Panama City Hotel Guide. Hotels in Santa Ana, Panama City, Panama

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Our top choices for Santa Ana hotels

Casco View Apartments

Casco View Apartments
3.5 star property
Santa Ana
9.0 out of 10, Wonderful, (81 reviews)
"I would definitely stay here again! The immediate surrounding neighborhood is a little run down, but it’s much better only a few blocks over. The property itself is still really nice and its really convenient walk to Casco Viejo. "
United States
Kelsey
Casco View Apartments

Hostal La Cigarra

Hostal La Cigarra
2.0 star property
Santa Ana
7.6 out of 10, Good, (65 reviews)
"Excelente "
Mexico
David
Hostal La Cigarra

La Manzana by Wynwood House

La Manzana by Wynwood House
3.0 star property
Santa Ana
7.2 out of 10, Good, (15 reviews)
"Great hotel. Very close to Casco viejo"
United States
LUCILA
The price is €95
includes taxes & fees
26 Mar - 27 Mar
La Manzana by Wynwood House

ART CASCO The Hotel

ART CASCO The Hotel
2.0 star property
Santa Ana
6.0 out of 10, (11 reviews)
"Walkable location and free secure parking! The price is really affordable, but the condition of the hotel is not the best"
United States
Eldris
ART CASCO The Hotel

Hotel República

Hotel República
2.0 star property
Santa Ana
6.6 out of 10, (188 reviews)
"It's meant for a short stay, close to Casco Viejo and coast line. Clean bed and bathroom. Needs some maintenance. Beware, there's no hot water if that's a deal breaker for you."
United States
Mario
Hotel República

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
19.8 km from Santa Ana
8.4 out of 10, Very good, (1,870 reviews)
"Perfect place to stay before our flight."
United States
Shawn
The price is €118
includes taxes & fees
28 Mar - 29 Mar
Riande Aeropuerto Hotel & Casino

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
21.1 km from Santa Ana
8.6 out of 10, Excellent, (2,494 reviews)
"Great bed, quiet even though you are near the airport"
United States
howard matt
The price is €128
includes taxes & fees
23 Apr - 24 Apr
Crowne Plaza Panama Airport by IHG

Gamboa Rainforest Reserve

Gamboa Rainforest Reserve
3.5 star property
24.7 km from Santa Ana
8.0 out of 10, Very good, (723 reviews)
"Clean room, kind staff, good amenities and beautiful place with a lot of nature."
United States
Kazumi
The price is €144
includes taxes & fees
1 Apr - 2 Apr
Gamboa Rainforest Reserve

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
20.5 km from Santa Ana
8.8 out of 10, Excellent, (89 reviews)
"Nice people & room was nice"
United States
KAREN
The price is €134
includes taxes & fees
1 Apr - 2 Apr
ORHO HOTEL BOUTIQUE PANAMA Airport

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este, 10.2 km from Santa Ana
9.4 out of 10, Exceptional, (247 reviews)
"The stay was wonderful and seamless they are very friendly and efficient as always"
United States
Clifford
The price is €153
includes taxes & fees
26 Mar - 27 Mar
Arcadia Condo Suites

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz, 12.7 km from Santa Ana
9.6 out of 10, Exceptional, (679 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is €236
includes taxes & fees
5 Apr - 6 Apr
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama
5.0 star property
Campo Alegre, 3.6 km from Santa Ana
9.0 out of 10, Wonderful, (5,151 reviews)
"It was an excellent area overall for staying. "
United States
Kadiean
The price is €148
includes taxes & fees
30 Mar - 31 Mar
Hotel Riu Plaza Panama

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
14.7 km from Santa Ana
9.0 out of 10, Wonderful, (1,005 reviews)
"Staff and facilities excellent. "
United States
August H.
The price is €108
includes taxes & fees
7 Apr - 8 Apr
Courtyard by Marriott Panama Metromall

Villa Caprichosa

Villa Caprichosa
3.0 star property
18.3 km from Santa Ana
9.8 out of 10, Exceptional, (57 reviews)
"Would definitely visit again "
United States
John
The price is €186
includes taxes & fees
12 Apr - 13 Apr
Villa Caprichosa

JW Marriott Panama

JW Marriott Panama
5.0 star property
Punta Pacifica, 4.3 km from Santa Ana
9.0 out of 10, Wonderful, (1,002 reviews)
"Very enjoyable stay"
Canada
Lynnette
The price is €265
includes taxes & fees
9 Apr - 10 Apr
JW Marriott Panama

Hyatt Regency Panama City

Hyatt Regency Panama City
5.0 star property
Campo Alegre, 3.3 km from Santa Ana
9.6 out of 10, Exceptional, (229 reviews)
"Great staff and the food was amazing. "
United States
Nyrisha
The price is €113
includes taxes & fees
28 Mar - 29 Mar
Hyatt Regency Panama City

The Beach House

The Beach House
3.0 star property
Amador, 4.8 km from Santa Ana
8.4 out of 10, Very good, (424 reviews)
"We loved the staff, room & view! "
United States
Jerome
The Beach House

The Westin Playa Bonita Panama

The Westin Playa Bonita Panama
5.0 star property
7.5 km from Santa Ana
8.0 out of 10, Very good, (1,003 reviews)
"nice hotel, quality food, friendly staff, nice pools. "
United States
christopher
The price is €208
includes taxes & fees
10 Apr - 11 Apr
The Westin Playa Bonita Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco, 5.1 km from Santa Ana
9.6 out of 10, Exceptional, (1,157 reviews)
"Clean, spacious rooms, very nice and welcoming staff. Great breakfast. "
United States
Erica
The price is €89
includes taxes & fees
29 Mar - 30 Mar
Ramada Plaza by Wyndham Panama Punta Pacifica

Plaza Paitilla Inn Hotel

Plaza Paitilla Inn Hotel
3.5 star property
Punta Paitilla, 3.4 km from Santa Ana
9.4 out of 10, Exceptional, (2,137 reviews)
"excellent value for the money with a very good breakfast buffet"
Canada
Gary
The price is €119
includes taxes & fees
12 Apr - 13 Apr
Plaza Paitilla Inn Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Casco View Apartments
3.5 star property
9.0
Wonderful
81 reviews
View
Bar (on property)
Hostal La Cigarra
2.0 star property
7.6
Good
65 reviews
View
Double Room | View from room
Hotel República
2.0 star property
6.6
188 reviews
View
Front of property
ART CASCO The Hotel
2.0 star property
6.0
11 reviews
View
Café
Hotel Doral
2.5 star property
6.2
29 reviews
View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Fiesta Casino might round out your trip.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

San Felipe

While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.

Top Santa Ana Hotel Reviews

Frequently asked questions

What's it like in Santa Ana?
Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Cinta Costera and Avenida Balboa while you're in the neighbourhood.
Where is the best hotel for a stay in Santa Ana?
Based on Expedia customer reviews, Hotel República is the highest ranked property in Santa Ana. This hotel is a short 4-minute walk from Avenida Balboa, and it offers a rooftop terrace and free WiFi. Another top choice in the area is Hostal La Cigarra.
How many hotels can I expect to find in Santa Ana?
Expedia has 116 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.
If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.
What is there to do in this Panama City neighbourhood?
If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana, Avenida Central and Avenida Balboa, and pick out the perfect souvenir. A visit to Cinta Costera is also worth the trip while you're discovering the neighbourhood. Albrook Shopping Mall, Amador Theater and Museum of Contemporary Art Panama are just a few of the places to visit in and around Santa Ana. When you're sightseeing in Panama City, Mi Pueblito and Iglesia de la Merced are also worth a stop.