Puxico Hotels

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
In two weeks

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Puxico hotels

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,000 reviews)
"Overall stay was convenient."
United States
Salman Mahmud
The price is €62
includes taxes & fees
11 May - 12 May
Motel 6 Poplar Bluff, MO

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (893 reviews)
"Staff is Great , Room very clean and well stocked ."
United States
joan
The price is €106
includes taxes & fees
6 May - 7 May
Fairfield Inn & Suites by Marriott Poplar Bluff

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (829 reviews)
"The breakfast was great."
United States
Carolyn
The price is €89
includes taxes & fees
17 May - 18 May
Hampton Inn Poplar Bluff

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (344 reviews)
"Nice rooms, friendly staff, "
United States
Sarah
The price is €57
includes taxes & fees
3 May - 4 May
Dexter Inn

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (89 reviews)
"Great place to stay! Nostalgic dining connected to hotel is pretty cool. If nearby, for sure stay with them."
United States
Jacob
The price is €87
includes taxes & fees
3 May - 4 May
EC Reed's Mercantile and Hotel

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,000 reviews)
"Clean, comfortable room and great staff!"
United States
Kendra
The price is €96
includes taxes & fees
17 May - 18 May
Drury Inn & Suites Poplar Bluff

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (737 reviews)
"Wonderful restaurant and rooms "
United States
Robert
The price is €86
includes taxes & fees
23 May - 24 May
Holiday Inn Poplar Bluff by IHG

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (402 reviews)
"Clean room, staff was super helpful"
United States
Katherine
The price is €83
includes taxes & fees
11 May - 12 May
Travelodge by Wyndham Dexter

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (641 reviews)
"Yes pet friendly "
United States
Dave
The price is €53
includes taxes & fees
10 May - 11 May
Super 8 by Wyndham Poplar Bluff Missouri

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (260 reviews)
"The stay was very nice. Animal friendly, staff is super nice and house keeping is very respectful. I appreciate everyone. "
United States
Michelle
The price is €49
includes taxes & fees
2 Jun - 3 Jun
Econo Lodge Dexter

Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (410 reviews)
"Positives: Lobby was immaculate, the desk staff was very friendly overly accommodating as well as the people who handled the breakfast. 👌 Negative: this place needs a whole lot of fixture updates room doors, faucets, exhaust fans ect."
United States
JOHN
The price is €87
includes taxes & fees
28 May - 29 May
Comfort Inn Poplar Bluff North

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
10.0 out of 10, Exceptional, (22 reviews)
"Great stay "
United States
Ashley
The price is €86
includes taxes & fees
17 May - 18 May
Hampton Inn By Hilton Dexter

Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
10.0 out of 10, Exceptional, (2 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is €76
includes taxes & fees
6 May - 7 May
Lake Wappapello

OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (138 reviews)
"We enjoyed every moment of our stay. Wonderful service—everyone was friendly and helpful."
United States
Albert
The price is €52
includes taxes & fees
17 May - 18 May
OYO Hickory House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

Photo by Mike McClain
Open Photo by Mike McClain

Top Puxico Hotel Reviews

More cheap stays in Puxico

Frequently asked questions

What's the best place for a stay in Puxico?
Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Hampton Inn Poplar Bluff and Holiday Inn Poplar Bluff by IHG. See all available top hotels, or vacation rentals in Puxico.
What are some of the best holiday rentals that Puxico has to offer?
Private lake, beach & hot tub, romantic getaway or family vaca: This holiday home rental outside of Puxico is equipped with 1 hot tub, air conditioning and laundry facilities to help you feel comfortable during your stay. See all vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
What is staying in Puxico like?
Travellers to Puxico will find plenty to explore and enjoy. There are 56 hotels and other accommodation options in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.
What's the seasonal weather in Puxico?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

Explore a world of travel with Expedia