A large brick church with two bell towers and palm trees in front.

Santa Cruz de la Sierra Hotels

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Check prices for these dates

Tonight
6 Oct - 7 Oct
Tomorrow
7 Oct - 8 Oct
This weekend
9 Oct - 11 Oct
Next weekend
16 Oct - 18 Oct

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Our top choices for Santa Cruz de la Sierra hotels

A stone building with a tiled roof, a stone patio, and a grassy area.
A checkered floor, a staircase, and a reception desk in a building with yellow walls and green doors.
A rustic bar area with wooden stools, a checkered tablecloth, and a brick wall.
An outdoor dining area with stone flooring, tables, and chairs, surrounded by greenery and a stone building.

1. Hospedium Hotel Soterraña

Hospedium Hotel Soterraña
Madronera
United States
Jose Luis
€70
includes taxes & fees
7 Oct - 8 Oct
Hospedium Hotel Soterraña
A sunset view with a stone pathway, trees, and a fence.
A modern hotel room with a large bed, a flat-screen TV, a desk with a phone and a small table, and a view of the city through large windows.
A wine cellar with wooden racks and a bar area.
A modern building with a white facade, a red-tiled roof, and a large tree in the center.

2. Finca la Desa

Finca la Desa
Miajadas
New Zealand
Craig
€68
includes taxes & fees
7 Oct - 8 Oct
Finca la Desa
A historic stone courtyard with cobblestone flooring, a central fountain, and buildings with traditional architecture.
A swimming pool with lounge chairs and a stone building in the background.
A banquet hall with round tables, red chairs, and a high arched ceiling.
A corridor with stone arches, a wooden cabinet with glass doors, a table with a lamp, and a door at the end.

3. Parador de Trujillo

Parador de Trujillo
Trujillo
United States
wilton
€80
includes taxes & fees
2 Nov - 3 Nov
Parador de Trujillo
A historic building with a sign for "Eurostars" and a large entrance door.
A swimming pool with lounge chairs and a tower structure in the background.
A reception area with a wooden counter, a glass door, and a stone wall.
A balcony with a bench and a cup, overlooking a historic cityscape with buildings and a clear sky.

4. Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta
Trujillo
United Kingdom
Elizabeth
€65
includes taxes & fees
2 Nov - 3 Nov
Eurostars Palacio Santa Marta
A courtyard with white buildings, a cobblestone path, and potted plants.
A dining area with a wooden table, chairs, a patterned rug, a window with a view of trees, and a bookshelf.
A covered outdoor seating area with a stone floor, white walls, and arches.
A white-walled room with a large arched mirror, a red vase with green plants, and wooden boxes on a bench.

5. Finca El Azahar

Finca El Azahar
Trujillo
Canada
Alex
€151
includes taxes & fees
7 Oct - 8 Oct
Finca El Azahar
A lobby with a wooden cart displaying food and drinks, surrounded by arches and potted plants.
A banquet hall with a long table set for a formal event, arched ceilings, and a view of the upper level.
A pool area with a tiled deck, lounge chairs, and a table with candles.
A corridor with red walls, stone columns, and a tiled floor.

6. Hotel Izan Trujillo

Hotel Izan Trujillo
Trujillo
Spain
Monica
€76
includes taxes & fees
2 Nov - 3 Nov
Hotel Izan Trujillo
A stone-walled dining area with tables set for two, each with a red tablecloth and wine glasses.
A garden with various flowering plants and a stone wall in the background.
A building with a sign reading "HOTEL RESTAURANT LÉON".
A room with a bed, a wooden chair, and a vase with branches.

7. Hostal León

Hostal León
Trujillo
United Kingdom
Gareth
€55
includes taxes & fees
8 Oct - 9 Oct
Hostal León
A restaurant with checkered tablecloths, wooden chairs, and a stone wall.
A bar area with brick walls, a wooden bar counter, and black bar stools.
A stone building with a sign that reads "RESORT".
A hallway with a brick archway, a staircase, and a potted plant.

8. Hostal Hueso

Hostal Hueso
Trujillo
United States
ALFRED
€65
includes taxes & fees
7 Oct - 8 Oct
Hostal Hueso
A stone-walled hallway with a dark door, a staircase, and a potted plant.
A sign reading "PLAZA SANDRA" on a textured wall, with a tiled pool in front.
A hotel lobby with a reception desk, a vase of flowers, a framed artwork, a lamp, and a seating area.
A spacious living area with wicker furniture, a stone wall, and a view of the outside.

9. Plaza Sandra

Plaza Sandra
Trujillo
United States
Juan
€62
includes taxes & fees
21 Oct - 22 Oct
Plaza Sandra
A bed with a wooden headboard, two pillows, a bedside lamp, and a patterned bedspread.
A plaza with historic buildings, a fountain, and parked cars.
A bedroom with two beds, each with a patterned pillow and a wooden headboard.
A wooden desk with a remote control and papers, a wooden chair, and a corner of a room.

