Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Santee Hotel Guide - Family Friendly Hotels in Santee, South Carolina

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Check availability on Santee Family Friendly Hotels

Tonight
29 Aug - 30 Aug
Tomorrow
30 Aug - 31 Aug
Next weekend
4 Sept - 6 Sept
In two weeks
11 Sept - 13 Sept

Our top choices for Santee family-friendly hotels

A patio area with wicker furniture, a stone fire pit, and outdoor seating.
A modern restaurant with a central island, multiple seating areas, and a large window providing natural light.
A reception desk with a wooden panel wall and a circular decorative piece above it.
A modern living room with a stone wall, a flat-screen TV, a fireplace, and a dining area with a round table and chairs.

1. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
  • A family escape that offers vibrant pool days, premium entertainment, and free breakfast just minutes from Santee State Park.
€124
includes taxes & fees
15 Sept - 16 Sept
Fairfield Inn & Suites by Marriott Santee
A hotel entrance with a sign reading "Best Western PLISS."
A modern kitchen with a red accent wall, white cabinetry, and a built-in espresso machine.
A spacious kitchen with white cabinets, a dining area with red patterned chairs, and a fireplace.
A hotel room with two large beds, a wooden headboard, bedside tables with lamps, a wardrobe, and a view of the outdoors through a window.

2. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
  • Family holiday paradise with an outdoor pool, fitness centre, and quiet, pet-friendly atmosphere for your whole family.
€105
includes taxes & fees
6 Sept - 7 Sept
Best Western Plus Santee Inn
A swimming pool with a 5 ft depth marker, surrounded by lounge chairs and a building with multiple windows.
A bathroom with a dark granite countertop, a white sink, a large mirror, a toilet, and a shower with a glass door.
A spacious lobby with a modern staircase, seating area with orange and teal chairs, and a fireplace.
A modern living room with a sofa, a red ottoman, a TV mounted on the wall, and a wooden entertainment unit.

3. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
  • Family-friendly escape at Santee with seasonal outdoor pool, free breakfast, and steps from the state park.
€97
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn & Suites Santee
A hotel room with two beds, a desk, a mirror, and a wall-mounted TV.
A small, enclosed bathroom with a shower, grab bars, and a towel rack.
A motel with a brick facade, a covered entrance, and a satellite dish.
A kitchen with a countertop, cabinets, a microwave, and a sink.

4. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
€61
includes taxes & fees
30 Aug - 31 Aug
Travelodge by Wyndham Santee
A hotel room with two beds, a desk, a chair, a lamp, and a window with curtains.
A bathroom with a sink, mirror, and a shower area.
A building with a red roof, a yellow door, and a brick facade.
A hotel room with two beds, a desk, a chair, a lamp, and a bathroom with a mirror and sink.

5. Econo Lodge Santee

Econo Lodge Santee
Santee
Econo Lodge Santee
A clean, well-lit dining area with round tables and chairs, a kitchen in the background, and a decorative leaf on the wall.
A reception desk with a clock, framed certificates, and a window with a view.
A two-story building with a sign reading "PachTree Inn".
A bathroom with a bathtub, toilet, and a shower curtain.

6. Peach Tree Inn

Peach Tree Inn
St. George
€68
includes taxes & fees
30 Aug - 31 Aug
Peach Tree Inn
A Red Roof Inn with two red leather armchairs and a small wooden table in front of a stone-patterned wall.
A two-story building with a grey facade, large windows, and a covered entrance area.
A bathroom with a bathtub, toilet, and a shower area.
A Red Roof Inn sign, a Waffle House sign, and a BP gas station.

7. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
Orangeburg
€56
includes taxes & fees
6 Sept - 7 Sept
Red Roof Inn Orangeburg
A spacious lobby with a sofa, chairs, a coffee table, and a staircase with a green leaf-patterned wall.
A reception area with a staircase, reception desk, and seating area with blue sofas.
A swimming pool with lounge chairs and umbrellas, surrounded by a building with a modern design.
A dining area with wooden tables and chairs, a large window with a view, a flat-screen TV, and a vending machine.

8. Sleep Inn Orangeburg

Sleep Inn Orangeburg
Orangeburg
€86
includes taxes & fees
4 Sept - 5 Sept
Sleep Inn Orangeburg
A backyard with a wooden deck, grill, and outdoor seating area.
A kitchen with white cabinets, a black countertop, a stainless steel stove, and a refrigerator.
A kitchen with white cabinets, a wooden dining table, and a blue accent wall.
A single-story mobile home with a covered porch and a small deck, surrounded by a well-maintained lawn and tall trees.

9. Country living lake style near Santee

Country living lake style near Santee
Summerton
€187
includes taxes & fees
29 Sept - 30 Sept
Country living lake style near Santee
A breakfast bar with pastries, fruits, and a vase with flowers.
A Travelodge motel with a parking lot and a signboard.
A hotel bathroom with a sink, mirror, hairdryer, and shower.
A hotel room with two beds, a nightstand, and two wall-mounted lamps.

10. Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
Orangeburg
€76
includes taxes & fees
30 Aug - 31 Aug
Travelodge by Wyndham Orangeburg
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Choose what matters most at family-friendly hotels in Santee

Breakfast included
Pool
All-inclusive
4 stars
5 stars

Top Santee Hotel Reviews

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

10/10 Excellent
"Love the location very friendly and clean. I love they have high security on site"
fern 1-night trip
Posted 1 hour ago
Travelodge by Wyndham Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"The room was exceptional, the breakfast was great, the staff was very friendly great Customer Service! Will be returning!"
Noelia 1-night trip
Posted 23 hours ago
Hampton Inn Santee-I-95
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Clean room"
Mohammad 2-night trip
Posted 3 days ago
Comfort Inn & Suites Santee
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The price rate was great"
Stevenson 3-night trip
Posted 2 weeks ago
Ramada by Wyndham Santee I-95

Frequently asked questions

What's Santee like for family-friendly holidays?
The welcoming destination of Santee is a great choice if you've been thinking about a holiday with the children. The excursions, lake views and golf are just a few things that make this an attractive holiday destination for families. Arrange a flight into Columbia, SC (CAE-Columbia Metropolitan), which is located 49 mi (78.8 km) from the city centre.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your family trip.
When's the best time to book a family-friendly holiday in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.
What's there to see and do with your family in Santee?
While you and the family are holidaying in Santee, you may want to explore some of the attractions here such as Orangeburg County Library Mentor Branch, Lake Marion and Edisto Memorial Gardens. Make sure that you have lots of time for activities such as Congaree National Park and Santee National Wildlife Refuge.