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Mesilla Hotels

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Our top choices for Mesilla hotels

Lobby
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain

La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
3.0 star property
Las Cruces
8.2 out of 10, Very good, (2308)
"Great staff!! Small hotel,older, BUT close by everything!!!"
United States
deborah
The price is €58
includes taxes & fees
11 Jan - 12 Jan 2026
La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain
Exterior
Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces
2.5 star property
Las Cruces
8.2 out of 10, Very good, (1307)
"Friendly staff and spacious King room."
United States
Donald
The price is €50
includes taxes & fees
19 Jan - 20 Jan 2026
Days Inn by Wyndham Las Cruces
Restaurant
Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10

Hampton Inn & Suites Las Cruces I-10
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1001)
"Clean, great staff, comfortable rooms. "
United States
Lizette
The price is €88
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn & Suites Las Cruces I-10
Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, pool loungers
Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces

Hotel Encanto de Las Cruces
3.5 star property
Las Cruces
9.0 out of 10, Wonderful, (1612)
"Great location fun vibes "
United States
Joe
The price is €133
includes taxes & fees
7 Jan - 8 Jan 2026
Hotel Encanto de Las Cruces
Lobby
Motel 6 Las Cruces, NM - Telshor

Motel 6 Las Cruces, NM - Telshor

Motel 6 Las Cruces, NM - Telshor
2.0 star property
Las Cruces
7.2 out of 10, Good, (1000)
"Was a nice stay "
United States
Gerald
The price is €61
includes taxes & fees
3 Jan - 4 Jan 2026
Motel 6 Las Cruces, NM - Telshor
Business centre
Best Western Mission Inn

Best Western Mission Inn

Best Western Mission Inn
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1227)
"Rooms,staff, good location "
United States
Katsiaryna
The price is €79
includes taxes & fees
1 Jan - 2 Jan 2026
Best Western Mission Inn
Exterior
Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces

Ramada Hotel & Conference Center by Wyndham Las Cruces
3.0 star property
Las Cruces
8.0 out of 10, Very good, (1007)
"We love this hotel. It’s absolutely gorgeous. "
United States
Maria
The price is €74
includes taxes & fees
4 Jan - 5 Jan 2026
Ramada Hotel & Conference Center by Wyndham Las Cruces
Desk, laptop workspace, blackout curtains, soundproofing
Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area

Super 8 by Wyndham Las Cruces/White Sands Area
2.0 star property
Las Cruces
7.2 out of 10, Good, (1009)
"It was good. I would stay again "
United States
Douglas
The price is €47
includes taxes & fees
8 Jan - 9 Jan 2026
Super 8 by Wyndham Las Cruces/White Sands Area
Property amenity
Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces

Hilton Garden Inn Las Cruces
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (1001)
"Great stay"
United States
Myles
The price is €89
includes taxes & fees
11 Jan - 12 Jan 2026
Hilton Garden Inn Las Cruces
Restaurant
Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25

Hampton Inn & Suites Las Cruces I-25
2.5 star property
Las Cruces
8.4 out of 10, Very good, (1000)
"Great staff, coffee for guests."
United States
Valerie Isabelle
The price is €88
includes taxes & fees
19 Jan - 20 Jan 2026
Hampton Inn & Suites Las Cruces I-25
Property amenity
Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces

Drury Inn & Suites Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (1002)
"Clean room and food take great for dinner and breakfast."
United States
Lori
The price is €93
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites Las Cruces
Indoor pool
Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North

Comfort Suites Las Cruces I-25 North
2.5 star property
Las Cruces
9.2 out of 10, Wonderful, (1001)
"Clean room, friendly staff and good location"
United States
PHILIP
The price is €108
includes taxes & fees
29 Jan - 30 Jan 2026
Comfort Suites Las Cruces I-25 North
Exterior
Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG

Holiday Inn Express & Suites Las Cruces North by IHG
2.5 star property
Las Cruces
9.0 out of 10, Wonderful, (985)
"Staff is great rooms nice and clean "
United States
William
The price is €117
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Las Cruces North by IHG
Exterior
Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG

Staybridge Suites Las Cruces by IHG
3.0 star property
Las Cruces
8.8 out of 10, Excellent, (1003)
"Clean rooms with excellent breakfast. Great variety."
United States
SUBRAT SURYAKANT
The price is €94
includes taxes & fees
18 Jan - 19 Jan 2026
Staybridge Suites Las Cruces by IHG
Indoor pool
Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla

Comfort Inn & Suites Las Cruces Mesilla
2.5 star property
Las Cruces
8.8 out of 10, Excellent, (1002)
"Staff was courteous, rooms were comfortable. "
United States
Ronn
The price is €99
includes taxes & fees
18 Jan - 19 Jan 2026
Comfort Inn & Suites Las Cruces Mesilla
Lobby
Comfort Suites University Las Cruces

