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Cusco Hotel Guide. Hotels in Santa Ana, Cusco, Peru

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27 Dec - 28 Dec
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28 Dec - 29 Dec
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2 Jan - 4 Jan
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9 Jan - 11 Jan

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Our top choices for Santa Ana hotels

Restaurant
Hilton Garden Inn Cusco

Hilton Garden Inn Cusco

Hilton Garden Inn Cusco
3.5 star property
Santa Ana
9.2 out of 10, Wonderful, (1001)
"great hotel"
United States
Rodolfo
The price is €106
8 Jan - 9 Jan 2026
Hilton Garden Inn Cusco
Daily buffet breakfast for a fee
Centro by Casa Andina Cusco Saphi

Centro by Casa Andina Cusco Saphi

Centro by Casa Andina Cusco Saphi
3.0 star property
Santa Ana
9.0 out of 10, Wonderful, (12)
"A pleasant place to visit Cuzco"
France
Michel
Centro by Casa Andina Cusco Saphi
Design Suite, Patio
ZEVEN HOUSE - CUSCO APARTMENT

ZEVEN HOUSE - CUSCO APARTMENT

ZEVEN HOUSE - CUSCO APARTMENT
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (1)
"My wife and I are visiting Cusco from Dallas, Texas. We had a wonderful stay. The host spoke English and was very kind and helpful. He showed us how to operate the appliances. There was hot water in the shower, a gas stove, washing machine, refrigerator, TV with Netflix (big plus), and electric portable space heater (another big plus). The beds were very comfortable and warm. Wi-fi was fast and reliable. The place was quiet at night. Short walking distance to Orion grocery store. Definitely...
United States
Andrew
The price is €42
28 Dec - 29 Dec
ZEVEN HOUSE - CUSCO APARTMENT
Room
Hotel Cusco Pacha Inti

Hotel Cusco Pacha Inti

Hotel Cusco Pacha Inti
3.0 star property
Santa Ana
6.0 out of 10, (1)
"El hotel cumple con sus funciones, sin embargo es complicado el tema de la regadera, considero es un punto que pueden mejorar. El hotel no está alejado del centro pero está en una zona no tan cómoda de llegar, ni siquiera los autos tienen accedió tan fácil. El personal es muy atento y amable, sin embargo tuve que pagar dos veces la reservación porque a ellos "no se les reflejaba" siendo que ellos mismos confirmaron que tienen problemas con expedis y Booking y a pesar de que les mostré en mi...
Mexico
CR
The price is €25
28 Dec - 29 Dec
Hotel Cusco Pacha Inti
Terrace/patio
Munay Cusco

Munay Cusco

Munay Cusco
2.0 star property
Santa Ana
Munay Cusco
Terrace/patio
Hotel El Mirador de Santa Ana

Hotel El Mirador de Santa Ana

Hotel El Mirador de Santa Ana
3.0 star property
Santa Ana
The price is €28
28 Dec - 29 Dec
Hotel El Mirador de Santa Ana
Deluxe Room
Anata Hostel

Anata Hostel

Anata Hostel
3.0 star property
Santa Ana
8.8 out of 10, Excellent, (21)
"Great location, staff incredible!"
Canada
christiane
The price is €20
1 Jan - 2 Jan 2026
Anata Hostel
TV
Munay Ñusta Cusco

Munay Ñusta Cusco

Munay Ñusta Cusco
3.0 star property
Santa Ana
9.6 out of 10, Exceptional, (4)
"Very nice property"
United States
Arthur
Munay Ñusta Cusco
Terrace/patio
Santa Ana Departamentos

Santa Ana Departamentos

Santa Ana Departamentos
2.0 star property
Santa Ana
9.0 out of 10, Wonderful, (4)
"Grand appartement à 10 min à pied de la place des Armes. Il y a également un bus qui s'arrête devant le portail. Nous sommes toujours descendus à pied et remontés en navette. Eau chaude, appartement un peu froid mais pas insurmontable. Accueil très sympathique et agréable de la part des propriétaires, n'hésitez pas à leur demander conseils ou de l'aide ils feront tout pour vous aider. Nous avons passé un excellent séjour grâce à eux."
France
Mélissa
Santa Ana Departamentos
Terrace/patio
Tierra Viva Cusco Saphi

Tierra Viva Cusco Saphi

Tierra Viva Cusco Saphi
3.0 star property
Santa Ana
9.4 out of 10, Exceptional, (500)
"Great place ! "
United States
Roger
Tierra Viva Cusco Saphi
Free daily buffet breakfast
Hotel Mamasara

Hotel Mamasara

Hotel Mamasara
3.0 star property
Santa Ana
8.4 out of 10, Very good, (18)
"It was nice"
United States
Alexander
Hotel Mamasara
Family Apartment, 2 Bedrooms, City View
Casa Karmenka

Casa Karmenka

Casa Karmenka
2.5 star property
Santa Ana
Casa Karmenka
Terrace/patio
Tucan Hostel

Tucan Hostel

Tucan Hostel
2.0 star property
Santa Ana
8.4 out of 10, Very good, (14)
"We found this hostel to be a very special place, filled with wonderfully helpful and pleasant folks. We would highly recommend a stay."
United States
Anonymous traveller
The price is €26
3 Jan - 4 Jan 2026
Tucan Hostel
Garden
HOSTAL LA RASA

