New Madrid Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
5 Jun - 7 Jun
In two weeks
12 Jun - 14 Jun

Filter by

Guest rating
Guest rating
Star rating

Our top choices for New Madrid hotels

Room, 1 Queen Bed, Non Smoking

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
8.0 out of 10, Very good, (64 reviews)
"Great hotel for the price!!! Remodel very nice and modern. "
United States
Amy
The price is €74
includes taxes & fees
31 May - 1 Jun
Super 8 By Wyndham Marston
Property amenity

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (84 reviews)
"The breakfast was good, the service was good, and the staff was very friendly"
United States
Angela
The price is €107
includes taxes & fees
7 Jun - 8 Jun
Fairfield Inn & Suites by Marriott Sikeston
Standard Room, 2 Double Beds, Non Smoking

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (493 reviews)
"The lake view was beautiful and staff was amazing"
United States
Richard
The price is €69
includes taxes & fees
3 Jun - 4 Jun
Reelfoot Lake Inn
Exterior

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (569 reviews)
"Very clean hotel with comfortable bedding. Front desk staff was very nice and accommodating as we were traveling with a small dog."
United States
Connie
The price is €102
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn Sikeston
Property amenity

TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston
3.0 star property
Sikeston
9.2 out of 10, Wonderful, (18 reviews)
"Room was very nice and in very clean condition and hotel staff was very helpful and polite. The breakfast was very delicious and coffee served all day. The hotel smelled very nice and had a very welcoming feeling. Will definitely book with them again"
United States
Joseph
The price is €123
includes taxes & fees
7 Jun - 8 Jun
TownePlace Suites by Marriott Sikeston
Desk, free WiFi, bed sheets

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O
2.5 star property
Marston
6.0 out of 10, (124 reviews)
"The room was great, TV was awesome. Staff was friendly."
United States
Stanley
The price is €47
includes taxes & fees
29 Jun - 30 Jun
Travel Inn Marston I-55 by Hotel O
Exterior

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (466 reviews)
"Only stayed one night, no complaints"
United States
Zachary
The price is €102
includes taxes & fees
21 Jun - 22 Jun
Holiday Inn Express & Suites Sikeston Southwest by IHG
Premier Room, 1 Bedroom, Non Smoking

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very good, (766 reviews)
"Parking was right outside my window so as safe as can be. The staff on the other hand are extremely helpful and wonderful to talk to. Very friendly and professional. "
United States
Honorio
The price is €53
includes taxes & fees
28 Jun - 29 Jun
New Orleans Inn Portageville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular New Madrid attractions

River Ridge Winery

4.2/5 (15 reviews)
Sip handcrafted wines in a century-old farmhouse atop the Mississippi River hills. Wander through estate vineyards or enjoy fresh meals on the scenic grounds of this Missouri wine destination.
See properties

Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic storey of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

See all hotels in New Madrid
Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. .

Top New Madrid Hotel Reviews

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

10/10 Excellent
"Great stay, kind staff, very clean property."
Joni 1-night trip
Posted 7 hours ago
Fairfield Inn & Suites by Marriott Sikeston

More cheap stays in New Madrid

Travel Inn Marston I-55 by Hotel O

Travel Inn Marston I-55 by Hotel O

301 Route Ad Marston MO
The price is €47 per night from 29 Jun to 30 Jun
€47
29 Jun - 30 Jun
includes taxes & fees
6/10 (124 reviews)

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 18.9 mi (30.4 km) from the heart of New Madrid, is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Reelfoot Lake Inn and Fairfield Inn & Suites by Marriott Sikeston. See all available top hotels, or vacation rentals in New Madrid.
What are some of the best holiday rentals that New Madrid has to offer?
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!: This highly rated holiday home rental in New Madrid offers a garden, a selection of games and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer, including the parks and museums. There are 58 hotels and other accommodation options in the surrounding area. Find out more about New Madrid.
What should I do while I'm visiting New Madrid?
Cultural venues include Hunter-Dawson State Historic Site and New Madrid Historical Museum. A couple of additional sights to add to your itinerary are River Ridge Winery and Mississippi River. Take a look at what more there is to see and do in Expedia's New Madrid guide.
What's the seasonal weather in New Madrid?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 6°C. Average annual precipitation for New Madrid is 1537 mm.

Explore a world of travel with Expedia