Santa Ana hotels, Panama City, Panama: Panama City Hotel Guide

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Compare popular hotels in Santa Ana

Property	Property class	Guest rating
Casco View Apartments	3.5 star property	9.0 Wonderful 105 reviews	View
Hostal La Cigarra	2.0 star property	7.6 Good 73 reviews	View
La Manzana Barrio Vivo by Wynwood	3.0 star property	7.6 Good 18 reviews	View
Hotel República	2.0 star property	6.8 196 reviews	View
Hotel Caracas - Casco Viejo	3.0 star property	9.0 Wonderful 2 reviews	View

Where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

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A spiraling skyscraper against a clear blue sky.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

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A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.

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A bridge over a body of water with several boats.

San Francisco

San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.

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A cityscape at sunset with tall buildings silhouetted against the sky.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

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Top Santa Ana Hotel Reviews

Central Hotel Panama Casco Viejo

10/10 Excellent

"great place."

The Executive Hotel

10/10 Excellent

"I had an overall great stay at The Executive Hotel in Panama. The staff were friendly and welcoming, and the room was comfortable and well maintained. I also really appreciated the location it was convenient and within easy reach of plenty of restaurants, shops, and other businesses, which made getting around and finding food very easy. Overall, it was a comfortable and convenient place to stay during my trip to Panama. I had a positive experience and would definitely recommend it to anyone looking for a well-located hotel in the city."

Casco View Apartments

10/10 Excellent

"The apartment was beautifully decorated, modern, and clean. The staff are friendly, extremely resourceful, and caring. They went above and beyond to ensure my deliveries, including prescriptions and food, were received. The staff also referred me to a wonderful Logistics Manager who drove and accompanied me to all of my appointments. A top-tier experience. Best customer service I've experienced in years!"

Frequently asked questions

What's it like in Santa Ana?

Santa Ana is a neighbourhood that travellers like for its seafood restaurants, shopping and parks. Are you looking for Santa Ana travel tips? Make sure that you visit Avenida Balboa and El Machetazo Santa Ana while you're in the neighbourhood.

Where is the best hotel for a stay in Santa Ana?

Based on our traveller data, Casco View Apartments is one of the top choices for your stay in Santa Ana. This condo is a short 8-minute walk from Avenida Balboa, and it offers an outdoor pool and in-room kitchens.

How many hotels can I expect to find in Santa Ana?

Expedia has 134 hotels and other accommodation options in Santa Ana to choose from, making this an ideal home base for exploring the greater Panama City area.

If I need to cancel my hotel reservation in Santa Ana, will I receive a refund?

Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view the best options available in Santa Ana.

What is there to do in this Panama City neighbourhood?

If you're looking forward to a day of shopping in Santa Ana, consider El Machetazo Santa Ana or Avenida Balboa, and pick out the perfect souvenir. When you're sightseeing in Panama City, Albrook Shopping Mall and Avenida Central are also worth a stop.

Panama City Hotel Guide. Hotels in Santa Ana, Panama City, Panama

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Our top choices for Santa Ana hotels

1. Casco View Apartments

2. Hostal La Cigarra

3. Hotel República

4. Hotel Riazor

5. La Manzana Barrio Vivo by Wynwood

6. ART CASCO The Hotel

7. Hotel Caracas - Casco Viejo

8. Room-sofa Bed Stay Rooftop Pool & Gym, A

9. Hotel Casa Panamá

10. La Concordia Boutique Hotel

11. Hotel Magnolia Boutique

12. Central Hotel Panama Casco Viejo

13. Hotel San Felipe

14. Oasis Hotel

15. Tantalo Hotel

16. Amarla Boutique Hotel Casco Viejo Adults Only

17. Sofitel Legend Casco Viejo, Panama City

18. Hotel La Compañía Casco Antiguo

19. Hotel Caribe

20. Canova

Compare popular hotels in Santa Ana

Where to stay in Santa Ana

Casco Viejo

Bella Vista

El Cangrejo

San Francisco

Punta Paitilla

Top Santa Ana Hotel Reviews

Central Hotel Panama Casco Viejo

Frequently asked questions