
Santee Hotels
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Santee
Pet friendly
Cabin
Check prices for these dates
Our top choices for Santee hotels

Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (675 reviews)
The price is €102
includes taxes & fees
9 Feb - 10 Feb

Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,003 reviews)
The price is €115
includes taxes & fees
20 Jan - 21 Jan

Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,434 reviews)
The price is €71
includes taxes & fees
22 Jan - 23 Jan

Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,003 reviews)
The price is €123
includes taxes & fees
25 Jan - 26 Jan

Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,003 reviews)
The price is €112
includes taxes & fees
20 Jan - 21 Jan

Holiday Inn Santee by IHG
Holiday Inn Santee by IHGSantee
8.2 out of 10, Very good, (986 reviews)
The price is €107
includes taxes & fees
8 Feb - 9 Feb

Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
8.0 out of 10, Very good, (1,002 reviews)
The price is €98
includes taxes & fees
14 Jan - 15 Jan

Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
7.0 out of 10, Good, (687 reviews)
The price is €53
includes taxes & fees
14 Jan - 15 Jan

Red Roof Inn Santee
Red Roof Inn SanteeSantee
6.6 out of 10, (642 reviews)
The price is €67
includes taxes & fees
11 Feb - 12 Feb

Super 8 by Wyndham Santee
Super 8 by Wyndham SanteeSantee
6.8 out of 10, (441 reviews)
The price is €71
includes taxes & fees
26 Jan - 27 Jan

Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
6.0 out of 10, (464 reviews)
The price is €57
includes taxes & fees
20 Jan - 21 Jan

Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95Santee
6.4 out of 10, (548 reviews)
The price is €58
includes taxes & fees
20 Jan - 21 Jan

Econo Lodge Santee
Econo Lodge SanteeSantee
6.4 out of 10, (310 reviews)
The price is €60
includes taxes & fees
27 Jan - 28 Jan

Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,007 reviews)
The price is €101
includes taxes & fees
28 Jan - 29 Jan

Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
8.4 out of 10, Very good, (709 reviews)
The price is €80
includes taxes & fees
10 Feb - 11 Feb

Hampton Inn & Suites Orangeburg
Hampton Inn & Suites OrangeburgOrangeburg
9.4 out of 10, Exceptional, (769 reviews)
The price is €108
includes taxes & fees
8 Feb - 9 Feb

SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western ManningManning
8.6 out of 10, Excellent, (1,003 reviews)
The price is €85
includes taxes & fees
1 Feb - 2 Feb

Spark by Hilton Orangeburg
Spark by Hilton OrangeburgOrangeburg
7.8 out of 10, Good, (1,005 reviews)
The price is €83
includes taxes & fees
8 Feb - 9 Feb

SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott OrangeburgOrangeburg
8.8 out of 10, Excellent, (685 reviews)
The price is €108
includes taxes & fees
19 Jan - 20 Jan

Holiday Inn Express & Suites Orangeburg by IHG
Holiday Inn Express & Suites Orangeburg by IHGOrangeburg
8.6 out of 10, Excellent, (797 reviews)
The price is €125
includes taxes & fees
2 Feb - 3 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Santee attractions
Learn more about Santee
Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

More cheap stays in Santee

Baymont by Wyndham Orangeburg North
3583 Saint Matthews Rd Orangeburg SC
The price is €53 per night from 19 Jan to 20 Jan
€53
19 Jan - 20 Jan
includes taxes & fees
5.8/10 (1,001 reviews)
Frequently asked questions
Explore a world of travel with Expedia
- 3 Star Hotels in Holly Hill
- Alcolu Hotels
- Arthurtown Hotels
- Bamberg Hotels
- Branchville Hotels
- Brookdale Hotels
- Casino Hotels in Coastal South Carolina
- Denmark Hotels
- Gaston Hotels
- Goose Creek Hotels
- Holly Hill Hotels
- Kingstree Hotels
- Apartments in Ladson
- Ladson Hotels
- Hotels near Lake Marion
- Pet Friendly Hotels in Manning
- Manning Hotels
- Moncks Corner Hotels
- Orangeburg Hotels
- Pinopolis Hotels
- Round O Hotels
- Saint Matthews Hotels
- Salters Hotels
- Hotels near Shaw Air Force Base
- St. George Hotels
- Stilton Hotels
- Hotels with Air Conditioning in Summerton
- Summerton Hotels
- Apartments in Summerville
- B&B in Summerville
- Caravan Parks in Summerville
- Cottages in Summerville
- Guest Houses in Summerville
- Summerville Historic District Hotels
- Beach Hotels in Summerville
- Extended Stay America Hotels in Summerville
- La Quinta Inn & Suites Hotels in Summerville
- Summerville Hotels
- Luxury Hotels in Sumter
- Sumter Hotels
- Hotels near Three Rivers Greenway
- Hotels with Connecting Rooms in Walterboro
- Walterboro Hotels
- Woodrow Hotels
- Flights to Bamberg
- Flights to Moncks Corner
- Flights to Orangeburg
- Flights to Salters
- Flights to Summerville
- Flights to Sumter
- Flights to Walterboro
- Flights from Salters
- Flights from Canadys
- Flights from Round O
- Flights from Saint Matthews
- Flights from Pinewood
- Flights from Woodrow
- Flights from Berkeley County
- Azalea Park
- Cades Holidays
- Visit Canadys
- Congaree National Park
- Cope Holidays
- Visit Cope
- Dalzell Holidays
- Visit Dalzell
- Visit Eutawville
- I.p. Stanback Museum & Planetarium
- James Allen Park
- Visit Kingstree
- Orangeburg Holidays
- Visit Pineville
- Round O Holidays
- Santee National Wildlife Refuge
- Santee State Park
- Visit Smoaks
- Visit Summerton
- Visit Summerville
- Sumter Mall
- Sumter Holidays
- Visit Turbeville
- Vance Holidays
- Visit Vance
- White Gables
- Addcar rental Rental Cars in Coastal South Carolina
- Budget Rental Cars in Coastal South Carolina
- Car hire Denmark
- Car hire Manning
- Car hire Summerville
- Discount Car Rentals Rental Cars in Coastal South Carolina
- Midway Car Rental Rental Cars in Coastal South Carolina
- Midway Car Rental Rental Cars in Walterboro - St. George
- Movida Rent A Car Rental Cars in Summerville
- Priceless Car Rental Rental Cars in Coastal South Carolina
- Surprice Car Rentals Rental Cars in Coastal South Carolina
- Car hire in Thrifty Car Rental 460 York Street
- Thrifty Car Rental Rental Cars in Coastal South Carolina










































