Comfort Suites University Las Cruces

Comfort Suites University Las Cruces
2.5 star property
Las Cruces
8.0 out of 10, Very good, (1003)
"Amazing staff, clean rooms, great breakfast "
United States
Michelle
The price is €79
includes taxes & fees
18 Jan - 19 Jan 2026
Comfort Suites University Las Cruces
Full-sized fridge, microwave, dishwasher, coffee/tea maker
Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces

Home2 Suites by Hilton Las Cruces
3.0 star property
Las Cruces
9.4 out of 10, Exceptional, (664)
"Room was spotless and staff was very professional."
United States
Friedrich
The price is €121
includes taxes & fees
31 Jan - 1 Feb 2026
Home2 Suites by Hilton Las Cruces
Property amenity
Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU

Courtyard by Marriott Las Cruces at NMSU
3.0 star property
Las Cruces
9.2 out of 10, Wonderful, (511)
"Courteous staff and clean rooms"
United States
David
The price is €128
includes taxes & fees
25 Jan - 26 Jan 2026
Courtyard by Marriott Las Cruces at NMSU
Pool
Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area

Quality Inn & Suites Las Cruces - University Area
2.5 star property
Las Cruces
7.0 out of 10, Good, (1001)
"Great place to stay "
United States
Derek
The price is €54
includes taxes & fees
19 Jan - 20 Jan 2026
Quality Inn & Suites Las Cruces - University Area
Terrace/patio
Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces

Towneplace Suites by Marriott Las Cruces
3.0 star property
Las Cruces
8.6 out of 10, Excellent, (144)
"Loved the suite with Full Kitchen! We also enjoyed the breakfast buffet and the pool!"
United States
LAURIE
The price is €108
includes taxes & fees
7 Jan - 8 Jan 2026
Towneplace Suites by Marriott Las Cruces
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Mesilla attractions

Mesillia Plaza

This National Historic Landmark features preserved 19th-century adobe architecture from the Gadsden Purchase era. Browse unique shops, savour authentic cuisine, and experience cultural events in this historic square.
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Fountain Theatre

New Mexico's oldest cinema, the Fountain Theatre has showcased independent films since 1905 in a historic adobe building. Enjoy art-house cinema with refreshments while admiring original desert murals.
See properties

Learn more about Mesilla

Historic adobe buildings surround the plaza where Billy the Kid once stood trial in this charming town. Explore local art galleries and sample authentic Mexican cuisine at La Posta, a restaurant housed in a 19th-century stagecoach stop.

See all hotels in Mesilla
Red chile doorway Mesilla NM

Top Mesilla Hotel Reviews

Best Western Mission Inn

Best Western Mission Inn

10/10 Excellent
"Very friendly staff! The bed was comfortable and the room was spacious."
Tamara 1-night trip
Posted 19 hours ago
Best Western Mission Inn

More cheap stays in Mesilla

Days Inn by Wyndham Las Cruces

Days Inn by Wyndham Las Cruces

755 Avenida De Mesilla Las Cruces NM
The price is €50 per night from 19 Jan to 20 Jan
€50
19 Jan - 20 Jan 2026
includes taxes & fees
8.2/10 Very Good! (1,307 reviews)

Frequently asked questions

What's the best place for a stay in Mesilla?
Located 4.5 mi (7.3 km) from the heart of Mesilla, Hotel Encanto de Las Cruces is a top choice for your stay, based on our traveller data. Other good choices for your visit to the area are La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces. See all available top hotels, or vacation rentals in Mesilla.
What are some of the best holiday rentals that Mesilla has to offer?
Casita Azul, Mesilla Plaza Only Steps Away: This highly rated holiday home rental in Mesilla is located on a lake, and has a patio, a BBQ and air conditioning to put you at ease in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. You and your friends and family can relax into your holiday with amenities such as a selection of books. See all vacation rentals in Mesilla.
If I need to cancel my hotel reservation in Mesilla, will I receive a refund?
Yes! You'll find that most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesilla.
What are some hotels with pools in Mesilla?
Hotel Encanto de Las Cruces: Hotel located near New Mexico State University. Provides 3 bars, an outdoor pool and a 24-hour fitness centre. La Quinta Inn & Suites by Wyndham Las Cruces Organ Mountain and Days Inn by Wyndham Las Cruces are two additional hotels that offer an on-site pool. View all hotels with pools in Mesilla.
What is staying in Mesilla like?
Visitors can enjoy all that Mesilla has to offer, including the restaurants, shopping and theatres. In Mesilla, there are 14 hotels and other accommodation options to choose from. Find out more about Mesilla.
What should I do while I'm visiting Mesilla?
Cultural venues include Fountain Theatre and Fountain Theater. Landmarks like Mesillia Plaza and San Albino Basilica might be worth a visit. Additionally, you might want to add Rio Grande to your itinerary. Take a look at what more there is to see and do in Expedia's Mesilla guide.
What's the seasonal weather in Mesilla?
The hottest months are usually June and July, with an average temperature of 28°C, while the coldest months are January and December, with an average of 9°C. Average annual precipitation for Mesilla is 227 mm.