Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

Santee Hotels

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Tonight
28 Aug - 29 Aug
Tomorrow
29 Aug - 30 Aug
This weekend
28 Aug - 30 Aug
Next weekend
4 Sept - 6 Sept

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Our top choices for Santee hotels

1. Tru By Hilton Santee

Tru By Hilton Santee
Santee
United States
Vicky L
€93
includes taxes & fees
13 Sept - 14 Sept
Tru By Hilton Santee

2. Baymont by Wyndham Santee

Baymont by Wyndham Santee
Santee
United States
Yomerys
€71
includes taxes & fees
30 Aug - 31 Aug
Baymont by Wyndham Santee

3. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
Santee
United States
Cameron
€117
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn Santee-I-95

4. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee
United States
Melissa
€123
includes taxes & fees
15 Sept - 16 Sept
Fairfield Inn & Suites by Marriott Santee

5. Best Western Plus Santee Inn

Best Western Plus Santee Inn
Santee
United States
Bonnie
€105
includes taxes & fees
6 Sept - 7 Sept
Best Western Plus Santee Inn

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
Santee
United States
Dennis
€98
includes taxes & fees
27 Sept - 28 Sept
Holiday Inn Santee by IHG

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
Santee
United States
santa
€96
includes taxes & fees
20 Sept - 21 Sept
Comfort Inn & Suites Santee

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
Santee
United States
Mark
€61
includes taxes & fees
10 Sept - 11 Sept
Travelodge by Wyndham Santee

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
Santee
United States
William
€61
includes taxes & fees
3 Sept - 4 Sept
Super 8 by Wyndham Santee/I-95

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
Santee
United States
Clara
€57
includes taxes & fees
17 Sept - 18 Sept
Quality Inn & Suites Santee I-95

11. Red Roof Inn Santee

Red Roof Inn Santee
Santee
United States
Tiffany
€60
includes taxes & fees
1 Sept - 2 Sept
Red Roof Inn Santee

12. Econo Lodge Santee

Econo Lodge Santee
Santee
United States
Dorothy
€64
includes taxes & fees
10 Sept - 11 Sept
Econo Lodge Santee

13. Bells Marina & Resort

Bells Marina & Resort
Eutawville
United States
Amber
€67
includes taxes & fees
31 Aug - 1 Sept
Bells Marina & Resort

14. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
Orangeburg
United States
Percy
€96
includes taxes & fees
30 Aug - 31 Aug
Fairfield Inn by Marriott Orangeburg

15. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
Orangeburg
Canada
Andrew
€109
includes taxes & fees
10 Sept - 11 Sept
Tru by Hilton Orangeburg

16. SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
Manning
United States
Deland
€88
includes taxes & fees
6 Sept - 7 Sept
SureStay Hotel by Best Western Manning

17. Hampton Inn Manning

Hampton Inn Manning
Manning
United States
Parvin Brittany
€113
includes taxes & fees
7 Sept - 8 Sept
Hampton Inn Manning

18. Red Roof Inn Orangeburg

Red Roof Inn Orangeburg
Orangeburg
United States
Amanda
€56
includes taxes & fees
3 Sept - 4 Sept
Red Roof Inn Orangeburg

19. Peach Tree Inn

Peach Tree Inn
St. George
United States
Linda
€68
includes taxes & fees
29 Aug - 30 Aug
Peach Tree Inn

20. Southern Lodge 601

Southern Lodge 601
Orangeburg
United States
Martin
€73
includes taxes & fees
23 Sept - 24 Sept
Southern Lodge 601
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Stay near popular Santee attractions

Santee State Park

8.0/10 (219 reviews)
Perched on Lake Marion's shores, Santee State Park offers unique rondette cabins built over water. Hike through cypress swamps and sinkholes while spotting alligators, fox squirrels, and diverse birdlife.
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Santee Cooper Country Club

7.8/10 (94 reviews)
This George Cobb-designed course winds through majestic pines with strategic doglegs and panoramic Lake Marion views. Enjoy the signature closing hole and well-maintained fairways perfect for golfers of all skill levels.
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Santee National Golf Club

8.0/10 (74 reviews)
This championship course blends Lowcountry charm with highland terrain, featuring moss-draped oaks and pristine bunkers. Enjoy diverse play with wide-open front nine and wooded back nine challenges.
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Santee Town Hall

Santee Town Hall serves as the community's administrative hub with rental spaces for local events. The grounds feature a charming gazebo and spacious lawn perfect for seasonal celebrations like the Easter Egg Hunt.
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Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

See all hotels in Santee
A tree with Spanish moss and autumn leaves in a body of water.

