St. Louis Hotel Guide. Hotels in Midtown, St. Louis, United States of America

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23 Dec - 24 Dec
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24 Dec - 25 Dec
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26 Dec - 28 Dec
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Our top choices for Midtown hotels

BBQ/picnic Area
Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown

Residence Inn by Marriott St Louis Downtown
3.0 star property
Midtown
7.8 out of 10, Good, (1002)
"Room was as expected. "
United States
Ruth
The price is €111
includes taxes & fees
27 Dec - 28 Dec
Residence Inn by Marriott St Louis Downtown
Courtyard
Element St. Louis Midtown

Element St. Louis Midtown

Element St. Louis Midtown
3.0 star property
Midtown
9.0 out of 10, Wonderful, (647)
"Everything was excellent. The staff were very friendly and helpful. The accommodations were excellent and it was a great location near every where we were going."
United States
Angela
The price is €130
includes taxes & fees
30 Dec - 31 Dec
Element St. Louis Midtown
Lobby
Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO

Motel 6 Hazelwood, MO
2.0 star property
21 km from Midtown
8.4 out of 10, Very good, (1636)
"Great stay!"
United States
Ambrose
The price is €62
includes taxes & fees
11 Jan - 12 Jan 2026
Motel 6 Hazelwood, MO
Lobby
Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia

Hampton Inn St. Louis - Columbia
2.5 star property
21.2 km from Midtown
8.6 out of 10, Excellent, (476)
"Breakfast was great and a very good atten"
United States
John
The price is €92
includes taxes & fees
18 Jan - 19 Jan 2026
Hampton Inn St. Louis - Columbia
Breakfast, dinner and brunch served
The Principal Hotel

The Principal Hotel

The Principal Hotel
3.5 star property
21.3 km from Midtown
9.8 out of 10, Exceptional, (193)
"Great place. Very nice rooms, new and clean."
United States
Jeff
The price is €106
includes taxes & fees
24 Dec - 25 Dec
The Principal Hotel
Indoor pool
Casino Queen Hotel

Casino Queen Hotel

Casino Queen Hotel
3.0 star property
4.5 km from Midtown
7.6 out of 10, Good, (1979)
"Clean and comfortable room, pleasant staff."
United States
Bradley
The price is €83
includes taxes & fees
24 Dec - 25 Dec
Casino Queen Hotel
Indoor pool
Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station

Drury Inn & Suites St. Louis Union Station
3.0 star property
Downtown West, 1.5 km from Midtown
9.4 out of 10, Exceptional, (1304)
"Very clean room and staff was very nice."
United States
Carlos
The price is €120
includes taxes & fees
30 Dec - 31 Dec
Drury Inn & Suites St. Louis Union Station
Lobby
Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport

Fairfield Inn & Suites St Louis Westport
2.5 star property
20 km from Midtown
9.2 out of 10, Wonderful, (811)
"Everything was great "
United States
Alan
The price is €121
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites St Louis Westport
Exterior
Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown
4.0 star property
Downtown St. Louis, 3.1 km from Midtown
8.8 out of 10, Excellent, (1248)
"The room was spacious, and breakfast was very good with great coffee."
United States
Susan
The price is €111
includes taxes & fees
29 Dec - 30 Dec
Embassy Suites by Hilton St. Louis Downtown
Lobby
SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood

SpringHill Suites St. Louis Brentwood
3.0 star property
9.5 km from Midtown
9.0 out of 10, Wonderful, (1001)
"Really liked the room--very spacious with a lot of room to spread out. Excellent breakfast! Note that parking is $10/night. I missed that when looking for a St. Louis hotel. "
United States
Leslie
The price is €112
includes taxes & fees
21 Jan - 22 Jan 2026
SpringHill Suites St. Louis Brentwood
Exterior
Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG

Holiday Inn Express & Suites Edwardsville by IHG
2.5 star property
27.8 km from Midtown
9.2 out of 10, Wonderful, (821)
"Always a good stay here!"
United States
Chelsie
The price is €113
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Edwardsville by IHG
Indoor pool, open 6:00 AM to 9:00 PM, pool loungers
Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG

Crowne Plaza St. Louis Airport by IHG
3.5 star property
19.1 km from Midtown
8.0 out of 10, Very good, (1005)
"It smelled clean and the staff is wonderful"
United States
Dorothy
The price is €126
includes taxes & fees
22 Jan - 23 Jan 2026
Crowne Plaza St. Louis Airport by IHG
Lobby
Comfort Inn St. Louis Airport

