Rochester Hotel Guide - Rochester Museum and Science Center hotels in Rochester, United States of America.

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30 Dec - 31 Dec
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31 Dec - 1 Jan
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Rochester Museum and Science Center hotels

Restaurant
Hampton Inn & Suites Rochester Downtown

Hampton Inn & Suites Rochester Downtown

Hampton Inn & Suites Rochester Downtown
2.5 star property
Downtown Rochester, 0.9 km from Rochester Museum and Science Center
9.6 out of 10, Exceptional, (543)
"Our room was great, we loved the area, and Tanner at the desk was excellent"
United States
steve
The price is €134
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Rochester Downtown
Premium Double Room, Private Bathroom | Balcony view
Dartmouth House

Dartmouth House

Dartmouth House
4.0 star property
Park Avenue Historic District, 0.9 km from Rochester Museum and Science Center
9.6 out of 10, Exceptional, (225)
"A quaint B&B in a historic neighborhood"
United States
Ryan
The price is €183
includes taxes & fees
31 Dec - 1 Jan 2026
Dartmouth House
Property amenity
Courtyard by Marriott Rochester Downtown

Courtyard by Marriott Rochester Downtown

Courtyard by Marriott Rochester Downtown
3.0 star property
East Avenue, 0.6 km from Rochester Museum and Science Center
9.2 out of 10, Wonderful, (267)
"Beautiful room and courteous staff."
United States
Jessica Anne
The price is €147
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Rochester Downtown
Ballroom
Inn on Broadway

Inn on Broadway

Inn on Broadway
3.5 star property
Rochester Central Business District, 1.1 km from Rochester Museum and Science Center
9.0 out of 10, Wonderful, (851)
"Wonderful stay, staff was awesome, hotel was beautiful"
United States
Alana Denise
Inn on Broadway
Rooftop terrace
The Strathallan Rochester Hotel & Spa - DoubleTree by Hilton

The Strathallan Rochester Hotel & Spa - DoubleTree by Hilton

The Strathallan Rochester Hotel & Spa - DoubleTree by Hilton
4.0 star property
East Avenue, 0.2 km from Rochester Museum and Science Center
8.8 out of 10, Excellent, (921)
"Everything was great"
United States
Tony
The price is €134
includes taxes & fees
11 Jan - 12 Jan 2026
The Strathallan Rochester Hotel & Spa - DoubleTree by Hilton
Luxury Studio Suite (209) | Living area
School 31 Lofts at Colors Studios

School 31 Lofts at Colors Studios

School 31 Lofts at Colors Studios
2.5 star property
0.5 km from Rochester Museum and Science Center
8.8 out of 10, Excellent, (529)
"We really enjoyed our stay and are exciting to come back and check out other rooms. "
United States
Tioga
The price is €177
includes taxes & fees
1 Jan - 2 Jan 2026
School 31 Lofts at Colors Studios
Lobby
Hilton Garden Inn Rochester Downtown, NY

Hilton Garden Inn Rochester Downtown, NY

Hilton Garden Inn Rochester Downtown, NY
3.0 star property
Rochester Central Business District, 1.7 km from Rochester Museum and Science Center
8.2 out of 10, Very good, (852)
"The lady at the front desk was absolute incredible! She was warm and inviting and seemed enthusiastic to help the guests. "
United States
Justin
The price is €125
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Garden Inn Rochester Downtown, NY
Front of property – evening/night
Hyatt Regency Rochester

Hyatt Regency Rochester

Hyatt Regency Rochester
3.5 star property
Rochester Central Business District, 1.7 km from Rochester Museum and Science Center
7.4 out of 10, Good, (1001)
"Clean room, staff"
United States
Alexanderia
The price is €117
includes taxes & fees
18 Jan - 19 Jan 2026
Hyatt Regency Rochester
Breakfast and dinner served
Hilton Garden Inn Rochester/University & Medical Center

Hilton Garden Inn Rochester/University & Medical Center

Hilton Garden Inn Rochester/University & Medical Center
3.0 star property
Strong, 4.3 km from Rochester Museum and Science Center
9.2 out of 10, Wonderful, (1000)
"Great location with many options in short walking distance."
United States
Jeffrey
The price is €142
includes taxes & fees
15 Jan - 16 Jan 2026
Hilton Garden Inn Rochester/University & Medical Center
Exterior
Staybridge Suites Rochester University by IHG