Top Santee Hotel Reviews

Tru By Hilton Santee

Tru By Hilton Santee

10/10 Excellent
"Clean facilities and friendly staff."
Mary 1-night trip
Posted 12 hours ago
Tru By Hilton Santee
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

10/10 Excellent
"Clean room"
Mohammad 2-night trip
Posted 2 days ago
Comfort Inn & Suites Santee
Hampton Inn Santee-I-95

Hampton Inn Santee-I-95

10/10 Excellent
"Excellent"
Andrew 1-night trip
Posted 5 days ago
Hampton Inn Santee-I-95
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

8/10 Good
"The staff was very helpful and respectful."
Mark 4-night trip
Posted 9 days ago
Travelodge by Wyndham Santee
Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95

8/10 Good
"The price rate was great"
Stevenson 3-night trip
Posted 2 weeks ago
Ramada by Wyndham Santee I-95
Waterfront Lake Marion Retreat • Pool • Gazebo • Minutes from I-95

Waterfront Lake Marion Retreat • Pool • Gazebo • Minutes from I-95

10/10 Excellent
"The picture show washer and dryer but there wasn’t one"
Jermaine A. 2-night trip
Posted 3 weeks ago
Waterfront Lake Marion Retreat • Pool • Gazebo • Minutes from I-95
Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation

Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation

10/10 Excellent
"The condo is beautiful and clean, the location is perfect, right on the lake. The host had everything you need and all the things you could have possibly forgot. We really enjoyed our stay and would 1000% stay again. Thank you for sharing your condo with us!"
Stephanie D. 2-night trip
Posted 1 month ago
Lakefront Retreat on Lake Marion – Perfect for Fishing & Relaxation
Patio + Pool Table: Lake Marion Getaway

Patio + Pool Table: Lake Marion Getaway

10/10 Excellent
"Everyone was very responsive. When we arrived there was some garbage that a previous guest left in the wrong area. I messaged the local host and they responded immediately and had someone over the next morning first thing to take care of it. Great property!!!"
Amanda N. 7-night trip
Posted 1 month ago
Patio + Pool Table: Lake Marion Getaway
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

10/10 Excellent
"The place was as advertised very clean , and Mike was a great host, very knowledgeable and great communicator throughout the whole experience."
Deloris 2-night trip
Posted 2 months ago
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

More cheap stays in Santee

Super 8 by Wyndham, Orangeburg

Super 8 by Wyndham, Orangeburg

3608 Saint Matthews Rd Orangeburg SC
€55
1 Sept - 2 Sept
includes taxes & fees
Super 8 by Wyndham, Orangeburg
Baymont by Wyndham Santee

Baymont by Wyndham Santee

249 Britain Street Santee SC
€71
30 Aug - 31 Aug
includes taxes & fees
8/10 Very good! (1,481 reviews)
Baymont by Wyndham Santee
Tru By Hilton Santee

Tru By Hilton Santee

263 Britain St. and 273 Britain St. Santee SC
€93
13 Sept - 14 Sept
includes taxes & fees
9.2/10 Wonderful! (931 reviews)
Tru By Hilton Santee
Spark by Hilton Orangeburg

Spark by Hilton Orangeburg

731 Citadel Road Orangeburg SC
€93
30 Aug - 31 Aug
includes taxes & fees
Spark by Hilton Orangeburg
Best Western Plus Santee Inn

Best Western Plus Santee Inn

I 95 Exit 98 Santee SC
€105
6 Sept - 7 Sept
includes taxes & fees
Best Western Plus Santee Inn
Tru by Hilton Orangeburg

Tru by Hilton Orangeburg

739 Citadel Road Orangeburg SC
€109
10 Sept - 11 Sept
includes taxes & fees
Tru by Hilton Orangeburg

Find out more about Santee

Top reasons to visit Santee

  • Stunning Natural Scenery: Santee features breathtaking landscapes, including national parks, serene lakes, and charming islands, perfect for outdoor enthusiasts.
  • Recreational Activities: Enjoy a variety of activities at Santee Sportsplex, including golf, tennis, and hiking opportunities.
  • Charming Accommodation: Santee offers a range of lodging options, from cosy motels to well-appointed hotels, catering to all traveller needs.
  • Warm Hospitality: The friendly atmosphere in Santee ensures a welcoming experience for families and solo travellers alike.
  • Day Trip Opportunities: Explore nearby cities and neighbourhoods, providing additional adventures and budget-friendly options.

