Cape Girardeau Hotel Guide - Saint Francis Medical Center hotels in Cape Girardeau, United States of America.

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
20 Nov - 21 Nov
Tomorrow
21 Nov - 22 Nov
This weekend
21 Nov - 23 Nov
Next weekend
28 Nov - 30 Nov

Filter by

Guest rating
Guest rating
Star rating

Top Trending Hotels Near Saint Francis Medical Center

Courtyard
Hampton Inn Cape Girardeau I 55 East

Hampton Inn Cape Girardeau I 55 East

2.5 star property
0.5 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (770)
"Excellent stay"
United States
Christina
The price is €97
includes taxes & fees
26 Nov - 27 Nov
Hampton Inn Cape Girardeau I 55 East
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
0.8 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (1001)
"Very nice stay."
United States
Charity
The price is €88
includes taxes & fees
1 Dec - 2 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
0.5 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (1001)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
The price is €89
includes taxes & fees
30 Nov - 1 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

3.0 star property
0.9 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (1002)
"Rooms are nice and big. Breakfast was above average and staff was very nice and friendly. "
United States
Sandra
The price is €88
includes taxes & fees
30 Nov - 1 Dec
Drury Inn & Suites Cape Girardeau
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
1.5 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (136)
"Great hotel!"
United States
Will
The price is €86
includes taxes & fees
7 Dec - 8 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
0.4 km from Saint Francis Medical Center
9.0 out of 10, Wonderful, (1001)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is €68
includes taxes & fees
24 Nov - 25 Nov
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property
1.6 km from Saint Francis Medical Center
8.0 out of 10, Very good, (872)
"Great room"
United States
Kevin
The price is €80
includes taxes & fees
7 Dec - 8 Dec
Candlewood Suites Cape Girardeau by IHG
Desk, free WiFi
Town House Inn Cape Giradreau

Town House Inn Cape Giradreau

2.5 star property
2 km from Saint Francis Medical Center
6.0 out of 10, (204)
"Along a main street but not a lot of noise, especially in the rooms. Rooms exit to the outdoors."
United States
Gary
The price is €71
includes taxes & fees
1 Dec - 2 Dec
Town House Inn Cape Giradreau
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

2.5 star property
0.8 km from Saint Francis Medical Center
9.0 out of 10, Wonderful, (1000)
"Great stay"
United States
Heather
The price is €68
includes taxes & fees
24 Nov - 25 Nov
Pear Tree Inn Cape Girardeau West
Standard Room, 1 Queen Bed, Non Smoking, Garden View
Rockwood Inn

Rockwood Inn

2.0 star property
3.6 km from Saint Francis Medical Center
10.0 out of 10, Exceptional, (17)
"We came into town for a concert and had a blast! The hotel was super comfy, and the staff were friendly. The rooms were very clean and the decor was beautiful! "
United States
Vanessa
The price is €146
includes taxes & fees
23 Nov - 24 Nov
Rockwood Inn
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
4.3 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (463)
"The staff was very helpful and friendly. The rooms were modern and clean. The downtown location was perfect for us. "
United States
Deborah
The price is €114
includes taxes & fees
29 Nov - 30 Nov
Courtyard by Marriott Cape Girardeau Downtown
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

2.5 star property
5.7 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (94)
"It was a nice stay"
United States
Douglas
The price is €86
includes taxes & fees
7 Dec - 8 Dec
Tru By Hilton Cape Girardeau
Lobby sitting area
The Riverview

The Riverview

4.0 star property
4.9 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (456)
"Place was nice and safe"
United States
ryan
The price is €94
includes taxes & fees
1 Dec - 2 Dec
The Riverview
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
6.7 km from Saint Francis Medical Center
8.8 out of 10, Excellent, (651)
"Stayed on our way south for vacation. It was a clean nice place to stay. "
United States
Joel
The price is €79
includes taxes & fees
2 Dec - 3 Dec
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Comfort Suites Jackson-Cape Girardeau