Staybridge Suites Rochester University by IHG

Staybridge Suites Rochester University by IHG
3.0 star property
19th Ward, 4.7 km from Rochester Museum and Science Center
9.0 out of 10, Wonderful, (1002)
"Rooms were clean and front desk staff was very nice."
United States
Perkins
The price is €105
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Rochester University by IHG
Lobby sitting area
Oakfield Inn & Suites Rochester, an Ascend Collection Hotel

Oakfield Inn & Suites Rochester, an Ascend Collection Hotel

Oakfield Inn & Suites Rochester, an Ascend Collection Hotel
2.5 star property
Brighton, 5.4 km from Rochester Museum and Science Center
9.2 out of 10, Wonderful, (140)
"Clean room, reasonably priced, and looks to be a recent renovation"
United States
Michael
The price is €128
includes taxes & fees
28 Jan - 29 Jan 2026
Oakfield Inn & Suites Rochester, an Ascend Collection Hotel
Exterior
Country Inn & Suites by Radisson, Rochester-Pittsford/Brighton, NY

Country Inn & Suites by Radisson, Rochester-Pittsford/Brighton, NY

Country Inn & Suites by Radisson, Rochester-Pittsford/Brighton, NY
3.0 star property
Brighton, 5.7 km from Rochester Museum and Science Center
8.8 out of 10, Excellent, (1003)
"Very clean room, staff was nice, overall really nice time"
United States
Collin
The price is €113
includes taxes & fees
25 Jan - 26 Jan 2026
Country Inn & Suites by Radisson, Rochester-Pittsford/Brighton, NY
Reception
Hotel on Monroe, BW Signature Collection

Hotel on Monroe, BW Signature Collection

Hotel on Monroe, BW Signature Collection
2.5 star property
Brighton, 4.4 km from Rochester Museum and Science Center
8.2 out of 10, Very good, (383)
"For the price, this hotel was truly excellent"
United States
Deborah
The price is €90
includes taxes & fees
5 Jan - 6 Jan 2026
Hotel on Monroe, BW Signature Collection
Property amenity
Residence Inn by Marriott Rochester Henrietta

Residence Inn by Marriott Rochester Henrietta

Residence Inn by Marriott Rochester Henrietta
3.0 star property
7.4 km from Rochester Museum and Science Center
9.2 out of 10, Wonderful, (594)
"The room was clean and the staff was very friendly. "
United States
Tikesha
The price is €164
includes taxes & fees
1 Jan - 2 Jan 2026
Residence Inn by Marriott Rochester Henrietta
Free daily continental breakfast
Fairfield Inn Marriott Rochester Airport

Fairfield Inn Marriott Rochester Airport

Fairfield Inn Marriott Rochester Airport
2.5 star property
6.7 km from Rochester Museum and Science Center
8.6 out of 10, Excellent, (1006)
"Front desk was amazing and very helpful "
United States
Ricardo
The price is €118
includes taxes & fees
2 Jan - 3 Jan 2026
Fairfield Inn Marriott Rochester Airport
Exterior
Hampton Inn Rochester Irondequoit

Hampton Inn Rochester Irondequoit

Hampton Inn Rochester Irondequoit
2.5 star property
East Irondequoit, 5 km from Rochester Museum and Science Center
8.0 out of 10, Very good, (1006)
"The stay was nice as always"
United States
Ollie
The price is €75
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Rochester Irondequoit
Terrace/patio
Hampton Inn Rochester Penfield

Hampton Inn Rochester Penfield

Hampton Inn Rochester Penfield
2.5 star property
8.7 km from Rochester Museum and Science Center
9.2 out of 10, Wonderful, (1005)
"Clean room, cleanest pool & hot tub I've ever seen, terrific staff who go above & beyond, lovely breakfast!"
United States
Kathryn
The price is €106
includes taxes & fees
5 Jan - 6 Jan 2026
Hampton Inn Rochester Penfield
Exterior
Home2 Suites by Hilton Greece Rochester