HOSTAL LA RASA

HOSTAL LA RASA
2.0 star property
Santa Ana
10.0 out of 10, Exceptional, (2)
"Accueil très agréable !"
France
Lia
The price is €17
28 Dec - 29 Dec
HOSTAL LA RASA
Reception
LP Los Portales Hotel Cusco

LP Los Portales Hotel Cusco

LP Los Portales Hotel Cusco
3.5 star property
Cusco Historic Center, 1.4 km from Santa Ana
9.4 out of 10, Exceptional, (782)
"Clean sheets and bed comfy pillows clean bath tub with jets. We had a great time with my husband. Room was quiet and affordable. Stuff was very nice and helpful. Free tea anytime and room service was nice. Soup is instant one so pass that but main dishes were good"
United States
Sinem
The price is €56
17 Jan - 18 Jan 2026
LP Los Portales Hotel Cusco
Terrace/patio
Union Hotel Cusco

Union Hotel Cusco

Union Hotel Cusco
3.5 star property
Cusco Historic Center, 0.5 km from Santa Ana
9.2 out of 10, Wonderful, (1000)
"Love this place, all the staff was very friendly, we love KIKI"
United States
Jesus Daniel
Union Hotel Cusco
Front of property – evening/night
Ureta Hotel

Ureta Hotel

Ureta Hotel
3.5 star property
Rosaspata, 2.3 km from Santa Ana
9.6 out of 10, Exceptional, (648)
"Rooms were clean, breakfasts were great and the staff was amazing "
United States
jeremiah
The price is €45
30 Dec - 31 Dec
Ureta Hotel
Interior detail
Abittare Hotels

Abittare Hotels

Abittare Hotels
3.0 star property
Cusco Historic Center, 1.2 km from Santa Ana
9.0 out of 10, Wonderful, (377)
"Good, clean and nice hotel "
United States
Silvana
The price is €63
24 Jan - 25 Jan 2026
Abittare Hotels
Courtyard
Andenes

Andenes

Andenes
2.5 star property
San Blas, 1.1 km from Santa Ana
9.6 out of 10, Exceptional, (101)
"Beautiful fusion of classic Andean architecture with modern and clean facilities. Very cozy and good breakfast. "
United States
Antonio Jose
The price is €59
11 Jan - 12 Jan 2026
Andenes
Single Room, 1 Queen Bed
San Francisco Cusco Hotel

San Francisco Cusco Hotel

San Francisco Cusco Hotel
2.5 star property
Progreso, 3.8 km from Santa Ana
8.6 out of 10, Excellent, (98)
"Only stayed for one night and the bed was nice"
Canada
Mark
The price is €25
28 Dec - 29 Dec
San Francisco Cusco Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.
La Merced Church showing a city

Cusco Historic Center

Cusco Historic Center is known for its popular shops, and with sights like Santa Catalina Convent and Coricancha, you won't get bored spending a day wandering around this part of Cusco.

San Blas which includes a city

San Blas

Take a walk through the heart of Cusco’s artisan district, one of the city’s most beguiling and lively areas.

San Cristóbal

While visiting San Cristóbal, you might make a stop by sights like Plaza Sán Cristobal and Museo de Arte Precolombino.

Santa Monica

While Santa Monica may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Real Plaza Cusco and Ttio Market.

Santiago

If you're looking for some top things to see and do in Santiago and surrounding area, you can visit Ttio Market and Santiago Plaza.

Top Santa Ana Hotel Reviews

Antigua Casona San Blas

Antigua Casona San Blas

10/10 Excellent
"Amazing room, staff service and food quality. Although it is an uphill walk from central Cusco it is worth the effort for the best hotel experience. The staff are at hand for anything you need. They are all extremely polite and friendly. Highly recommend. "
Susan 3-night trip
Posted 18 hours ago
Antigua Casona San Blas

Frequently asked questions

What is Santa Ana like?
Travellers to Cusco's Santa Ana neighbourhood will be sure to enjoy a stay here.
What's a favourite place to stay in Santa Ana?
Based on Expedia customer reviews, Hilton Garden Inn Cusco is the highest ranked property in Santa Ana. This hotel is a short 11-minute walk from Plaza de Armas, and it offers 2 bars and a restaurant. Another favourite option in the neighbourhood is Tierra Viva Cusco Saphi.
How many hotels should I expect to find in the Santa Ana area?
If you're searching for places to stay in Cusco, Expedia has something to meet your needs with 41 Santa Ana hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable if cancelled before the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a non-refundable reservation, you might still have the option to cancel and get a refund within 24 hours of booking. Enter dates in and click on "Search", then you can filter by "fully refundable" to view top deals in Santa Ana.
What can I see and do in this Cusco neighbourhood?
A few places to visit in the area around Santa Ana include Museo Irq'i Yachay, Museo de Plantas Sagradas Magicas y Medicinales and San Francisco Church Museum and Catacombs. Museum of Contemporary Art and ChocoMuseum are also worth a visit when you're out sightseeing in Cusco.