Comfort Suites Jackson-Cape Girardeau

2.5 star property
6.7 km from Saint Francis Medical Center
8.2 out of 10, Very good, (738)
"Dirty "
United States
Jon
The price is €77
includes taxes & fees
7 Dec - 8 Dec
Comfort Suites Jackson-Cape Girardeau
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property
15.3 km from Saint Francis Medical Center
9.6 out of 10, Exceptional, (1007)
"This was a wonderful stay. We will definitely stay again when we are in town!"
United States
Trista
The price is €82
includes taxes & fees
24 Nov - 25 Nov
Drury Inn & Suites Jackson MO
Lobby
Quality Inn

Quality Inn

2.5 star property
3.8 km from Saint Francis Medical Center
7.2 out of 10, Good, (674)
"Overall was wonderful customer service and breakfast"
United States
Stephanie
The price is €56
includes taxes & fees
26 Nov - 27 Nov
Quality Inn
Exterior
La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau

2.0 star property
6.5 km from Saint Francis Medical Center
9.4 out of 10, Exceptional, (3)
"Nice place "
United States
jermaine
La Quinta Inn & Suites by Wyndham Jackson/cape Girardeau
Economy Single Room, 1 Queen Bed, Kitchenette
Town House Inn

Town House Inn

2.5 star property
11.4 km from Saint Francis Medical Center
7.6 out of 10, Good, (422)
"Room was clean and had a refrigerator and microwave for use if needed."
United States
Sherry
The price is €66
includes taxes & fees
23 Nov - 24 Nov
Town House Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Hotels close to Saint Francis Medical Center with free breakfast

Courtyard
Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 East
2.5 star property
  • Breakfast included
9.6 out of 10, Exceptional, (770)
The price is €97
includes taxes & fees
26 Nov - 27 Nov
Hampton Inn Cape Girardeau I 55 East
See more properties

Hotels close to Saint Francis Medical Center with a pool

Exterior
Candlewood Suites Cape Girardeau by IHG
Candlewood Suites Cape Girardeau by IHG
2.5 star property
  • Pool
8.0 out of 10, Very good, (872)
The price is €80
includes taxes & fees
7 Dec - 8 Dec
Candlewood Suites Cape Girardeau by IHG
See more properties

Top guest rated hotels close to Saint Francis Medical Center

Standard Room, 1 Queen Bed, Non Smoking, Garden View
Rockwood Inn
Rockwood Inn
2.0 star property
    10.0 out of 10, Exceptional, (17)
    The price is €146
    includes taxes & fees
    23 Nov - 24 Nov
    Rockwood Inn
    See more properties

    Top Saint Francis Medical Center Hotel Reviews

    Drury Plaza Hotel Cape Girardeau Conference Center

    Drury Plaza Hotel Cape Girardeau Conference Center

    10/10 Excellent
    "Clean rooms. Very comfortable bed. Friendly staff "
    Donna 1-night trip
    Posted 3 days ago
    Drury Plaza Hotel Cape Girardeau Conference Center

    Hotels near other Saint Francis Medical Center attractions

    Panorama of Academic Hall, Southeast Missouri State University

    Southeast Missouri State University

    4.4/5 (137 reviews)
    Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
    See properties
    View of the Christopher S. Bond Bridge over Missouri River in Kansas City, from the riverfront park

    Riverfront Bridge Park

    4.4/5 (74 reviews)
    Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savour the top-notch restaurants.
    See properties

    Frequently asked questions

    What's the area like around Saint Francis Medical Center?
    Saint Francis Medical Center is located in Cape Girardeau. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
    What's the best hotel to stay near Saint Francis Medical Center?
    Adjacent to Saint Francis Medical Center, Pear Tree Inn Cape Girardeau Near the Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free WiFi and LCD TVs. Other good choices within a short distance include Drury Plaza Hotel Cape Girardeau Conference Center and Pear Tree Inn Cape Girardeau West.
    How many hotels are there close to Saint Francis Medical Center?
    Expedia has 9 hotels and other accommodation options within a mile from Saint Francis Medical Center.
    If I need to cancel the hotel reservation for my stay near Saint Francis Medical Center, will I receive a refund?
    Yes! The majority of hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to review the best options available near Saint Francis Medical Center.
    What can I see and do near Saint Francis Medical Center?
    You might spend a leisurely day outdoors at Fort D Historic Site and Cape Rock Park. Create some family memories at Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center. You might plan a visit to Show Me Center or eDen Spa & Salon while you're in the area.

    Explore a world of travel with Expedia