Home2 Suites by Hilton Greece Rochester

Home2 Suites by Hilton Greece Rochester
3.0 star property
8.5 km from Rochester Museum and Science Center
9.0 out of 10, Wonderful, (506)
"Had a comfortable stay. Loved the drinks station."
Canada
Qurat ul ain
The price is €105
includes taxes & fees
11 Jan - 12 Jan 2026
Home2 Suites by Hilton Greece Rochester
Lobby
Courtyard by Marriott Rochester East/Penfield

Courtyard by Marriott Rochester East/Penfield

Courtyard by Marriott Rochester East/Penfield
3.0 star property
7.8 km from Rochester Museum and Science Center
8.8 out of 10, Excellent, (457)
"Friendly staff and helpful—-room was clean and tidy which is the number one thing we look for when staying at a hotel. The hotel overall was clean and quiet which is what we were looking for. We would definitely stay at this hotel again—hands down! If you choose this hotel you will not be disappointed. "
United States
Kerry
The price is €110
includes taxes & fees
12 Jan - 13 Jan 2026
Courtyard by Marriott Rochester East/Penfield
Meeting facility
The Del Monte Lodge Renaissance Rochester Hotel & Spa

The Del Monte Lodge Renaissance Rochester Hotel & Spa

The Del Monte Lodge Renaissance Rochester Hotel & Spa
4.0 star property
8.9 km from Rochester Museum and Science Center
9.2 out of 10, Wonderful, (321)
"Always a great place to stay!!!"
United States
Debra
The price is €208
includes taxes & fees
4 Jan - 5 Jan 2026
The Del Monte Lodge Renaissance Rochester Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Rochester Museum and Science Center Hotel Reviews

Hilton Garden Inn Rochester Downtown, NY

Hilton Garden Inn Rochester Downtown, NY

10/10 Excellent
"The lady at the front desk was absolute incredible! She was warm and inviting and seemed enthusiastic to help the guests. "
Justin 1-night trip
Posted 1 day ago
Hilton Garden Inn Rochester Downtown, NY

Hotels near other Rochester Museum and Science Center attractions

Memorial Art Gallery illuminated at dusk in Downtown Rochester, showcasing art and culture in New York

Memorial Art Gallery

From Ancient Egypt to Jackson Pollock and beyond, this sizable university museum brings works of art from the last 5,000 years to downtown Rochester.
See properties
George Eastman House which includes heritage architecture

George Eastman Museum

Once owned by the founder of Kodak, this opulent mansion features a huge collection of early photography equipment, interesting architecture and beautiful gardens.
See properties

Frequently asked questions

What's the area like around Rochester Museum and Science Center?
Rochester Museum and Science Center is located in a family-friendly area of Rochester known for its great live music scene and top museums. If you're looking for a convenient place to stay, take a look at the 107 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Rochester Museum and Science Center?
Adjacent to Rochester Museum and Science Center, The Strathallan Rochester Hotel & Spa - DoubleTree by Hilton is one of the top choices for your stay based on our traveller data, and this hotel offers a full-service spa and a restaurant. Other good choices within a short distance include Hampton Inn & Suites Rochester Downtown and School 31 Lofts at Colors Studios.
How many hotels can I expect to find close to Rochester Museum and Science Center?
Expedia has 107 hotels and other accommodation options within a mile from Rochester Museum and Science Center.
If I need to cancel the hotel reservation for my stay near Rochester Museum and Science Center, will I receive a refund?
Yes, most hotel bookings are fully refundable as long as you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you may still be able to cancel and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to get top deals close to Rochester Museum and Science Center.
What can I see and do near Rochester Museum and Science Center?
You might want to spend some time browsing the exhibits at Memorial Art Gallery, Susan B. Anthony House or Stone Tolan House Museum. George Eastman Museum, Main Street Armory and Pont de Rennes Bridge are monuments to see when you're exploring the area around Rochester Museum and Science Center. You can watch performances at Rochester Auditorium Theater, Kodak Center for Performing Arts and Dryden Theatre if you're interested in local theatre.
How can I get to Rochester Museum and Science Center?
If you want to explore the larger area, hop on a train at Rochester Station. There may not be many public transport choices close to Rochester Museum and Science Center so consider a car rental to maximise your time.