
New Madrid Holidays
- Plan, book, travel with confidence
- Better togetherSave up to €900 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top hotels in New Madrid

Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!
New Madrid MO
Fully refundable
The price is €319 per night from 10 Nov to 11 Nov
€319
10 Nov - 11 Nov
includes taxes & fees
10/10 Exceptional! (1 review)
"The host was very quick to respond and so great to work with for on our stay."
Reviewed on 11 Nov 2025

Hampton Inn Sikeston
1240 Commerce Drive Sikeston MO
Fully refundableReserve now, pay when you stay
The price is €102 per night from 22 Nov to 23 Nov
€102
22 Nov - 23 Nov
includes taxes & fees

Holiday Inn Express & Suites Sikeston Southwest by IHG
115 Hospitality Dr Sikeston MO
Fully refundable
The price is €103 per night from 15 Nov to 16 Nov
€103
15 Nov - 16 Nov
includes taxes & fees
8.8/10 Excellent! (522 reviews)
"N:A"
Reviewed on 6 Nov 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular New Madrid attractions
Frequently asked questions
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
