Puxico Hotels

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Check prices for these dates

This weekend
19 Jun - 21 Jun
Next weekend
26 Jun - 28 Jun

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Guest rating

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Star rating

Our top choices for Puxico hotels

Free daily buffet breakfast

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (875 reviews)
"Nice quiet overnight stay."
United States
Tammy
The price is €96
includes taxes & fees
9 Jul - 10 Jul
Hampton Inn Poplar Bluff
Lobby

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (920 reviews)
"Hotel Staff was very friendly!"
United States
Alice
The price is €108
includes taxes & fees
15 Jul - 16 Jul
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,001 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
United States
Stephanie
The price is €108
includes taxes & fees
28 Jun - 29 Jun
Drury Inn & Suites Poplar Bluff
Lobby sitting area

EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
3.0 star property
Marble Hill
9.6 out of 10, Exceptional, (100 reviews)
"It was a very neat experience! Highly recommend you stop here and get away from big chain hotels for a night. The staff were super friendly and the restaurant/store was so nostalgic!"
United States
DANIELLE
The price is €98
includes taxes & fees
21 Jun - 22 Jun
EC Reed's Mercantile and Hotel
Lobby

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
2.5 star property
Dexter
9.8 out of 10, Exceptional, (39 reviews)
"Great place to stay"
United States
Lauren
The price is €107
includes taxes & fees
12 Jul - 13 Jul
Hampton Inn By Hilton Dexter
Coffee service

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
Poplar Bluff
8.0 out of 10, Very good, (1,001 reviews)
"Clean room and convenient location."
United States
Morgan
The price is €73
includes taxes & fees
22 Jun - 23 Jun
Motel 6 Poplar Bluff, MO
Breakfast, lunch and dinner served

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (746 reviews)
"Great staff especially Ms Wilma at the front desk!"
United States
Denise
The price is €96
includes taxes & fees
28 Jun - 29 Jun
Holiday Inn Poplar Bluff by IHG
Front of property

Lake Wappapello

Lake Wappapello
2.0 star property
Williamsville
10.0 out of 10, Exceptional, (2 reviews)
"Pet friendly. Family-friendly "
United States
Tonya
The price is €70
includes taxes & fees
24 Jun - 25 Jun
Lake Wappapello
Breakfast area

Dexter Inn

Dexter Inn
2.5 star property
Dexter
7.0 out of 10, Good, (350 reviews)
"Nice rooms, friendly staff, "
United States
Sarah
The price is €64
includes taxes & fees
21 Jun - 22 Jun
Dexter Inn
In-room safe, desk, free WiFi, bed sheets

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
Poplar Bluff
6.6 out of 10, (649 reviews)
"Easy to check in"
United States
Aisa
The price is €59
includes taxes & fees
6 Jul - 7 Jul
Super 8 by Wyndham Poplar Bluff Missouri
Desk, iron/ironing board, free WiFi, bed sheets

Econo Lodge Dexter

Econo Lodge Dexter
2.0 star property
Dexter
6.8 out of 10, (266 reviews)
"Air was not cold, bathroom door did not close, not a good selection for breakfast"
United States
Amanda
The price is €50
includes taxes & fees
20 Jul - 21 Jul
Econo Lodge Dexter
Breakfast, lunch and dinner served

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (410 reviews)
"Clean room, staff was super helpful"
United States
Katherine
The price is €90
includes taxes & fees
21 Jun - 22 Jun
Travelodge by Wyndham Dexter
Lobby

Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
Poplar Bluff
7.8 out of 10, Good, (416 reviews)
"Chad the manager was great getting my family on same floor and close together. The breakfast was very good. Only things negative is needed replace towels in the morning and when clean the room for next person clean under the bed"
United States
jeannie
The price is €95
includes taxes & fees
13 Jul - 14 Jul
Comfort Inn Poplar Bluff North
Desk, iron/ironing board, free WiFi, bed sheets

OYO Hickory House Inn

OYO Hickory House Inn
2.5 star property
Dexter
5.6 out of 10, (139 reviews)
"Loved the room "
United States
Jessica
The price is €54
includes taxes & fees
3 Jul - 4 Jul
OYO Hickory House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico
Photo by Mike McClain
Open Photo by Mike McClain

Top Puxico Hotel Reviews

Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"Very clean. Found several long blond hairs on the entry floor to the room. I’m certain they were trapped by the mop and left unintentionally. Still an excellent rate!"
Lucinda 1-night trip
Posted 6 hours ago
Hampton Inn By Hilton Dexter

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO
The price is €59 per night from 6 Jul to 7 Jul
€59
6 Jul - 7 Jul
includes taxes & fees
6.6/10 (649 reviews)

Frequently asked questions

What's the best place for a stay in Puxico?
Hampton Inn Poplar Bluff, located 18.8 mi (30.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Motel 6 Poplar Bluff, MO and Drury Inn & Suites Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.
What are some of the best holiday rentals that Puxico has to offer?
Dexter Victorian Homestead- Brand NEW Remodel April 2026. VERY Clean & Cozy: This holiday home rental outside of Puxico offers a fireplace, a balcony and a BBQ to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You can relax into your holiday with a garden and a selection of games. See all vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
What is staying in Puxico like?
Travellers to Puxico will find plenty to explore and enjoy. There are 54 hotels and other accommodation options in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.
What's the seasonal weather in Puxico?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

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