Matthews Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Matthews hotels

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (786 reviews)
"We were very satisfied with our stay. We will make this a regular stay when traveling to or from Iowa."
United States
Carolyn
The price is €66
includes taxes & fees
8 Jun - 9 Jun
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.6 out of 10, Exceptional, (1,005 reviews)
"Breakfast was good,pool hot tub excellent "
United States
Janica
The price is €111
includes taxes & fees
4 Jul - 5 Jul
Drury Inn & Suites Sikeston, MO

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (767 reviews)
"Great stay with Great people, very clean and welcoming"
United States
Mircea
The price is €53
includes taxes & fees
7 Jun - 8 Jun
New Orleans Inn Portageville

The Riverstone Hotel Charleston-Sikeston

The Riverstone Hotel Charleston-Sikeston
2.5 star property
Charleston
6.8 out of 10, (413 reviews)
"All very just okay "
United States
Sherry
The price is €72
includes taxes & fees
8 Jun - 9 Jun
The Riverstone Hotel Charleston-Sikeston

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (84 reviews)
"Great stay, kind staff, very clean property."
United States
Joni
The price is €107
includes taxes & fees
28 Jun - 29 Jun
Fairfield Inn & Suites by Marriott Sikeston

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (637 reviews)
"Clean rooms,"
United States
Karl
The price is €57
includes taxes & fees
14 Jun - 15 Jun
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (64 reviews)
"Great hotel for the price!!! Remodel very nice and modern. "
United States
Amy
The price is €84
includes taxes & fees
6 Jun - 7 Jun
Super 8 By Wyndham Marston

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.8 out of 10, Exceptional, (36 reviews)
"The property was clean and the staff was friendly. "
United States
Shelia
The price is €101
includes taxes & fees
21 Jun - 22 Jun
Hampton Inn By Hilton Dexter

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (573 reviews)
"Very clean hotel with comfortable bedding. Front desk staff was very nice and accommodating as we were traveling with a small dog."
United States
Connie
The price is €103
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn Sikeston

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (1,004 reviews)
"Very convenient and staff was great."
United States
jeanne
The price is €90
includes taxes & fees
14 Jun - 15 Jun
Best Western Plus Sikeston I-55

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1,002 reviews)
"When I stay at hotels I like to find hotels like this one for the $$$ value . This hotel was clean and the bed was very comfortable. Room 237 . I didn’t hear any interstate noise . I didn’t eat the breakfast but the coffee was very good . I would stay here again ."
United States
Kurt
The price is €73
includes taxes & fees
17 Jun - 18 Jun
Days Inn and Suites by Wyndham Sikeston

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (466 reviews)
"Only stayed one night, no complaints"
United States
Zachary
The price is €104
includes taxes & fees
21 Jun - 22 Jun
Holiday Inn Express & Suites Sikeston Southwest by IHG

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (124 reviews)
"The room was great, TV was awesome. Staff was friendly."
United States
Stanley
The price is €47
includes taxes & fees
4 Jul - 5 Jul
Travel Inn Marston I-55 by Hotel O

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"Room was very nice and in very clean condition and hotel staff was very helpful and polite. The breakfast was very delicious and coffee served all day. The hotel smelled very nice and had a very welcoming feeling. Will definitely book with them again"
United States
Joseph
The price is €124
includes taxes & fees
25 Jun - 26 Jun
TownePlace Suites by Marriott Sikeston

Country Yard Inn and Suite

Country Yard Inn and Suite
2.0 star property
Sikeston
6.8 out of 10, (139 reviews)
"Enjoyed our stay. All the appliances worked and our air conditioner kept us cool! Will definitely stay here again!"
United States
Sheryl
The price is €58
includes taxes & fees
12 Jun - 13 Jun
Country Yard Inn and Suite

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.8 out of 10, (636 reviews)
"Staff, A/C, adequate breakfast"
United States
David
The price is €69
includes taxes & fees
7 Jun - 8 Jun
Super 8 by Wyndham Sikeston/Miner Area

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (263 reviews)
"Room was ok, I was there for 4 nights and they never even emptied the trash"
United States
Robert
The price is €49
includes taxes & fees
5 Jul - 6 Jul
Econo Lodge Dexter

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (348 reviews)
"Nice rooms, friendly staff, "
United States
Sarah
The price is €63
includes taxes & fees
29 Jun - 30 Jun
Dexter Inn

Eagle Inn Charleston

Eagle Inn Charleston
2.0 star property
Charleston
6.6 out of 10, (106 reviews)
"Great"
United States
Jackson
The price is €68
includes taxes & fees
7 Jun - 8 Jun
Eagle Inn Charleston

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (409 reviews)
"Clean room, staff was super helpful"
United States
Katherine
The price is €84
includes taxes & fees
7 Jun - 8 Jun
Travelodge by Wyndham Dexter
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Matthews Hotel Reviews

More cheap stays in Matthews

Frequently asked questions

Where is the best place for a stay in Matthews?
Drury Inn & Suites Sikeston, MO, located 9.7 mi (15.5 km) from the heart of Matthews, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Hampton Inn Sikeston and Best Western Plus Sikeston I-55. See all available top hotels, or vacation rentals in Matthews.
What are some of the best holiday rentals that Matthews has to offer?
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This holiday home rental outside of Matthews offers a fireplace, a balcony and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. See all vacation rentals in Matthews.
If I need to cancel my hotel reservation in Matthews, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Matthews.
How is it to stay in Matthews?
Travellers to Matthews will find plenty to explore and enjoy. There are 39 hotels and other accommodation options in the surrounding area. Find out more about Matthews.
What are the top places to visit in Matthews?
Places to visit in the wider area include Sikeston Depot Museum, Big Oak Tree State Park and Central Park. You'll also find River Ridge Winery and Hunter-Dawson State Historic Site in the area. Take a look at what more there is to see and do in Expedia's Matthews guide.
What's the seasonal weather in Matthews?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Matthews is 1533 mm.