A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.

Puxico Hotels

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Check prices for these dates

Tonight
8 Aug - 9 Aug
Tomorrow
9 Aug - 10 Aug
Next weekend
14 Aug - 16 Aug
In two weeks
21 Aug - 23 Aug

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Our top choices for Puxico hotels

Breakfast included
Hotel
Reserve now, pay later
Mingo Wilderness
Pet-friendly

1. Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter
Dexter
United States
Vanessa
€95
includes taxes & fees
16 Aug - 17 Aug
Hampton Inn By Hilton Dexter

2. Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
Poplar Bluff
United States
Elaine
€92
includes taxes & fees
16 Aug - 17 Aug
Drury Inn & Suites Poplar Bluff

3. Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
Poplar Bluff
United States
Philip
€93
includes taxes & fees
6 Sept - 7 Sept
Hampton Inn Poplar Bluff

4. Dexter Inn

Dexter Inn
Dexter
United States
Cynthia
€63
includes taxes & fees
10 Aug - 11 Aug
Dexter Inn

5. Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
Poplar Bluff
United States
Jean
€99
includes taxes & fees
16 Aug - 17 Aug
Fairfield Inn & Suites by Marriott Poplar Bluff

6. Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
Poplar Bluff
United States
Kathleen
€70
includes taxes & fees
10 Aug - 11 Aug
Motel 6 Poplar Bluff, MO

7. Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
Dexter
United States
Steven
€89
includes taxes & fees
16 Aug - 17 Aug
Travelodge by Wyndham Dexter

8. Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
Poplar Bluff
United States
ASHTON
€91
includes taxes & fees
23 Aug - 24 Aug
Holiday Inn Poplar Bluff by IHG

9. Econo Lodge Dexter

Econo Lodge Dexter
Dexter
United States
Herman
€50
includes taxes & fees
7 Sept - 8 Sept
Econo Lodge Dexter

10. Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
Poplar Bluff
United States
Muhammad
€81
includes taxes & fees
30 Aug - 31 Aug
Comfort Inn Poplar Bluff North

11. OYO Hickory House Inn

OYO Hickory House Inn
Dexter
United States
Tammy
€48
includes taxes & fees
22 Aug - 23 Aug
OYO Hickory House Inn

12. Lake Wappapello

Lake Wappapello
Williamsville
United States
Tonya
€70
includes taxes & fees
10 Aug - 11 Aug
Lake Wappapello

13. Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
Poplar Bluff
United States
Diana
€66
includes taxes & fees
22 Aug - 23 Aug
Super 8 by Wyndham Poplar Bluff Missouri

14. EC Reed's Mercantile and Hotel

EC Reed's Mercantile and Hotel
Marble Hill
United States
JANEEN
€79
includes taxes & fees
10 Aug - 11 Aug
EC Reed's Mercantile and Hotel
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Learn more about Puxico

Head to sights like Mark Twain National Forest and Mingo Wilderness as you discover Puxico.

See all hotels in Puxico
A night scene with a clear sky, a crescent moon, and two silhouetted trees against a twilight sky.
Photo by Mike McClain

Top Puxico Hotel Reviews

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

10/10 Excellent
"Excellent stay and Staff!"
Teresa 1-night trip
Posted 9 hours ago
Drury Inn & Suites Poplar Bluff
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

8/10 Good
"F"
Lori 2-night trip
Posted 1 day ago
Comfort Inn Poplar Bluff North
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

10/10 Excellent
"Good hotel. Great breakfast"
Michael 1-night trip
Posted 3 days ago
Holiday Inn Poplar Bluff by IHG
Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

10/10 Excellent
"Great stay helpful people"
Jaden 1-night trip
Posted 5 days ago
Super 8 by Wyndham Poplar Bluff Missouri
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

