Puxico Holidays
Photo by Mike McClain
- Plan, book, travel with confidence
- Better togetherSave up to €900 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Top hotels in Puxico
Hampton Inn Poplar Bluff
2420 Crestwood Dr Poplar Bluff MO
Fully refundableReserve now, pay when you stay
The price is €89 per night from 17 May to 18 May
€89
17 May - 18 May
includes taxes & fees
9.4/10 Exceptional! (829 reviews)
We had an excellent stay! Very clean and super friendly staff!
Reviewed on 1 May 2026
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
Fully refundableReserve now, pay when you stay
The price is €62 per night from 4 May to 5 May
€62
4 May - 5 May
includes taxes & fees
8/10 Very Good! (1,000 reviews)
Floors and windows in room were dirty.. terrible lighting TERRIBLE!!!
Reviewed on 27 Apr 2026
Drury Inn & Suites Poplar Bluff
2220 N Westwood Blvd Poplar Bluff MO
Fully refundableReserve now, pay when you stay
The price is €96 per night from 17 May to 18 May
€96
17 May - 18 May
includes taxes & fees
9.2/10 Wonderful! (1,001 reviews)
The room was clean. The bed was very comfortable.
Reviewed on 2 May 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Explore a world of travel with Expedia
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
