The price is €96
includes taxes & fees
11 Jan - 12 Jan 2026
Drury Inn & Suites St. Louis Collinsville
Exterior
Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton

Hampton Inn & Suites St. Louis/Alton
2.5 star property
14 km from Lewis and Clark Interpretive Center
9.0 out of 10, Wonderful, (644)
"The staff were very professional and friendly. The breakfast had a great selection."
United States
Melissa
The price is €110
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites St. Louis/Alton
Exterior
Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area

Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area

Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
2.0 star property
6.7 km from Lewis and Clark Interpretive Center
5.6 out of 10, (657)
"It was good "
United States
Todd
The price is €58
includes taxes & fees
7 Jan - 8 Jan 2026
Super 8 by Wyndham Pontoon Beach IL/St. Louis MO Area
Lobby
Americas Best Value Inn Collinsville St. Louis

Americas Best Value Inn Collinsville St. Louis

Americas Best Value Inn Collinsville St. Louis
2.0 star property
15.8 km from Lewis and Clark Interpretive Center
6.4 out of 10, (943)
"Was a great place to stay "
United States
Eddei
The price is €57
includes taxes & fees
28 Dec - 29 Dec
Americas Best Value Inn Collinsville St. Louis
Free daily buffet breakfast
Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG

Holiday Inn Express and Suites Alton St Louis Area by IHG
2.5 star property
13.8 km from Lewis and Clark Interpretive Center
9.2 out of 10, Wonderful, (163)
"Staff and location were perfect"
United States
Ileta
The price is €114
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express and Suites Alton St Louis Area by IHG
Lobby sitting area
First Western Inn

First Western Inn

First Western Inn
2.0 star property
18.1 km from Lewis and Clark Interpretive Center
6.4 out of 10, (362)
"It was a good trip check in was fast and room are very clean"
United States
Letonjalyn
The price is €64
includes taxes & fees
9 Jan - 10 Jan 2026
First Western Inn
Lobby
The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel

The Great Rivers, an Ascend Collection Hotel
3.0 star property
11.5 km from Lewis and Clark Interpretive Center
7.8 out of 10, Good, (762)
"The hotel is being remodeled, so it's hard to give it a fair review."
United States
Stephen
The price is €81
includes taxes & fees
18 Jan - 19 Jan 2026
The Great Rivers, an Ascend Collection Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lewis and Clark Interpretive Center Hotel Reviews

Four Seasons Hotel St Louis

Four Seasons Hotel St Louis

10/10 Excellent
"Didn’t have breakfast "
Rodrick 1-night trip
Posted 4 days ago
Four Seasons Hotel St Louis

Hotels near other Lewis and Clark Interpretive Center attractions

Lewis and Clark Confluence Tower

Bring a camera when you climb this tower, which offers fantastic views across the Mississippi River and provides insight into a fascinating piece of history.
See properties

Lewis and Clark State Memorial Park

Explore the great outdoors at Lewis and Clark State Memorial Park, a lovely green space in Hartford. Discover the area's museums and monuments.
See properties

Frequently asked questions

What's the area like around Lewis and Clark Interpretive Center?
Lewis and Clark Interpretive Center is located in a welcoming area of Hartford that travellers like for its sporting events. You'll find 13 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay close to Lewis and Clark Interpretive Center?
Best Western Plus Pontoon Beach is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located 4.2 mi (6.8 km) from Lewis and Clark Interpretive Center. Other good options around the area include Hyatt Regency St. Louis at The Arch and Hampton Inn St. Louis-Downtown (At the Gateway Arch).
How many hotels will I find close to Lewis and Clark Interpretive Center?
Expedia has 13 hotels and other accommodation options a few miles from Lewis and Clark Interpretive Center.
If I need to cancel the hotel reservation for my stay near Lewis and Clark Interpretive Center, will I receive a refund?
Yes! The majority of hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals available near Lewis and Clark Interpretive Center.
What can I see and do near Lewis and Clark Interpretive Center?
You might spend a leisurely day outdoors at Lewis and Clark State Memorial Park and Dads Club Park. Create some family memories at CP Pinball and Saint Louis Zoo WildCare Park. Explore nature at Jones-Confluence Point State Park and Columbia Bottom Conservation Area.