Santa Ana hotels, Panama City, Panama: Panama City Hotel Guide

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Compare popular hotels in Santa Ana

Property	Property class	Guest rating
Casco View Apartments	3.5 star property	9.0 Wonderful 100 reviews	View
Hostal La Cigarra	2.0 star property	7.6 Good 73 reviews	View
Hotel República	2.0 star property	6.8 195 reviews	View
ART CASCO The Hotel	2.0 star property	6.0 11 reviews	View
Hotel Riazor	3.0 star property	3.8 11 reviews	View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A spiraling skyscraper against a clear blue sky.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

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A bridge over a body of water with several boats.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

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A coastal cityscape with high-rise buildings, a calm sea, and a rocky shoreline.

Calidonia

Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.

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Top Santa Ana Hotel Reviews

Hotel Riu Plaza Panama

10/10 Excellent

"Located in an ideal location and definitely would book again. Enjoyed my stay. 10/10."

The Executive Hotel

8/10 Good

"I love that breakfast was included, I didn't always love the selection. The resturant had excellent food at a decent price, we dined their often. It's less than a 5 minute walk from the metro. Lots of fast food resturants near by. Speaking to the staff was difficult due to the language barrier, but we managed to understand each other. They held our luggage will we spent the last day in the city. I enjoyed my stay at the hotel it was in a great location."

Central Hotel Panama Casco Viejo

10/10 Excellent

"Beautiful hotel with great history! The location in Casco Viejo was perfect for our visit to Panama City and we were easily able to walk or order a car/Uber from there for various trips. We had a family suite, which was a king and full size bed room that worked well for our family of 3. The rooftop pool is small, but lovely and the restaurant near the pool was great with friendly staff. The Central Hotel is a gorgeous place and the staff at the front desk, door and restaurants were all nice and helpful."

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Ana?

Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.

How many hotels can I expect to find in Santa Ana?

Expedia has 120 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.

What is there to do in this Panama City neighbourhood?

If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

Panama City Hotel Guide. Hotels in Santa Ana, Panama City, Panama

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Our top choices for Santa Ana hotels

Casco View Apartments

Hostal La Cigarra

Hotel Riazor

La Manzana Barrio Vivo by Wynwood

Hotel República

Room-sofa Bed Stay Rooftop Pool & Gym, A

ART CASCO The Hotel

Crowne Plaza Panama Airport by IHG

Riande Aeropuerto Hotel & Casino

ORHO Hotel Boutique 15 Minutes from PTY Airport

Villa Caprichosa

Arcadia Condo Suites

Gamboa Rainforest Reserve

The Beach House

Radisson Hotel Panama Canal

The Westin Playa Bonita Panama

Courtyard by Marriott Panama Metromall

MARINN Tropical Vibes Hotel

Best Western El Dorado Panama Hotel

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Compare popular hotels in Santa Ana

Where to stay in Santa Ana

Casco Viejo

Bella Vista

El Cangrejo

San Francisco

Calidonia

Top Santa Ana Hotel Reviews

Hotel Riu Plaza Panama

Frequently asked questions