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Our top choices for Santa Cruz luxury hotels
1. Hotel Alfonso XIII, a Luxury Collection Hotel, Seville
Hotel Alfonso XIII, a Luxury Collection Hotel, SevilleHistorical Center
9.4 out of 10, Exceptional, (1,000 reviews)
- Timeless elegance flourishes in a historic Seville hotel steps from the Royal Alcázar.
The price is €446
includes taxes & fees
30 Nov - 1 Dec
2. EME Catedral Mercer Hotel
EME Catedral Mercer HotelHistorical Center
8.8 out of 10, Excellent, (1,001 reviews)
- Lavish retreat steps from Seville Cathedral featuring full-service spa treatments, poolside bar, and rooftop terrace with panoramic views.
The price is €198
includes taxes & fees
29 Nov - 30 Nov
3. El Rey Moro Hotel Boutique
El Rey Moro Hotel BoutiqueHistorical Center
9.4 out of 10, Exceptional, (979 reviews)
- Indulge in historic luxury steps from Royal Alcázar with deep soaking tubs, rooftop terrace views, and thoughtful boutique comforts.
The price is €137
includes taxes & fees
1 Dec - 2 Dec
4. Genteel Home Casa Pimienta
Genteel Home Casa PimientaHistorical Center
9.0 out of 10, Wonderful, (2 reviews)
5. Serras Sevilla
Serras SevillaHistorical Center
9.6 out of 10, Exceptional, (11 reviews)
The price is €345
includes taxes & fees
22 Nov - 23 Nov
6. Hotel Mercer Sevilla 5 GL
Hotel Mercer Sevilla 5 GLHistorical Center
9.8 out of 10, Exceptional, (184 reviews)
- Discover luxurious elegance in historic Seville where attentive staff, poolside relaxation, and boutique charm create an intimate escape.
The price is €342
includes taxes & fees
30 Nov - 1 Dec
7. Hotel Casa Palacio Don Ramón 5* GL by Kaizen Hoteles
Hotel Casa Palacio Don Ramón 5* GL by Kaizen HotelesHistorical Center
9.8 out of 10, Exceptional, (249 reviews)
- Discover colonial luxury in Seville's historic centre with facials, seasonal pool, and rooftop terrace just steps from iconic landmarks.
The price is €360
includes taxes & fees
1 Dec - 2 Dec
8. CoolRooms Palacio Villapanés 5 GL
CoolRooms Palacio Villapanés 5 GLHistorical Center
9.6 out of 10, Exceptional, (1,000 reviews)
- Palatial luxury awaits at this 5-star boutique hotel featuring a full-service spa, seasonal outdoor pool, and rooftop terrace in Seville.
The price is €219
includes taxes & fees
2 Dec - 3 Dec
9. Thompson Seville, by Hyatt
Thompson Seville, by HyattHistorical Center
10.0 out of 10, Exceptional, (14 reviews)
The price is €170
includes taxes & fees
16 Nov - 17 Nov
10. Hotel Colón Gran Meliá
Hotel Colón Gran MeliáHistorical Center
9.4 out of 10, Exceptional, (1,000 reviews)
- Five-star serenity awaits at this luxury Seville hotel, where rooftop pool relaxation meets spa indulgence just steps from the cathedral.
The price is €280
includes taxes & fees
1 Dec - 2 Dec
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels in Santa Cruz
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
 Hotel Alfonso XIII, a Luxury Collection Hotel, Seville | 9.4 Exceptional 1,000 reviews | View | ||||||
 Hotel Boutique Casa del Poeta Sevilla | 9.8 Exceptional 992 reviews | View | ||||||
 EME Catedral Mercer Hotel | 8.8 Excellent 1,001 reviews | View | ||||||
 Los Seises Sevilla, a Tribute Portfolio Hotel | 8.4 Very good 540 reviews | View | ||||||
 Hotel Amadeus Sevilla | 9.6 Exceptional 1,305 reviews | View |
Top Santa Cruz Hotel Reviews
EME Catedral Mercer Hotel
EME Catedral Mercer HotelHistorical Center
10/10 Excellent
Lovely hotel with gorgeous rooftop. The room was also lovely.
Anonymous traveller
