St. Louis Hotel Guide. Hotels in Midtown, St. Louis, United States of America

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Check prices for these dates

Tonight
14 Nov - 15 Nov
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15 Nov - 16 Nov
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20 Nov - 22 Nov
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27 Nov - 29 Nov

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Our top choices for Midtown hotels

A modern bar area with a long counter, bar stools, and a variety of bottles.

1. Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown
8.8 out of 10, Excellent, (860 reviews)
"Would stay again!"
United States
Julie
The price is €142
includes taxes & fees
29 Nov - 30 Nov
Element by Marriott St. Louis Midtown
A cozy living room with a fireplace, large windows, and a bar area.

2. Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.6 out of 10, Good, (1,000 reviews)
"The room was very clean, with no normal hotel mildew smell. The lack of smell was amazing, actually. The staff was super helpful and parking was gated with plenty of spots. We’d definitely be back! Thank you Marriot."
United States
Kirsten
The price is €119
includes taxes & fees
22 Nov - 23 Nov
Residence Inn by Marriott St Louis Downtown
A rooftop terrace with outdoor seating, string lights, and a city skyline view.

3. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
0.8 km from Midtown
8.8 out of 10, Excellent, (1,173 reviews)
"Loved the hotel!"
United States
Stephanie
The price is €110
includes taxes & fees
25 Nov - 26 Nov
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
An indoor pool area with a hot tub, seating, and a stone wall.

4. Drury Plaza Hotel St. Louis Union Station

Drury Plaza Hotel St. Louis Union Station
3.0 star property
Downtown West, 1.5 km from Midtown
9.4 out of 10, Exceptional, (1,624 reviews)
"Love staying here"
United States
gina
The price is €122
includes taxes & fees
22 Nov - 23 Nov
Drury Plaza Hotel St. Louis Union Station
A modern living room with a fireplace, a large forest-themed painting, and a cozy seating area with a sofa and a coffee table.

5. Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
Downtown West, 1.3 km from Midtown
9.2 out of 10, Wonderful, (1,001 reviews)
"I would stay here again."
United States
Demarco
The price is €119
includes taxes & fees
22 Nov - 23 Nov
Fairfield Inn & Suites by Marriott St. Louis Downtown
Property amenity

6. Pear Tree Inn St. Louis Near Union Station

Pear Tree Inn St. Louis Near Union Station
3.0 star property
Downtown West, 1.2 km from Midtown
8.8 out of 10, Excellent, (2,285 reviews)
"It was nice place to stay and the staff was great."
United States
Samuwel
The price is €110
includes taxes & fees
22 Nov - 23 Nov
Pear Tree Inn St. Louis Near Union Station
A modern hotel entrance with a covered walkway, a landscaped garden, and a clear sky.

7. Courtyard by Marriott St. Louis Downtown West

Courtyard by Marriott St. Louis Downtown West
3.0 star property
Downtown West, 1.1 km from Midtown
8.6 out of 10, Excellent, (1,003 reviews)
"We had a wonderful stay"
Canada
nadia
The price is €123
includes taxes & fees
15 Dec - 16 Dec
Courtyard by Marriott St. Louis Downtown West
A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

8. The West End

The West End
2.0 star property
Central West End, 2.2 km from Midtown
8.6 out of 10, Excellent, (716 reviews)
"Super Nice staff and the room was clean"
United States
Adam
The price is €92
includes taxes & fees
15 Nov - 16 Nov
The West End
A modern kitchen with a hexagonal tile backsplash, built-in appliances, and a central island.

9. Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 2.5 km from Midtown
7.8 out of 10, Good, (1,002 reviews)
"Its a nice hotel with good breakfast"
United States
Arthur
The price is €78
includes taxes & fees
11 Dec - 12 Dec
Tru By Hilton St. Louis Downtown
A Comfort Inn & Suites hotel with a covered entrance, brick facade, and a parking lot.

10. Comfort Inn & Suites Saint Louis Lafayette Square

Comfort Inn & Suites Saint Louis Lafayette Square
2.5 star property
The Gate, 2 km from Midtown
8.2 out of 10, Very good, (438 reviews)
"I love the Comfort inn. So clean, so comfortable and staff is always nice."
United States
Michelle
The price is €115
includes taxes & fees
6 Dec - 7 Dec
Comfort Inn & Suites Saint Louis Lafayette Square
An outdoor dining area with a glass table and chairs, a neon sign, and a city view.

11. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 2.2 km from Midtown
8.6 out of 10, Excellent, (1,001 reviews)
"Very nice staff and helped us with all our needs and was close to the event we were going to and loved the pool table and pool they had there"
United States
Brittany
The price is €121
includes taxes & fees
26 Nov - 27 Nov
Aloft by Marriott St Louis Central West End
Bar (on property)

12. 21C Museum Hotel St Louis

21C Museum Hotel St Louis
4.5 star property
Downtown West, 2.1 km from Midtown
9.0 out of 10, Wonderful, (2,129 reviews)
"Wonderful Stay!"
United States
A.R.
The price is €157
includes taxes & fees
6 Dec - 7 Dec
21C Museum Hotel St Louis
A spacious lobby with ornate ceiling designs, a bar area with stools, and a seating area with tables.

