
Santa Clara Holidays
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Where to stay in Santa Clara
Find the best Santa Clara areas and neighborhoods for the activities you enjoy most. Learn more about Santa Clara

Casco Viejo
3.5/5(3 area reviews)
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Metropolitan Cathedral of Panama or Interoceanic Canal Museum while you're exploring the area.
Top hotels in Santa Clara

Hotel Riu Plaza Panama
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is €122 per night from 29 Jul to 30 Jul
€122
29 Jul - 30 Jul
includes taxes & fees
9/10 Wonderful! (4,109 reviews)
"Great"
Reviewed on 14 Jul 2025

Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz, Veracruz, Panama
Fully refundableReserve now, pay when you stay
The price is €205 per night from 17 Aug to 18 Aug
€205
17 Aug - 18 Aug
includes taxes & fees
7.2/10 Good! (1,003 reviews)
"Awesome stay! Everything is on the resort that you need."
Reviewed on 15 Jul 2025

Sheraton Grand Panama
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is €118 per night from 25 Jul to 26 Jul
€118
25 Jul - 26 Jul
includes taxes & fees
8.4/10 Very Good! (899 reviews)
"Good"
Reviewed on 15 Jul 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Things to do

Half day of Panama city and canal tour: shared and private
€57
per adult
98% of travellers recommend

Day Tour in San Blas Islands All Included Visiting 4 Islands
€127
per adult
94% of travellers recommend
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.