Santa Cruz Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €185 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Santa Cruz

Find the best Santa Cruz areas and neighborhoods for the activities you enjoy most. Learn more about Santa Cruz
Mexico featuring mountains and heritage elements

Downtown Querétaro

3 out of top 10 points of interest in this area

Downtown Querétaro is known for its ample dining options, and you can make a stop by Zenea Garden and Plaza de Armas while in the area.

Find hotels in Downtown Querétaro

Top hotels in Santa Cruz

Hotel Meson de Isabel

Hotel Meson de Isabel

3 out of 5
C. 5 de Mayo Querétaro QUE
7.4/10 Good! (61 reviews)
Staff very helpful with figuring out the TV. Smoke alarm needed a new battery.

Reviewed on 3 Dec 2024

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Hotel Meson de Isabel
Mesón de San Andrés

Mesón de San Andrés

3 out of 5
20 de Noviembre #37 Querétaro QUE
Fully refundableReserve now, pay when you stay
The price is €55 per night from 4 Jan to 5 Jan
€55
4 Jan - 5 Jan
includes taxes & fees
9/10 Wonderful! (115 reviews)
Nice stay!
We were very comfortable. The apartment suited our needs offering 3 bedrooms. We used all the rooms and the common areas which included roof decks with lovely views. Also well located with easy walking access to the historic center and driving access to areas around the city. The staff/ owners were ...

Reviewed on 24 Jul 2025

Mesón de San Andrés
Cinco de Mayo Hotel

Cinco de Mayo Hotel

2.5 out of 5
Calle 5 de Mayo 106 Querétaro QUE
Fully refundableReserve now, pay when you stay
The price is €27 per night from 4 Jan to 5 Jan
€27
4 Jan - 5 Jan
includes taxes & fees
7.4/10 Good! (310 reviews)
great room for the price.

Reviewed on 5 Oct 2025

Cinco de Mayo Hotel
See all 568 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Santa Cruz holiday package cost?
Explore the best of Santa Cruz from just . Choose from a wonderful selection of rental cars, hotels and flights to suit your budget. You can pick up even better deals when you add a couple of tours or activities to your package.
How do I get a cheap travel package to Santa Cruz?
Just think of all the thrilling things you could do in Santa Cruz with a wad of extra cash in your pocket. Watch your savings stack up when you combine your flights, hotels and other bookings into a Santa Cruz holiday package. You have plenty of choice when you book your trip with Expedia too. In fact, you can pick from more than 550 air carriers and 1,000,000 properties across the globe. Whether you're heading away with the family or travelling with someone special, planning a getaway to Santa Cruz is better with a package.
How far in advance should I book my Santa Cruz holiday?
Savvy travellers will likely want to book as early as possible. You can normally look up international airfares on Expedia up to a year before your flight. If you're purchasing tickets last minute, don't despair. Cheap prices sometimes occur in the last weeks prior to departure.
What does an Expedia Santa Cruz travel package include?
Hotels, car rentals and flights — we bring you the very best bargains. All you'll have to do is pick and choose your favourite combination. After you've made your booking, you can add on the exciting stuff like activities and tours. Our travel packages make it easy to craft an exciting Santa Cruz getaway.
What should I know before booking a Santa Cruz travel package?
An Expedia travel package can be customized for your circumstances and is an easy way to make your money go further. How little or much you include is your call. Rental cars, hotels and flights — mix and match whatever combination suits your style.
Can I choose my airline with a Santa Cruz Expedia holiday package?
Most definitely. Expedia has over 550 partner airlines to pick from around the globe. With such a huge range of choice, finding the right carrier to fly you to Santa Cruz will be a breeze.
If I'm not able to travel, can I cancel my Santa Cruz holiday package?
We get that sometimes life doesn't go according to plan. If you've locked in a Santa Cruz holiday package and have to cancel or amend it, we're here to help. We recommend taking a look at our Customer Service Portal first for information. But in general, if you've booked your package within 24 hours, you may be able to cancel and rebook for free. If it's more than 24 hours, your hotel, airline or car rental company may impose a charge.

Things to do

Querétaro: Tranvia Road Experience

Querétaro: Tranvia Classic Trolley Car Guided Tour

€7
per adult
80% of travellers recommend
Querétaro: Tranvia Classic Trolley Car Guided Tour
Querétaro: Electric Vehicle Tour of Historic Center

Querétaro: Electric Vehicle Tour of Historic Center

€13
per adult
Querétaro: Electric Vehicle Tour of Historic Center
Querétaro: Ecological Electric Vehicle Tour

Querétaro: Ecological Electric Vehicle Tour

€13
per adult
Querétaro: Ecological Electric Vehicle Tour
See all activities in Querétaro
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.