
Cape Coral Hotel Guide. Hotels in Matlacha Isles, Cape Coral, United States of America
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Check prices for these dates
Our top choices for Matlacha Isles hotels

HomeTowne Studios by Red Roof Fort Myers
HomeTowne Studios by Red Roof Fort Myers21.7 km from Matlacha Isles
The price is €64
includes taxes & fees
15 May - 16 May

Lani Kai Beachfront Resort
Lani Kai Beachfront Resort23.2 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,458 reviews)
The price is €172
includes taxes & fees
12 May - 13 May

Holiday Inn Express & Suites Fort Myers Airport by IHG
Holiday Inn Express & Suites Fort Myers Airport by IHG29 km from Matlacha Isles
9.6 out of 10, Exceptional, (1,021 reviews)
The price is €94
includes taxes & fees
9 May - 10 May

The Bay Inn at Lani Kai
The Bay Inn at Lani Kai23.1 km from Matlacha Isles
7.6 out of 10, Good, (401 reviews)
The price is €129
includes taxes & fees
10 May - 11 May

Pink Shell Beach Resort and Marina
Pink Shell Beach Resort and Marina21.7 km from Matlacha Isles
9.4 out of 10, Exceptional, (1,343 reviews)
The price is €277
includes taxes & fees
26 May - 27 May

StudioRes by Marriott Fort Myers Airport
StudioRes by Marriott Fort Myers Airport29.5 km from Matlacha Isles
9.4 out of 10, Exceptional, (53 reviews)
The price is €80
includes taxes & fees
13 May - 14 May

Comfort Suites Fort Myers East I-75
Comfort Suites Fort Myers East I-7524.8 km from Matlacha Isles
9.6 out of 10, Exceptional, (453 reviews)
The price is €84
includes taxes & fees
7 Jun - 8 Jun

Park Motel
Park MotelDiplomat, 17.2 km from Matlacha Isles
9.2 out of 10, Wonderful, (46 reviews)
The price is €90
includes taxes & fees
10 May - 11 May

Comfort Inn Fort Myers Northeast
Comfort Inn Fort Myers Northeast25.8 km from Matlacha Isles
7.8 out of 10, Good, (728 reviews)
The price is €71
includes taxes & fees
7 Jun - 8 Jun

1 Island Hideaway
1 Island Hideaway25.1 km from Matlacha Isles
8.6 out of 10, Excellent, (32 reviews)
The price is €378
includes taxes & fees
10 May - 11 May

Sanibel Island Beach Resort
Sanibel Island Beach Resort22.7 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,867 reviews)
The price is €267
includes taxes & fees
1 Jun - 2 Jun

TownePlace Suites by Marriott Fort Myers Gulf Coast
TownePlace Suites by Marriott Fort Myers Gulf Coast29.9 km from Matlacha Isles
9.2 out of 10, Wonderful, (190 reviews)
The price is €104
includes taxes & fees
1 Jun - 2 Jun

Pointe Estero Beach Resort
Pointe Estero Beach Resort28.6 km from Matlacha Isles
9.2 out of 10, Wonderful, (1,006 reviews)
The price is €430
includes taxes & fees
12 May - 13 May

Baymont by Wyndham Punta Gorda/Port Charlotte
Baymont by Wyndham Punta Gorda/Port Charlotte28.9 km from Matlacha Isles
8.4 out of 10, Very good, (1,214 reviews)
The price is €68
includes taxes & fees
11 May - 12 May

The Anchor Inn
The Anchor Inn21.8 km from Matlacha Isles
10.0 out of 10, Exceptional, (32 reviews)
The price is €201
includes taxes & fees
31 May - 1 Jun

Quality Suites Fort Myers I-75
Quality Suites Fort Myers I-7527.1 km from Matlacha Isles
8.4 out of 10, Very good, (1,007 reviews)
The price is €59
includes taxes & fees
7 Jun - 8 Jun

Extended Stay America Premier Suites - Fort Myers - Airport
Extended Stay America Premier Suites - Fort Myers - Airport23.6 km from Matlacha Isles
8.8 out of 10, Excellent, (973 reviews)
The price is €56
includes taxes & fees
10 May - 11 May

Hampton Inn Fort Myers-Airport & I-75
Hampton Inn Fort Myers-Airport & I-7526.8 km from Matlacha Isles
9.0 out of 10, Wonderful, (1,005 reviews)
The price is €92
includes taxes & fees
24 May - 25 May

Latitude 26 Waterfront Resort & Marina
Latitude 26 Waterfront Resort & Marina20.3 km from Matlacha Isles
8.6 out of 10, Excellent, (1,005 reviews)
The price is €104
includes taxes & fees
10 May - 11 May

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park28 km from Matlacha Isles
8.0 out of 10, Very good, (1,680 reviews)
The price is €66
includes taxes & fees
17 May - 18 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.

Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.

Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.

Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.

Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Sun Splash Water Park.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
Top Matlacha Isles Hotel Reviews

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
10/10 Excellent

















































