Find great hotels in and around Santee

In Santee, South Carolina, you'll discover a variety of accommodation options, from charming motels to well-appointed hotels, catering to diverse needs. Whether you're seeking a pet-friendly environment, a business-ready stay, or an inclusive atmosphere for LGBTQIA travellers, Santee's hotels offer a welcoming experience. Notable options include the Hilton Santee and Santee Inn, ensuring you find the perfect base for your explorations in this picturesque area.

  • Fairfield Inn & Suites by Marriott Santee: This budget-friendly hotel boasts an impressive guest rating of 9.8 out of 10, making it a top choice for families and pet owners. Located in Santee, the hotel focuses on providing a welcoming atmosphere with essential amenities for children, including cribs and highchairs. The pet-friendly policy includes a designated dog exercise area and various fees applicable for pets, ensuring a comfortable stay for both guests and their furry companions.
  • Starlight Stays: Situated 25.7km away from Santee, Starlight Stays offers a cozy and budget-friendly lodging option with a solid guest rating of 8.0 out of 10. This property features multiple entertainment options, including digital televisions in each room, perfect for unwinding after a day of exploration. The hotel's inviting atmosphere and convenient location make it an appealing choice for visitors seeking a relaxed retreat.
  • Baymont by Wyndham Santee: A suitable option for business travellers and pet owners alike, Baymont by Wyndham Santee combines comfort with convenience. The hotel’s pet policy permits dogs and cats, with specific fees and restrictions in place. Guests can expect a range of amenities tailored to business needs, alongside a warm atmosphere that caters to all types of stays. Its strategic location in Santee makes it an ideal base for exploring the surrounding area.

Where to stay near Santee

Santee, South Carolina, is a delightful destination for those seeking outdoor adventures and romantic getaways. With its friendly atmosphere, visitors can enjoy a variety of excursions suitable for families and solo travellers alike. Nearby cities and neighbourhoods offer a budget-friendly vibe, ensuring a comfortable holiday experience. Whether you're exploring the scenic landscapes or indulging in local charm, Santee promises an unforgettable time filled with warmth and hospitality.

  • Vance: Located a mere 8.0km from Santee, Vance is a charming city renowned for its picturesque landscapes and outdoor activities. With seasonal peaks in visitor numbers occurring between March to April and July, this destination is perfect for those seeking a romantic getaway or scenic adventures. Visitors can enjoy the local recreational areas and golf courses, while nearby attractions such as the tranquil lake, national state park, and beach add to the charm. Vance offers an idyllic escape for nature enthusiasts and couples alike, making it a delightful stop on your travels.
  • Potato Creek: Situated 19.3km from Santee, Potato Creek welcomes travellers year-round, with notable peaks in March to April and July. This area is celebrated for its outdoor experiences and romantic scenery, attracting visitors who appreciate nature's beauty. Popular activities include golfing and exploring the local recreational areas, while nearby landmarks such as the lake, water feature, and charming island create a perfect backdrop for relaxation and exploration. Potato Creek is an excellent choice for those looking to immerse themselves in the tranquillity of the great outdoors.
  • Summerton: Just 17.7km from Santee, Summerton is a captivating city that draws visitors throughout the year, particularly during the peak months of March to April and July. Known for its abundant outdoor opportunities and scenic views, it offers a romantic setting for couples and nature lovers. Enjoy recreational activities and golf at local venues, while the nearby lake, national state park, and island provide stunning natural attractions. Summerton is a lovely destination that promises a peaceful and rejuvenating experience for all who visit.

Things to do in Santee

Shopping

Santee offers charming local shops like Santee Antique Mall for unique finds. If you're up for a drive, visit the nearby Orangeburg Mall, which features various retail stores and dining options to enhance your shopping experience.

Recreation

Explore the serene surroundings at Santee State Park, where you can indulge in nature walks and fishing. Visit the local wellness centres for rejuvenating spa treatments, yoga sessions, and meditation classes, allowing you to unwind and reconnect with your inner self amidst tranquil landscapes.

Adventure

Santee State Park offers a thrilling array of outdoor activities, including hiking trails with stunning views and opportunities for birdwatching. Explore the serene waters of Lake Marion with kayaking or fishing, or enjoy a peaceful picnic surrounded by nature's beauty in this picturesque setting.

Nightlife

The nightlife in Santee offers a blend of relaxation and fun. Enjoy a laid-back evening at local bars like the Santee Cooper Resort's lounge, or try your luck at the nearby casinos for a vibrant atmosphere. Live music events also pop up, adding to the charm of the night.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Find the best attractions near Santee

Santee, South Carolina, is perfect for outdoor and romantic getaways, featuring stunning national parks, serene lakes, and charming islands. Visitors can explore Santee State Park, enjoy recreational activities at Santee Sportsplex, and admire nature at Santee Boulders and Santee Lakes. These attractions offer a delightful blend of adventure, culture, and scenic beauty, making Santee an ideal destination for travellers seeking a memorable experience.