Comfort Inn St. Louis Airport

Comfort Inn St. Louis Airport
3.0 star property
19.2 km from Midtown
8.4 out of 10, Very good, (939)
"Extremely clean hotel! Very friendly staff. Enjoyed my 15 days there."
United States
Warnetta
The price is €85
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Inn St. Louis Airport
Front of property
Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch

Hilton Pennywell St. Louis at the Arch
4.0 star property
Downtown St. Louis, 3.4 km from Midtown
8.8 out of 10, Excellent, (1018)
"My second time staying there as always it was lovely "
United States
Nina
The price is €103
includes taxes & fees
29 Dec - 30 Dec
Hilton Pennywell St. Louis at the Arch
Gazebo
Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis

Country Hearth Inn & Suites Edwardsville St. Louis
2.5 star property
27.6 km from Midtown
8.6 out of 10, Excellent, (649)
"The room was very clean and the staff is always friendly "
United States
Lynn
The price is €89
includes taxes & fees
1 Jan - 2 Jan 2026
Country Hearth Inn & Suites Edwardsville St. Louis
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 3 km from Midtown
8.8 out of 10, Excellent, (1168)
"Staff was helpful at suggesting places to eat and shop"
United States
Ann Marie
The price is €81
includes taxes & fees
26 Dec - 27 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis

Comfort Inn Edwardsville - St. Louis
2.5 star property
24.2 km from Midtown
8.4 out of 10, Very good, (808)
"Great staff, breakfast was excellent and rooms were clean"
United States
Carlos
The price is €96
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn Edwardsville - St. Louis
Lobby
Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 3.3 km from Midtown
9.0 out of 10, Wonderful, (1056)
"It was perfect for our stay in St. Louis to visit the arch."
United States
Jacob
The price is €93
includes taxes & fees
27 Dec - 28 Dec
Pear Tree Inn St. Louis Convention Center
Exterior
Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center

Courtyard by Marriott St. Louis Downtown/Convention Center
3.0 star property
Downtown St. Louis, 2.9 km from Midtown
9.0 out of 10, Wonderful, (1003)
"Was a great stay. "
United States
Lorilyn
The price is €98
includes taxes & fees
20 Jan - 21 Jan 2026
Courtyard by Marriott St. Louis Downtown/Convention Center
Free daily buffet breakfast
SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City

SpringHill Suites by Marriott St. Louis Airport/Earth City
3.0 star property
23.5 km from Midtown
8.8 out of 10, Excellent, (1002)
"Location wasn’t the greatest but the room was awesome. "
United States
Shawn
The price is €105
includes taxes & fees
5 Jan - 6 Jan 2026
SpringHill Suites by Marriott St. Louis Airport/Earth City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Busch Stadium to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Midtown Hotel Reviews

Embassy Suites by Hilton St. Louis Downtown

Embassy Suites by Hilton St. Louis Downtown

10/10 Excellent
"The room was spacious, and breakfast was very good with great coffee."
Susan 1-night trip
Posted 18 hours ago
Embassy Suites by Hilton St. Louis Downtown

Frequently asked questions

What is Midtown like?
Travellers are sure to enjoy a stay in St. Louis's Midtown neighbourhood. Make sure that you visit Chaifetz Arena and Washington Avenue Historic District as part of your Midtown travel plans.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, Element St. Louis Midtown is the highest ranked property in Midtown. This hotel offers free breakfast and an indoor pool. Another top choice in the area is Residence Inn by Marriott St Louis Downtown.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in St. Louis, Expedia has something to meet your needs with 30 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes! Most hotel room reservations are refundable if you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you have a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to get top deals in Midtown.
What are the top things to see and do in Midtown?
Explore Midtown's landmarks such as Washington Avenue Historic District, Samuel Cupples House and Scott Joplin House State Historic Site and learn about the local history. Chaifetz Arena and Topgolf are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Gateway Arch are some popular places to visit in the area around Midtown. While you're out sightseeing, .ZACK Theater and The MOTO Museum are a couple of additional sights to visit in St. Louis.
How can I get around Midtown and the greater St. Louis area?
Ready to get out and explore the city? Grand Station is the closest metro station.