Default HTG hotel image

Hotel Guide - Santa Fe River hotels in , United States of America.

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
13 Nov - 15 Nov
In two weeks
20 Nov - 22 Nov

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Santa Fe River hotels

A hotel with a covered entrance, stone facade, and blue lighting accents.

1. Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
17.6 km from Santa Fe River
9.4 out of 10, Exceptional, (1,000 reviews)
"Great stay!!"
United States
Austin
The price is €107
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
A modern kitchen area with a central counter, various food stations, and a chalkboard menu.

2. Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
18 km from Santa Fe River
9.4 out of 10, Exceptional, (572 reviews)
"Great breakfast!"
United States
Pamela
The price is €111
includes taxes & fees
29 Nov - 30 Nov
Hampton Inn & Suites Alachua I-75
A stone water feature with cascading water, surrounded by a brick wall and greenery.

3. BlueGem Motel

BlueGem Motel
2.0 star property
9.6 km from Santa Fe River
9.2 out of 10, Wonderful, (486 reviews)
"Very clean rooms and homey atmosphere!"
United States
Myra
The price is €97
includes taxes & fees
8 Dec - 9 Dec
BlueGem Motel
A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.

4. Vista Verde Farm Retreat

Vista Verde Farm Retreat
2.0 star property
17.1 km from Santa Fe River
9.8 out of 10, Exceptional, (21 reviews)
"Sweet spot to stay! We will return."
United States
Stacy
The price is €182
includes taxes & fees
9 Nov - 10 Nov
Vista Verde Farm Retreat
A modern hotel room with a large bed, a flat-screen TV, a desk, and a mural of a landscape.

5. Clarion Pointe Alachua - Gainesville Area

Clarion Pointe Alachua - Gainesville Area
2.0 star property
18.7 km from Santa Fe River
8.0 out of 10, Very good, (29 reviews)
"Big beautiful pool, room was very clean, bed was super comfortable, staff was awesome!"
United States
Debra
The price is €73
includes taxes & fees
29 Nov - 30 Nov
Clarion Pointe Alachua - Gainesville Area
A hotel room with two beds, a desk, a chair, and a ceiling fan.

6. High Springs Country Inn

High Springs Country Inn
2.0 star property
9.4 km from Santa Fe River
8.4 out of 10, Very good, (59 reviews)
"Unique chance to stay in 1950's style motel."
United States
Paige
The price is €78
includes taxes & fees
19 Nov - 20 Nov
High Springs Country Inn
A hotel room with a bed, a desk, a chair, a TV, and a lamp.

7. Best Western Waldo Inn and Suites

Best Western Waldo Inn and Suites
2.5 star property
51.2 km from Santa Fe River
8.8 out of 10, Excellent, (1,002 reviews)
"Close to downtown St Augustine - about 15 mins away"
United States
Sarah
The price is €84
includes taxes & fees
19 Nov - 20 Nov
Best Western Waldo Inn and Suites
A hotel room with a bed, a desk, a chair, a refrigerator, and a microwave.

8. Palms Garden Inn

Palms Garden Inn
2.0 star property
20.3 km from Santa Fe River
7.6 out of 10, Good, (660 reviews)
"Very good place nice and quiet and clean"
United States
Igor
The price is €70
includes taxes & fees
9 Nov - 10 Nov
Palms Garden Inn
A bathroom with a granite countertop sink, a mirror, a hairdryer, a shower with yellow tiles, and a white bathtub.

9. Quality Inn Alachua - Gainesville Area

Quality Inn Alachua - Gainesville Area
2.5 star property
18.6 km from Santa Fe River
7.2 out of 10, Good, (1,001 reviews)
"The staff was very nice. Bed was comfortable."
United States
Gerald
The price is €73
includes taxes & fees
28 Nov - 29 Nov
Quality Inn Alachua - Gainesville Area
A hotel room with two beds, a desk, a chair, and a television.

10. Royal Inn

Royal Inn
2.0 star property
17.9 km from Santa Fe River
7.2 out of 10, Good, (208 reviews)
"Bugs in room"
United States
James
The price is €73
includes taxes & fees
13 Nov - 14 Nov
Royal Inn
A modern reception desk area with a blue geometric wall design, wooden accents, and a visible reception counter.

11. Holiday Inn Express Starke by IHG

Holiday Inn Express Starke by IHG
2.5 star property
56.4 km from Santa Fe River
9.6 out of 10, Exceptional, (649 reviews)
"Very clean rooms and wonderful staff."
United States
Georgia
The price is €103
includes taxes & fees
6 Dec - 7 Dec
Holiday Inn Express Starke by IHG
A hotel room with a bed, bedside lamps, a nightstand, a mirror, a bathroom with a sink and a bathtub.

12. Americas Best Value Inn Starke

Americas Best Value Inn Starke
2.0 star property
58.4 km from Santa Fe River
7.2 out of 10, Good, (590 reviews)
"Horrible place to stay if you have kids"
United States
Andy
The price is €75
includes taxes & fees
9 Nov - 10 Nov
Americas Best Value Inn Starke
A swimming pool with a white fence, palm trees, and a building with balconies in the background.

13. Motel 6 Starke, FL

Motel 6 Starke, FL
2.0 star property
58.5 km from Santa Fe River
6.0 out of 10, (784 reviews)
"Motel with clean & reasonable price! Traveled with my pet and the place was good for us! I would recommend to anyone looking for rooms on a budget that are clean and comfortable"
United States
Carol
The price is €67
includes taxes & fees
8 Dec - 9 Dec
Motel 6 Starke, FL
A room with a bed, bedside lamps, a mirror, a sink, and a dresser.