  • Taw Caw Creek: Located 14.5km from Santee, this picturesque lake offers beautiful beaches and scenic views, ideal for those seeking a romantic outdoor experience. Enjoy leisurely strolls along the shore or partake in various water activities amidst tranquil surroundings.
  • Santee Indian Mound and Fort Watson Site: Situated 6.4km from Santee, this historic site exudes cultural significance, showcasing the rich history of the area. Visitors can explore the ancient mound and learn about the indigenous heritage, providing a fascinating glimpse into the past.
  • Goat Island: Also 14.5km from Santee, this charming island features lovely beaches and outdoor spaces. It’s a great spot for picnicking, hiking, or simply unwinding while enjoying the natural beauty of the surroundings.

Best time to go to Santee

The best time to visit Santee is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are average and weather is mostly sunny with light rain.

calendar iconCalendar Monthtemperature iconTemperaturerain iconPrecipitationmostly cloudy iconCloudinessoccupation rate iconOccupancyprice iconPricing
January47.3°F (8.5°C)Light RainMostly SunnyAverageSlightly Low
February51.4°F (10.8°C)Light RainMostly SunnyAverageSlightly Low
March56.8°F (13.8°C)Light RainMostly SunnySlightly HighAverage
April64.4°F (18.0°C)Light RainMostly SunnySlightly HighSlightly High
May72.0°F (22.2°C)Light RainMostly SunnyAverageSlightly High
June78.6°F (25.9°C)Light RainMostly SunnyAverageAverage
July81.5°F (27.5°C)Light RainMostly SunnySlightly HighAverage
August79.9°F (26.6°C)Light RainMostly SunnyAverageAverage
September75.4°F (24.1°C)Light RainMostly SunnyAverageAverage
October66.4°F (19.1°C)Light RainMostly SunnySlightly LowSlightly High
November56.1°F (13.4°C)Light RainMostly SunnySlightly LowAverage
December51.3°F (10.7°C)Light RainMostly SunnySlightly LowSlightly Low

The nearest major airports for your trip to Santee

Flying into Santee, South Carolina, can be easily managed via three major airports. Charleston International Airport (CHS) is situated 78.9km away, with excellent hotels like The Beach Club at Charleston Harbor Resort and Marina, Market Pavilion Hotel, and Harborside at Charleston Harbor Resort, all approximately 16.1km from the airport. Columbia Metropolitan Airport (CAE) is also 78.9km away, and nearby accommodations include Fairfield by Marriott Inn & Suites, Executive Inn, and Days Inn by Wyndham, located between 4 and 11.3km from the airport. Myrtle Beach International Airport (MYR), 144.8km distant, offers options such as DoubleTree Resort by Hilton, Sheraton Myrtle Beach, and Marina Inn At Grande Dunes, with distances ranging from 2 to 12.9km.

Frequently asked questions

Where is the best place for a stay in Santee?
Based on our traveller data, Baymont by Wyndham Santee is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your visit include Tru By Hilton Santee and Fairfield Inn & Suites by Marriott Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best holiday rentals that Santee has to offer?
Patio + Pool Table: Lake Marion Getaway: This highly rated holiday home rental in Santee is located on a lake, and has a patio, a garden and air conditioning to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. You and your friends and family can relax into your holiday with amenities such as a selection of games. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What's the best place to stay on a budget in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Santee.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your stay with the kids. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are two other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best dog-friendly hotel in Santee?
Baymont by Wyndham Santee is a top hotel for people travelling with their pets, and offers concierge services and free WiFi for its human guests. Two other good options for you and your pet include Tru By Hilton Santee and Fairfield Inn & Suites by Marriott Santee. See more pet-friendly hotel accommodations in Santee.
What's the best accommodation for a golf trip to Santee?
Ramada by Wyndham Santee I-95 is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Holiday Inn Santee by IHG and Super 8 by Wyndham Santee/I-95. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodation options with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast and free WiFi. Quality Inn & Suites Santee I-95 is an additional hotel with an on-site pool. View all hotels with pools in Santee.
What is staying in Santee like?
Families will find child-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and cafes. In Santee, there are 151 hotels and other accommodation options to choose from. Find out more about Santee.
What are the top places to visit in Santee?
Favourite places to visit include Santee Cooper Country Club, Santee State Park and Lake Marion. A couple of additional sights to add to your itinerary are Santee National Golf Club and Santee Town Hall. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.

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