Santee Hotels

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    today icon
    Change your mind
    Book hotels with free cancellation

Check Santee hotel prices

Tomorrow night
This weekend
Next weekend

Filter by

Popular filters
Popular filters
Total price
Guest rating
Guest rating
Property class
Payment type
Payment type
Property type
Property type
Area
Area
Popular locations
Popular locations
Meal plans available
Meal plans available
Amenities
Amenities
Accessibility
Accessibility
Traveller experience
Traveller experience

Top 10 trending Santee hotels

Property grounds
Spacious, Scenic Wagner Haven w/ River Access
10.0 out of 10, Exceptional, (19)
"The house was over the top perfect for our family. It was spacious, everyone had their own space when they needed it. The kitchen/dining area was large enough for everyone to be in the kitchen at the same time helping cook. The property is near a river and the hike there and back was just what we needed for a workout. Golf cart was available to quick trips to the river. Peaceful and quiet surroundings. Already have reservations for next year"
Spacious, Scenic Wagner Haven w/ River Access
Beach
The Copper Lodge in Springfield
10.0 out of 10, Exceptional, (19)
"Extremely clean. Nice and quiet. All the amenities you could want."
The Copper Lodge in Springfield
Fridge, microwave, oven, stovetop
Bear Historic Home
10.0 out of 10, Exceptional, (32)
"Beautiful historical home. Enough room for everyone. Would definitely recommend. Having lived in the area previously we found more than enough things to do.."
Bear Historic Home
Save an average of 15% on thousands of hotels when you're signed in
3 bedrooms
Private updated hunting lodge/farmhouse
10.0 out of 10, Exceptional, (1)
"Great place!!"
Private updated hunting lodge/farmhouse
Property grounds
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
10.0 out of 10, Exceptional, (44)
"Beautiful place and a great view of the river. We will most likely be back next year"
Overlooks Lewis & Clark Lake/Missouri River Basin-3 Hours Northwest of Omaha
Property grounds
Cottage on Verdigris Creek
9.8 out of 10, Exceptional, (6)
"This property is in a great location! It is clean and well stocked with the essentials! The check in and communication was great! I would stay there again."
Cottage on Verdigris Creek
Microwave, dishwasher, coffee/tea maker, cookware/dishes/utensils
Running Water Lodge with great amenities
Running Water Lodge with great amenities
Private kitchen
On the Bluff, Overlooking the River. Outdoorsman’s Paradise!
On the Bluff, Overlooking the River. Outdoorsman’s Paradise!
Don't see what you're looking for?
See all available properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

More cheap stays in Santee

Lewis and Clark Resort

Lewis and Clark Resort

43496 Shore Drive, Yankton, SD
The price is €112 per night from May 22 to May 23
€112
per night
22 May - 23 May
8.6/10 Excellent! (159 reviews)

Near an Attraction

Santee hotels information

Number of reviews
159
Accommodation
55 hotels
Lowest Price
€112
Highest Price
€112

Frequently asked questions

Where is the best place for a stay in Santee?

Lewis and Clark Resort, located 16.8 mi (27 km) from the heart of Santee, is a top choice for your stay, based on our traveller data. 1916 renovated 8 bedroom, family-friendly home with great views is another good choice for your trip to the area. See all available top hotels, or vacation rentals in Santee.

What are some of the best holiday rentals that Santee has to offer?

Bear Historic Home: This holiday home rental outside Santee is located on a river, and has a fireplace, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. See all vacation rentals in Santee.

If I need to cancel my hotel reservation in Santee, will I receive a refund?

Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.

What are some hotels with pools in Santee?

Lewis and Clark Resort: Features free self-parking, an outdoor pool and free WiFi. View all hotels with pools in Santee.

What is staying in Santee like?

Those travelling to Santee will definitely enjoy the sights to see and things to do. There are 52 hotels and other accommodation options in the surrounding area. Find out more about Santee.

What is there to see in Santee?

A favourite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Lewis and Clark Recreation Area in the area. Take a look at what more there is to see and do in Expedia's Santee guide.

What's the seasonal weather in Santee?

The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -3°C. The snowiest months in Santee are January, December, October and March, with each month seeing an average of 20 cm of snowfall.