New Madrid Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
28 Nov - 29 Nov
Tomorrow
29 Nov - 30 Nov
This weekend
28 Nov - 30 Nov
Next weekend
5 Dec - 7 Dec

Filter by

Guest rating
Guest rating
Star rating

Top 10 trending New Madrid hotels

Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (436)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is €93
includes taxes & fees
7 Dec - 8 Dec
Hampton Inn Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

2.5 star property
Sikeston
8.6 out of 10, Excellent, (440)
"Clean and nice facilities. All the staff we met were friendly and helpful. Breakfast was great."
United States
Kristen
The price is €93
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express & Suites Sikeston Southwest by IHG
Exterior
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

2.0 star property
Marston
7.8 out of 10, Good, (37)
"Todo excelente "
Mexico
Lirra Diaz
The price is €52
includes taxes & fees
29 Nov - 30 Nov
Super 8 By Wyndham Marston
Premier Room, 1 Bedroom, Non Smoking
New Orleans Inn Portageville

New Orleans Inn Portageville

2.5 star property
Portageville
8.0 out of 10, Very good, (723)
"Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling."
United States
Roger
New Orleans Inn Portageville
Bar (on property)
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

2.5 star property
Sikeston
9.2 out of 10, Wonderful, (37)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is €99
includes taxes & fees
4 Dec - 5 Dec
Fairfield Inn & Suites by Marriott Sikeston
Bar (on property)
TownePlace Suites by Marriott Sikeston

TownePlace Suites by Marriott Sikeston

3.0 star property
Sikeston
9.0 out of 10, Wonderful, (7)
"Great hotel! Very clean, quiet, plenty of amenities, pool was clean, breakfast in the morning was good with lots of options. I would definitely stay here again. "
United States
Scott
The price is €111
includes taxes & fees
25 Dec - 26 Dec
TownePlace Suites by Marriott Sikeston
Gazebo
Travel Inn

Travel Inn

2.5 star property
Marston
6.0 out of 10, (116)
"Had a great time loved it "
United States
Shyianne
Travel Inn
Handicap Room
Reelfoot Lake Inn

Reelfoot Lake Inn

2.0 star property
Tiptonville
7.2 out of 10, Good, (457)
"Nice and quiet but there were bugs in the room the fridge didn't keep things cold and the A/C didn't keep the room cool. Great place if you're a fisherman."
United States
Carla
The price is €69
includes taxes & fees
29 Nov - 30 Nov
Reelfoot Lake Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular New Madrid attractions

New Madrid Historical Museum

4.1/5 (17 reviews)
You can study the exhibits at New Madrid Historical Museum, a museum with a storied past, during your travels to New Madrid. Amble around the area's parks or experience its museums.
See properties

River Ridge Winery

3.9/5 (10 reviews)
You can enjoy a tasting or tour at River Ridge Winery during your travels to New Madrid. Amble around the area's parks or experience its museums.
See properties

Learn more about New Madrid

The New Madrid Historical Museum reveals the dramatic storey of the 1811-1812 earthquakes that changed the course of the Mississippi River. Enjoy peaceful fishing at Donaldson Point Conservation Area or take a sunset river cruise to spot bald eagles along the mighty Mississippi.

See all hotels in New Madrid
Mississippi River Walk at New Madrid. A magnificent view of the Mississippi river from atop of the levee. A steamboat is docked down river. .

Top New Madrid Hotel Reviews

Travel Inn

Travel Inn

10/10 Excellent
"This motel is on a side road by open fields next to the expressway. The parking lot is large and well lit at night. It felt like a reasonably safe place. The desk clerk was friendly and helpful. The room was clean but a little worse for wear in some ways. The bed was comfortable and the HVAC unit worked well. Breakfast was just coffee, cold cereal and milk. "
Keith 1-night trip
Posted 5 days ago
Travel Inn

More cheap stays in New Madrid

Hampton Inn Sikeston

Hampton Inn Sikeston

1240 Commerce Drive Sikeston MO
The price is €93 per night from 7 Dec to 8 Dec
€93
7 Dec - 8 Dec
includes taxes & fees
8.8/10 Excellent! (429 reviews)

Frequently asked questions

Where is the best place for a stay in New Madrid?
Hampton Inn Sikeston, located 19 mi (30.5 km) from the heart of New Madrid, is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Fairfield Inn & Suites by Marriott Sikeston and For Larger Groups Up To 24, Right on Reelfoot Lake--Private Dock And Pier.. See all available top hotels, or vacation rentals in New Madrid.
What are some of the best holiday rentals that New Madrid has to offer?
Spacious 3-bedroom 2 story house in New Madrid near boat ramp with a toy room!: This highly rated holiday home rental in New Madrid offers a garden, a selection of games and air conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a dishwasher, a fridge and a stovetop. See all vacation rentals in New Madrid.
If I need to cancel my hotel reservation in New Madrid, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, it might still be possible to cancel it and be given a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in New Madrid.
What is staying in New Madrid like?
Visitors can enjoy all that New Madrid has to offer, including the parks and museums. There are 52 hotels and other accommodation options in the surrounding area. Find out more about New Madrid.
What should I do while I'm visiting New Madrid?
Cultural venues include New Madrid Historical Museum and Hunter-Dawson State Historic Site. A couple of additional sights to add to your itinerary are River Ridge Winery and Mississippi River. Take a look at what more there is to see and do in Expedia's New Madrid guide.
What's the seasonal weather in New Madrid?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 6°C. Average annual precipitation for New Madrid is 1537 mm.

Explore a world of travel with Expedia