Holiday Rentals in Mesilla

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Our top choices for Mesilla holiday rentals

9.4 out of 10, Exceptional, (17)
"Everything was great! We loved utilizing the outdoor kitchen and hot tub. It was very clean and well cared for. The couches were comfy for hanging out and the beds were great! "
United States
Lindsay A.
The price is €223
includes taxes & fees
4 Jan - 5 Jan 2026
Tuscan Villa Outdoor Living, Jacuzzi & Gym
10.0 out of 10, Exceptional, (1)
"We were unable to actually stay in the apartment since we came down with the flu right before our trip. However, communication with the host was easy, they were very responsive, and I will absolutely stay at one of their properties next time we are in Las Cruces. "
United States
Claire Z.
The price is €161
includes taxes & fees
9 Jan - 10 Jan 2026
Downtown Midcentury Studio+ 3 mins to Farmer`s Mkt
10.0 out of 10, Exceptional, (2)
"Wonderful property. Peace and quiet. Lots of wildlife. Worth the unpaved road to reach the property."
United States
Robert T.
The price is €158
includes taxes & fees
19 Jan - 20 Jan 2026
Studio w/queen bed, pets ok, 3 min to Farmer's mkt
10.0 out of 10, Exceptional, (21)
"I would stay here again. "
United States
Sara R.
The price is €235
includes taxes & fees
2 Jan - 3 Jan 2026
Southwest Gem just minutes from White Sands National Park
10.0 out of 10, Exceptional, (3)
"Wonderful nights sleep says it all - w hugs waiting in the kitchen kuerig coffee , eggs , English muffins to get us started on our way 10 stars "
United States
Anita S.
The price is €225
includes taxes & fees
3 Jan - 4 Jan 2026
2 bd/2bth near NMSU and Memorial Medical Center
3.0 star property
The price is €224
includes taxes & fees
2 Jan - 3 Jan 2026
Las Cruces Home w/ Fenced Yard: Recently Remodeled
10.0 out of 10, Exceptional, (11)
"Clean, comfortable, Garage access, "
United States
Richard
4098/Lyle SW · Brand New Home in Beautiful Golf Course Community
10.0 out of 10, Exceptional, (32)
"Easy booking/check in/check out - nice house, plenty of room for our sisters retreat - good location for shopping, meals and spa day - host is responsive "
United States
Margaret M.
Stylish & Comfy House with Backyard and Parking

Holiday Home in Las Cruces

Gardner Casita - Central Location
10.0 out of 10, Exceptional, (5)
"Clean,comfortable and cozy. We were close to everything when we needed to explore. Quiet neighborhood and parked in the driveway"
United States
Steve M.
The price is €293
includes taxes & fees
31 Jan - 1 Feb 2026
Gardner Casita - Central Location
2.0 star property
8.8 out of 10, Excellent, (3)
"Quiet Clean comfortable beds at a reasonable price "
United States
Timmi M.
Beautiful little Magnolia in Las Cruses
10.0 out of 10, Exceptional, (6)
"Beautiful home, really enjoyed our stay. Would recommend this home to others. "
United States
Darlyn G.
Desert Getaway - 3BR Home w/ Outdoor Kitchen & Spacious Patio
8.8 out of 10, Excellent, (13)
"Cute and quiet! Really enjoyed our stay and hope to stay again soon!"
United States
Michael B.
Modern 3-Bedroom Villa with Jacuzzi and Gym
9.6 out of 10, Exceptional, (11)
"We really enjoyed staying here. It was clean, the furnishings were really nice, the location was great and the hosts were excellent. We would stay here again."
United States
Marc R.
4014/Russ Modern · New Home in Quiet Neighborhood - Relax and Enjoy
10.0 out of 10, Exceptional, (20)
"Beautiful home, plenty of rooms. "
United States
Evelyn Z.
Comfy SW Home with Private Yard & Mountain Views!
9.6 out of 10, Exceptional, (5)
"I was truly impressed with my rental. It was extremely clean, quiet, comfortable and pleasant. The price was reasonable and we enjoyed it tremendously! Thank you John and Erica!!! My son enjoyed the popcorn. Hope to be renting this again soon!"
United States
Robert M.
The price is €133
includes taxes & fees
2 Jan - 3 Jan 2026
Charming 1-bedroom house with WiFi, AC Mesilla Park Las Cruces
9.2 out of 10, Wonderful, (10)
"Great location and very convenient. Worked well for our stay. Clean and convenient - just whaat we needed. Host was very helpful. "
United States
Keith R.
Centrally located Cozy RV with all the essentials in spacious secure gated area!

Holiday Home in Las Cruces

4 Bedroom Contemporary Model Home
9.2 out of 10, Wonderful, (31)
"Easy and close to campus. Nice home!"
United States
Casey T.
The price is €223
includes taxes & fees
9 Jan - 10 Jan 2026
4 Bedroom Contemporary Model Home
10.0 out of 10, Exceptional, (2)
"Great place!!! "
United States
Tera W.
The price is €222
includes taxes & fees
4 Jan - 5 Jan 2026
Elite Casita with EV Level II Charger & Indoor Jet Tub
10.0 out of 10, Exceptional, (1)
"Padma, the host, was very responsive to all messages and very helpful and supportive throughout the process. The property is self was fantastic! The interior was tastefully decorated with comfy furnishings. The patio (elevated deck) offers great views of the Oregon Mountains to the east and Las Cruses to the west. We loved drinking our morning coffee enjoying the views and planning our day. At night, the patio offered a spectacular view of the night sky. The volume of stars that were visible was...
United States
Robert B.
3/2 near University and Memorial Hospital
10.0 out of 10, Exceptional, (1)
"We liked the location and homey feeling. Nice to have a yard and chiminea, though we didn't use it this trip."
United States
Tom K.
2 bed, yard, pet friendly in Historic Mesilla.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesilla Hotel Reviews

Find out more about Mesilla

Everything you need to know about Mesilla holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Mesilla holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, apart-hotels, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Mesilla holiday rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Mesilla holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Mesilla. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Mesilla holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Mesilla holiday rentals we have selected for you start as low as €117 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Mesilla rentals

At Expedia, we put the best Mesilla holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Mesilla rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Mesilla holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Mesilla. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find a holiday rental in Mesilla?

Yes, there are holiday rentals close to the most popular sights in Mesilla, or you can select a more secluded option if you're looking for a relaxing stay. Mesilla is known for its restaurants and shopping. Make sure you have time to check out the theatres while you're in the area.

What are some of the best holiday rentals that Mesilla has to offer?

Casita Azul, Mesilla Plaza Only Steps Away: This highly rated holiday home rental in Mesilla is located on a lake, and has a patio, a BBQ and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. You and your friends and family can relax into your holiday with amenities such as a selection of books.

How many holiday rentals will I find in Mesilla?

With 9 Expedia holiday rentals, you're guaranteed to find just the right place for your Mesilla stay.

What’s there to see and do in Mesilla?

Cultural attractions include Fountain Theatre and Fountain Theater, whereas Rio Grande is one spot to enjoy nature. Other places in town to visit include Mesillia Plaza and San Albino Basilica.

What’s a holiday rental in Mesilla like?

Holiday rentals are private properties where you can stay for a few weeks, or just a few days, in Mesilla. Holiday rentals provide amenities like laundry facilities and kitchens so you'll have all the comforts of home. If you're concerned about cleanliness, a holiday rental can provide a sense of seclusion away from public hotel lifts and busy concierge desks while still allowing you to travel. You'll also find more space in a holiday rental than in a hotel, which is another reason why a holiday rental is a popular option for a family getaway.