Matlacha Isles Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €900 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Matlacha Isles

Find the best Matlacha Isles areas and neighborhoods for the activities you enjoy most. Learn more about Matlacha Isles
Vögel an der Westküste Floridas

Pelican

1 out of top 10 points of interest in this area
4/5(1 area review)

While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

Find hotels in Pelican

Top hotels in Matlacha Isles

Margaritaville Beach Resort Fort Myers

Margaritaville Beach Resort Fort Myers

4 out of 5
251 Crescent Street Fort Myers Beach FL
The price is €255 per night from 26 May to 27 May
€255
26 May - 27 May
includes taxes & fees
9/10 Wonderful! (2,070 reviews)
Amazing place! The beach was absolutely breathtaking, rooms were clean and the staff was friendly. I would definitely recommend this as a getway!

Reviewed on 7 May 2026

Margaritaville Beach Resort Fort Myers
Sanibel Island Beach Resort

Sanibel Island Beach Resort

3 out of 5
1231 Middle Gulf Dr Sanibel FL
Fully refundableReserve now, pay when you stay
The price is €267 per night from 1 Jun to 2 Jun
€267
1 Jun - 2 Jun
includes taxes & fees
9.2/10 Wonderful! (1,867 reviews)
The resort was very cute. The rooms were basic, but well maintained. Everything functioned properly and was comfortable. The pool and bar were very nice areas. The staff at the bar were very helpful and kind. It was nice to have a seashell washing station and an outdoor shower for washing off before ...

Reviewed on 6 May 2026

Sanibel Island Beach Resort
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

3.5 out of 5
1400 Estero Blvd Fort Myers Beach FL
Fully refundableReserve now, pay when you stay
The price is €172 per night from 12 May to 13 May
€172
12 May - 13 May
includes taxes & fees
9/10 Wonderful! (1,458 reviews)
I really like staying there over there for three nights. The beds were comfortable and clean and the staff was really nice reminded me of the the '70s Florida look. And also the breakfast at the Rooftop restaurant was amazing. I would rate it a 10 for sure

Reviewed on 6 May 2026

Lani Kai Beachfront Resort
See all 14,451 properties in Matlacha Isles
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Matlacha Isles holiday package cost?
Our Matlacha Isles holiday packages, which begin from just , are the best way to save loads of cash. Select your favourite flights, hotels and rental cars to create a custom-built itinerary.
How do I get a cheap travel package to Matlacha Isles?
Combine your hotel and flight bookings, add on extras such as activities, and save with a Matlacha Isles holiday package. You won't just walk away with awesome discounts on your trip — you'll have loads of choice at your fingertips too. When you book through Expedia, you'll have your pick of over 550 partner airlines and 1,000,000 hotels around the globe. Your next epic adventure begins right here, right now!
Where should I stay in Matlacha Isles?
If you're itching to be where the action is, stay near Sun Splash Water Park. Many happy campers book a hotel around this renowned tourist attraction.
What are the top hotels in Matlacha Isles?
Reserve a room at The Perfect Day In Matlacha Direct Gulf Access. It's one of the neighbourhood's most popular hotels. Another highly rated option in Matlacha Isles is Fun'n Sun - Charming 3 Br/ 3 Baths Waterfront Villa W. Boat Lift.
How far in advance should I book my Matlacha Isles holiday?
Smart travellers will likely want to reserve their seats early. You can normally start comparing international fares on Expedia up to a year before your intended flight. If you've left things to the last minute, don't stress. Low prices occasionally become available just weeks prior to departure.
What does an Expedia Matlacha Isles travel package include?
Expedia has all you need to organise your Matlacha Isles trip, but how you structure your package depends on you. Select from a combination of rental cars, hotels and flights. Chasing some experiences or tours to keep you busy? Once you've made your booking, you can add them on too. No matter your budget, there's a deal to suit your needs.
What should I know before booking a Matlacha Isles travel package?
Bundling your bookings into a Matlacha Isles holiday package is the easiest way to organise your trip. Not only that, you'll save just for combining your hotels, flights and car rentals. Once you've booked, why not add on a day tour or an activity?
Can I choose my airline with a Matlacha Isles Expedia holiday package?
Yes, definitely. Expedia has more than 550 partner airlines to select from globally. With all that choice, finding the ideal carrier to bring you to Matlacha Isles will be easy.
If I'm not able to travel, can I cancel my Matlacha Isles holiday package?
Don't worry if you're rethinking your Matlacha Isles holiday package — you can cancel or change your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur charges from your airline, hotel or car rental company. We get that your circumstances can suddenly change, so look up our Customer Service Portal if that happens. When you're ready to make changes, we're ready to help.

Popular places to visit

A Cute diverse boy and little girl running and splashing together holding hands in the large swimming pool resort while on a family vacation

Sun Splash Water Park

Enjoy a fun-filled day at Sun Splash Water Park during your visit to Cape Coral. Stroll along the marina or discover the beautiful sunsets in this family-friendly area.

Sun Splash Water Park

Royal Tee Golf Club

Enjoy a round of golf in Cape Coral at Royal Tee Golf Club. Wander the beautiful beaches and marina in the area.

Royal Tee Golf Club

Coral Oaks Golf Course

Enjoy a round of golf in Cape Coral at Coral Oaks Golf Course. Stroll along the area's marina or simply savour its lively bars.

Coral Oaks Golf Course

Things to do

Copacetic Day Sail

Copacetic Day Sail

€60
per adult
100% of travellers recommend
Copacetic Day Sail
Southwest Florida Sunset Sail

Southwest Florida Sunset Sail

€60
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
Dolphin Wildlife Cruise Fort Myers Beach

Dolphin Wildlife Cruise Fort Myers Beach

€55
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
See all activities in Cape Coral
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.