13. St. Louis Union Station Hotel, Curio Collection by Hilton

St. Louis Union Station Hotel, Curio Collection by Hilton
4.0 star property
Downtown West, 1.7 km from Midtown
8.8 out of 10, Excellent, (1,003 reviews)
"Front desk staff was very helpful in answering question about the property and surrounding area!"
United States
William
The price is €167
includes taxes & fees
22 Nov - 23 Nov
St. Louis Union Station Hotel, Curio Collection by Hilton
A multi-story building with a classic architectural style, featuring numerous windows and a brick facade.

14. Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 2.9 km from Midtown
9.0 out of 10, Wonderful, (1,000 reviews)
"Good for a quick stay a little pricey for what you get"
United States
Jackson
The price is €104
includes taxes & fees
22 Nov - 23 Nov
Courtyard by Marriott St. Louis Downtown/Convention Center
A modern hotel with a central entrance, large windows, and a brick facade.

15. AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 3.4 km from Midtown
9.0 out of 10, Wonderful, (863 reviews)
"Everything at this hotel was perfect. From the valet to the front desk to the breakfast were so friendly and nice. We will definitely stay here again. The location is also perfect"
United States
Janice
The price is €153
includes taxes & fees
26 Nov - 27 Nov
AC Hotel St. Louis Central West End
A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

16. Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 3.1 km from Midtown
9.0 out of 10, Wonderful, (1,368 reviews)
"Loved our stay!"
United States
Megan
The price is €114
includes taxes & fees
10 Dec - 11 Dec
Embassy Suites by Hilton St. Louis Downtown
A modern interior with hanging chairs and ottomans, large windows with a view of the street.

17. Home2 Suites by Hilton St. Louis Downtown

Home2 Suites by Hilton St. Louis Downtown
3.0 star property
Downtown West, 2.5 km from Midtown
8.0 out of 10, Very good, (1,002 reviews)
"The staff was very pleasant, and we enjoyed everything"
United States
blanca
The price is €107
includes taxes & fees
22 Nov - 23 Nov
Home2 Suites by Hilton St. Louis Downtown
An outdoor dining area with multiple wooden tables and benches, surrounded by wicker chairs.

18. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 3.2 km from Midtown
8.8 out of 10, Excellent, (1,001 reviews)
"Great place, bar and food was excellent. Would definitely stay here again."
United States
Gordon
The price is €134
includes taxes & fees
13 Dec - 14 Dec
Hotel Indigo St Louis - Central West End by IHG
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

19. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 3 km from Midtown
9.4 out of 10, Exceptional, (1,364 reviews)
"Great place to stay."
United States
brandon
The price is €150
includes taxes & fees
15 Nov - 16 Nov
Live by Loews - St.Louis
A rooftop terrace with wicker chairs and a glass balustrade overlooking a bridge.

20. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 3.4 km from Midtown
9.6 out of 10, Exceptional, (3,841 reviews)
"Very nice hotel.. love that are arch is right behind it.."
United States
Nicole
The price is €143
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel St. Louis at the Arch
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in Midtown

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern bar area with a long counter, bar stools, and a variety of bottles.
Element by Marriott St. Louis Midtown
3.0 star property
8.8
Excellent
860 reviews
View
A cozy living room with a fireplace, large windows, and a bar area.
Residence Inn by Marriott St Louis Downtown
3.0 star property
7.6
Good
1,000 reviews
View
An indoor pool area with a hot tub, seating, and a stone wall.
Drury Plaza Hotel St. Louis Union Station
3.0 star property
9.4
Exceptional
1,624 reviews
View
A rooftop terrace with outdoor seating, string lights, and a city skyline view.
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
8.8
Excellent
1,173 reviews
View
A modern living room with a fireplace, a large forest-themed painting, and a cozy seating area with a sofa and a coffee table.
Fairfield Inn & Suites by Marriott St. Louis Downtown
3.0 star property
9.2
Wonderful
1,001 reviews
View

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.
The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Old Courthouse to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

A historic building with a green dome and adjacent modern high-rise buildings.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

Frequently Asked Questions

What is Midtown like?

Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.

Where is the best place to stay in Midtown?

Based on our traveller data, Element by Marriott St. Louis Midtown is one of the top choices for your stay in Midtown. This hotel is a short 6-minute walk from St. Louis University, and it offers free breakfast and an indoor pool.

How many hotels will I be able to find in the Midtown area?

If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 36 Midtown hotels and other accommodation options to choose from.

If I need to cancel my hotel reservation in Midtown, will I receive a refund?

Yes! Most hotel room reservations are refundable if you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.

What are the top things to see and do in Midtown?

Sights like Red Flag, Scott Joplin House State Historic Site and Museum of Contemporary Religious Art can be part of your cultural tour of Midtown. Chaifetz Arena and Washington Avenue Historic District are also a couple of places to visit in the neighbourhood. St. Louis Union Station, Hermann Stadium and .ZACK Theater are just a few of the places to visit in and around Midtown. While you're out sightseeing, Fubar and The Sovereign - St. Louis are a couple of additional sights to visit in St. Louis.

How can I get around Midtown and the greater St. Louis area?

Ready to get out and explore the city? Grand Station is the closest metro station.