14. Travelers Inn

Travelers Inn
2.0 star property
38.8 km from Santa Fe River
6.4 out of 10, (417 reviews)
"Decent alternative"
United States
Joseph
The price is €66
includes taxes & fees
9 Nov - 10 Nov
Travelers Inn
A covered outdoor seating area with a round wooden table, white wicker chairs, and a black grill.

15. < 1 Mi From Suwannee River, Hideaway w/ Lanai

< 1 Mi From Suwannee River, Hideaway w/ Lanai
3.0 star property
23.3 km from Santa Fe River
9.0 out of 10, Wonderful, (2 reviews)
"The Air B & B was amazing. The property and the A B & B was awesone, Clean, Quiet and very comfortable. Although some nights got a bit chilly and this property only had AC no heat. We managed just fine. We left it in perfect conditions according to the directions they wanted it left in. Thank you so much and we will be renting again. We also would recommend this to others. "
United States
Karen
The price is €347
includes taxes & fees
9 Nov - 10 Nov
< 1 Mi From Suwannee River, Hideaway w/ Lanai
A compact hotel room with a kitchenette, a dining area, a sofa, and large windows.

16. Campus Inn by Hotel O Gainesville - University Area

Campus Inn by Hotel O Gainesville - University Area
2.5 star property
38.8 km from Santa Fe River
4.2 out of 10, (254 reviews)
"I would never reserve there again; it's terrible."
United States
Cristian
The price is €60
includes taxes & fees
9 Nov - 10 Nov
Campus Inn by Hotel O Gainesville - University Area
A gazebo with a tiled roof, surrounded by stone pillars and palm trees.

17. Best Western Starke

Best Western Starke
2.5 star property
58.7 km from Santa Fe River
8.6 out of 10, Excellent, (755 reviews)
"Great place to stay"
United States
Lonnie
The price is €89
includes taxes & fees
2 Dec - 3 Dec
Best Western Starke
A clear blue swimming pool with a metal safety fence, surrounded by a building with multiple windows and balconies.

18. Red Carpet Inn

Red Carpet Inn
2.0 star property
58.3 km from Santa Fe River
8.6 out of 10, Excellent, (664 reviews)
"Very nice remodel old style motel,looks like new inside and outside"
United States
david
The price is €69
includes taxes & fees
9 Nov - 10 Nov
Red Carpet Inn
A hotel room with a large bed, two bedside tables, a nightstand, a painting on the wall, and a window with a curtain.

19. Americas Best Value Inn Alachua

Americas Best Value Inn Alachua
2.0 star property
17.9 km from Santa Fe River
5.0 out of 10, (630 reviews)
"It was a place to stay"
United States
Jennifer
Americas Best Value Inn Alachua
A kitchen with a sink, a microwave, and cabinets.

20. The Humming Bird Suite - Affordable Lakefront Fun

The Humming Bird Suite - Affordable Lakefront Fun
3.0 star property
63.2 km from Santa Fe River
The price is €110
includes taxes & fees
12 Nov - 13 Nov
The Humming Bird Suite - Affordable Lakefront Fun
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to Santa Fe River

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A hotel with a covered entrance, stone facade, and blue lighting accents.
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
9.4
Exceptional
1,000 reviews
View
A modern kitchen area with a central counter, various food stations, and a chalkboard menu.
Hampton Inn & Suites Alachua I-75
2.5 star property
9.4
Exceptional
572 reviews
View
A stone water feature with cascading water, surrounded by a brick wall and greenery.
BlueGem Motel
2.0 star property
9.2
Wonderful
486 reviews
View
A modern kitchen with a flat-screen TV, a microwave, and a coffee maker on a wooden cabinet. There is a window with a view of a green landscape.
Vista Verde Farm Retreat
2.0 star property
9.8
Exceptional
21 reviews
View
A modern hotel room with a large bed, a flat-screen TV, a desk, and a mural of a landscape.
Clarion Pointe Alachua - Gainesville Area
2.0 star property
8.0
Very good
29 reviews
View

Top Santa Fe River Hotel Reviews

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

10/10 Excellent
"Cabins is a peaceful and relaxing place, perfect for anyone looking to escape the busy city life and reconnect with nature. It’s a great spot to unwind, clear your mind, and enjoy some quiet time surrounded by nature. A wonderful getaway to relax and recharge!"
Humberto 2-night trip
Posted 9 hours ago
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Other attractions near Santa Fe River

An underwater scene with rocky formations and clear water.

Ginnie Spring

8.6/10 (51 reviews)
Commune with nature and explore the great outdoors at Ginnie Spring during your travels in High Springs. Amble around the area's parks or visit its shops.
See properties

Frequently asked questions

What's the area like around Santa Fe River?
If you're planning to come to the area to visit Santa Fe River, take some time to see the rest of the sights while you're in town. This family-friendly area is known for its array of dining options and sporting events. You'll find 31 hotels and other accommodations within a few miles for a convenient home base.
What's the best place to stay near Santa Fe River?
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy is one of the top choices for your stay based on our traveller data, and this cabin offers free parking and private patios. You'll find it 5.2 mi (8.3 km) from Santa Fe River. Other good options in the area include Holiday Inn Express & Suites Alachua - Gainesville Area by IHG and BlueGem Motel.
How many hotels can I expect to find close to Santa Fe River?
Expedia has 31 hotels and other accommodation options a few miles from Santa Fe River.
If I need to cancel the hotel reservation for my stay near Santa Fe River, will I receive a refund?
Yes, you'll find most room reservations are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within a 24-hour period of booking. Add your dates and click on "Search", then filter by "fully refundable" to get top deals close to Santa Fe River.