Mission Bay Holidays

Photo by Rebecca Friedland

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    Save up to €185 when you book a flight and hotel together*

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Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
Union Square which includes a skyscraper and a city

Union Square

4/5(287 area reviews)

This famous shopping area is a magnet for fashionistas as well as a historic landmark of old San Francisco.

Find hotels in Union Square

Top hotels in Mission Bay

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is €195 per night from 28 Dec to 29 Dec
€195
28 Dec - 29 Dec
includes taxes & fees
9.4/10 Exceptional! (2,389 reviews)
Corner King Room had amazing views and very spacious. Rooftop restaurant was fun & the location of hotel was perfect

Reviewed on 20 Dec 2025

LUMA Hotel San Francisco
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is €138 per night from 5 Jan to 6 Jan
€138
5 Jan - 6 Jan 2026
includes taxes & fees
8.8/10 Excellent! (7,226 reviews)
Very nice lobby. Very clean throughout. Nice decor.Employee handing out review cards on Tuesday morning in the breakfast room was not very nice. Everything else was great!

Reviewed on 23 Dec 2025

Hotel Riu Plaza Fisherman's Wharf
Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is €110 per night from 4 Jan to 5 Jan
€110
4 Jan - 5 Jan 2026
includes taxes & fees
8.6/10 Excellent! (2,156 reviews)
Everything was as expected from a nice hotel. Location is great and for San Francisco, easy of parking is a huge plus. The hotel has a bar / restaurant but there is no room service offered (fyi).

Reviewed on 21 Dec 2025

Hilton San Francisco Financial District
See all 4,886 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Bay holiday package cost?
Custom make your Mission Bay holiday package from as low as . Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay holiday package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay holiday?
Smart travellers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organising an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia holiday package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay holiday package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay holiday package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Things to do

Alcatraz Ticket with Roundtrip Ferry & Hop-On Hop-Off

Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour

€103
per adult
88% of travellers recommend
Alcatraz Island Ticket and Hop-on Hop-Off Bus Tour
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

€42
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Go City: San Francisco All-Inclusive Pass with 25+ Attractions

Go City: San Francisco All-Inclusive Pass with 30+ Attractions

€89
per adult
88% of travellers recommend
Go City: San Francisco All-Inclusive Pass with 30+ Attractions
See all activities in San Francisco
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.