10/10 Excellent
"During summer time, don’t park behind the building. There’s a pond in the distance and the light draws a TON of mosquitoes there, but the other entrances are all fine. The pond makes for a beautiful view with ducks and cranes, though. Everything about the bed was heavenly. Send the whole thing to my house, pronto! LOL The supplied shower body gel, shampoo, conditioner, and body lotion by Zero% is to die for! Smells great, super moisturizing, and good for the planet? Wow! The free breakfast was awesome! Waffles and fresh oatmeal with a HUGE variety of toppings, cereal and milk, juices, coffees and teas with sweeteners, sugars, creams, and real honey, cocoa, yogurt, boiled eggs, scrambled eggs, bacon, sausage, ranch potatoes, bagels (soft!), muffins, scones, toast and all the spreads for them, fresh fruit… what more could you need FOR FREE? Love love love the packaged reusable/disposable coffee pod holder for the coffee maker in the room. No more worrying if it was cleaned, cleaned properly, or used to wash someone’s underwear beforehand. Water pressure, shower head, and temperature was just right. I wish the light would stay on during the shower, though. And even with the door barely ajar the light and fan was still kicking on when I wasn’t in the bathroom. I was in the bed. Alone. Air conditioner/heater is a vast improvement from the old style in other hotels. It has a wall control just like home! The TV is giant! Anyway, will absolutely be back more than once. Thank you!"
Dawn 1-night trip
Posted 5 days ago
Hampton Inn By Hilton Dexter
Cozy hobby farm cabin under the stars!

Cozy hobby farm cabin under the stars!

10/10 Excellent
"Our second visit"
Anonymous traveller 2-night trip
Posted 6 days ago
Cozy hobby farm cabin under the stars!
OYO Hickory House Inn

OYO Hickory House Inn

10/10 Excellent
"Nice for overnight stop"
Tammy 1-night trip
Posted 10 days ago
OYO Hickory House Inn
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

10/10 Excellent
"The property was very well maintained. Staff was very friendly. Very clean. Only complaint was cleaning ladies threw away a razor my daughter had in shower. It was not a disposable one. They could have just left it where it was."
Aluce 3-night trip
Posted 11 days ago
Hampton Inn Poplar Bluff
Econo Lodge Dexter

Econo Lodge Dexter

8/10 Good
"Carpet was stinky. Handrails were loose. Air conditioner was working, but was unreliable and hard to control. Froze us out first night, then had to keep adjusting it. Parking lot was cracked and had broken pipes. Price was very reasonable, but you get what you pay for."
randy 2-night trip
Posted 11 days ago
Econo Lodge Dexter

More cheap stays in Puxico

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri

2831 N Westwood Blvd Poplar Bluff MO
€66
22 Aug - 23 Aug
includes taxes & fees
6.6/10 (663 reviews)
Super 8 by Wyndham Poplar Bluff Missouri
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

4101 Highway 67 N Poplar Bluff MO
€70
10 Aug - 11 Aug
includes taxes & fees
Motel 6 Poplar Bluff, MO
Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North

2582 N Westwood Blvd Poplar Bluff MO
€81
30 Aug - 31 Aug
includes taxes & fees
7.8/10 Good! (431 reviews)
Comfort Inn Poplar Bluff North
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

1608 E Business US 60 Dexter MO
€89
16 Aug - 17 Aug
includes taxes & fees
7.6/10 Good! (419 reviews)
Travelodge by Wyndham Dexter
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2420 Crestwood Dr Poplar Bluff MO
€93
6 Sept - 7 Sept
includes taxes & fees
Hampton Inn Poplar Bluff
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2179 Gill Plaza Drive Dexter MO
€95
16 Aug - 17 Aug
includes taxes & fees
9.6/10 Exceptional! (62 reviews)
Hampton Inn By Hilton Dexter

Frequently asked questions

What's the best place for a stay in Puxico?
Motel 6 Poplar Bluff, MO, located 19.4 mi (31.3 km) from the heart of Puxico, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Fairfield Inn & Suites by Marriott Poplar Bluff and Drury Inn & Suites Poplar Bluff. See all available top hotels, or vacation rentals in Puxico.
What are some of the best holiday rentals that Puxico has to offer?
Private lake, beach & hot tub, romantic getaway or family vaca: This holiday home rental outside of Puxico is equipped with 1 hot tub, air conditioning and laundry facilities to help you feel comfortable during your stay. See all vacation rentals in Puxico.
If I need to cancel my hotel reservation in Puxico, will I receive a refund?
Yes, you'll find most hotel bookings are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, it might still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Puxico.
What is staying in Puxico like?
Travellers to Puxico will find plenty to explore and enjoy. There are 55 hotels and other accommodation options in the surrounding area. Find out more about Puxico.
What is there to see in Puxico?
A couple of favourite places to visit are Mark Twain National Forest and Mingo Wilderness. You'll also find Lake Wappapello and Lake Wappapello State Park in the area. Take a look at what more there is to see and do in Expedia's Puxico guide.
What's the seasonal weather in Puxico?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Puxico is 1502 mm.

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