10. Alojamientos Plaza Mayor

Alojamientos Plaza Mayor
Trujillo
United States
Adela
€34
includes taxes & fees
7 Oct - 8 Oct
Alojamientos Plaza Mayor
An outdoor dining area with tables and chairs, a white canopy, and potted plants.
A hotel room with a bed, a sofa, a desk, and a chair. There is a painting on the wall and a lamp on the desk.
A conference room with rows of chairs, a projector screen, and a speaker.
A hotel entrance with a reception desk, a potted plant, and a planter with small plants.

11. Hospedium Hotel Triana

Hospedium Hotel Triana
Miajadas
United Kingdom
tina
€84
includes taxes & fees
7 Oct - 8 Oct
Hospedium Hotel Triana
A hotel room with a large bed, two bedside tables, a nightstand, a door leading to a bathroom, and a wall-mounted light fixture.
A compact living space with a kitchenette, dining area, and a TV.
A hallway with wooden doors, a tiled floor, and a glass block wall.
A compact kitchen with wooden cabinets, a stainless steel range hood, a microwave, and a refrigerator. There is a dining table with chairs and a coffee maker.

12. Hostal Ruralis Altozano

Hostal Ruralis Altozano
Montánchez
Spain
MARCO ANTONIO
€45
includes taxes & fees
7 Oct - 8 Oct
Hostal Ruralis Altozano
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Learn more about Santa Cruz de la Sierra

Venture to Plaza Mayor and Pizarro House Museum—just two of the sights around Santa Cruz de la Sierra.

See all hotels in Santa Cruz de la Sierra
A large brick church with two bell towers and palm trees in front.

Top Santa Cruz de la Sierra Hotel Reviews

Parador de Trujillo

Parador de Trujillo

8/10 Good
"Clean room Staff very nice steak was tough Breakfast ok"
Beryl 1-night trip
Posted 7 days ago
Parador de Trujillo
Hotel Izan Trujillo

Hotel Izan Trujillo

10/10 Excellent
"Nice hotel with a secure room for cycles for those on tour like me. Nice rooms and good facilities. Restaurant is good but also great places to eat on the Plaza."
Mark 1-night trip
Posted 2 months ago
Hotel Izan Trujillo
Plaza Sandra

Plaza Sandra

10/10 Excellent
"Era un lugar limpio y acogedor, y había muchos sitios a los que se podía ir andando. El personal fue muy atento. Aparcar fue todo un reto, sobre todo cerca del mercado semanal. Pasamos una estancia muy agradable."
Alexandra 3-night trip
Posted 3 months ago
Plaza Sandra
Eurostars Palacio Santa Marta

Eurostars Palacio Santa Marta

10/10 Excellent
"We had a wonderful stay at Eurostars Palacio Santa Marta. The hotel is set inside a beautifully restored historic building just steps from Plaza Mayor, making it perfect for exploring Trujillo on foot. Our room was spacious, comfortable, and very quiet. Alba was warm, welcoming, and made everything easy. Overall, an excellent stay in a charming location — we’d happily return."
Ismael 1-night trip
Posted 4 months ago
Eurostars Palacio Santa Marta

Frequently asked questions

What's the best place to stay in Santa Cruz de la Sierra?
Hotel Izan Trujillo, located 0.1 mi (0.1 km) from the heart of Santa Cruz de la Sierra, is a top choice for your stay, based on our traveller data. Other good choices for your trip to the area are Eurostars Palacio Santa Marta and Parador de Trujillo. See all available top hotels, or vacation rentals in Santa Cruz de la Sierra.
What are some of the best holiday rentals that Santa Cruz de la Sierra has to offer?
Rural house with swimming pool El Huerto del Olivo, Plasenzuela, Trujillo, Cáceres: This holiday home rental outside of Santa Cruz de la Sierra is equipped with a BBQ, air conditioning and laundry facilities to help you feel comfortable during your stay. Kitchen amenities include a dishwasher, a stovetop and a microwave. See all vacation rentals in Santa Cruz de la Sierra.
If I need to cancel my hotel reservation in Santa Cruz de la Sierra, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you have a reservation that's non-refundable, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz de la Sierra.
What are some accommodation options with pools in Santa Cruz de la Sierra?
Hotel Izan Trujillo: Offers complimentary high-speed (wired) Internet access, a seasonal outdoor pool and LED televisions. Also, another option that offers an on-site pool is Rural house (full rental) El Olivar del Marqués for 26 people. View all hotels with pools in Santa Cruz de la Sierra.
How is it staying in Santa Cruz de la Sierra?
Those travelling to Santa Cruz de la Sierra will definitely enjoy the sights to see and things to do. In Santa Cruz de la Sierra, there are 9 hotels and other accommodation options to choose from. Find out more about Santa Cruz de la Sierra.
What should I do while I'm visiting Santa Cruz de la Sierra?
Places to visit in the wider area include Plaza Mayor, Pizarro House Museum and Trujillo Castle. You'll also find Museo de Vino y Queso and Juan Pizarro de Orellana Palace in the area. Take a look at what more there is to see and do in Expedia's Santa Cruz de la Sierra guide.
What's the seasonal weather in Santa Cruz de la Sierra?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 9°C. Average annual precipitation for Santa Cruz de la Sierra is 571 mm.

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