Santee Hotels

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
22 Jan - 23 Jan
Tomorrow
23 Jan - 24 Jan
This weekend
23 Jan - 25 Jan
Next weekend
30 Jan - 1 Feb

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Santee hotels

Family House, 4 Bedrooms, Lake View, Lakeside | Living area

Lewis and Clark Resort

Lewis and Clark Resort
2.5 star property
Yankton
8.8 out of 10, Excellent, (287 reviews)
"Beautiful view, easy check in, and spacious accommodations! We loved our stay and can’t wait to come back!"
United States
Jessica
The price is €85
includes taxes & fees
26 Jan - 27 Jan
Lewis and Clark Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Santee Hotel Reviews

Lewis and Clark Resort

Lewis and Clark Resort

10/10 Excellent
"Clean, full kitchen "
Jacquelynn 1-night trip
Posted 1 month ago
Lewis and Clark Resort

More cheap stays in Santee

Lewis and Clark Resort

Lewis and Clark Resort

43496 Shore Drive Yankton SD
The price is €85 per night from 26 Jan to 27 Jan
€85
26 Jan - 27 Jan
includes taxes & fees
8.8/10 Excellent! (287 reviews)

Frequently asked questions

What are some of the best holiday rentals that Santee has to offer?
Modern Lewis and Clark lake home with lake views and 3 min drive to the beach!: This holiday home rental outside of Santee is located near skiing, and has a patio, a garden and air conditioning to put you at ease in your new surroundings. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most hotel reservations are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, it may still be possible to cancel it and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What is staying in Santee like?
Those travelling to Santee will definitely enjoy the sights to see and things to do. There are 64 hotels and other accommodation options in the surrounding area. Find out more about Santee.
What is there to see in Santee?
A favourite place to visit is Lewis and Clark Lake. You'll also find Niobrara State Park and Springfield Recreation Area in the area. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather in Santee?
The hottest months are usually July and August, with an average temperature of 22°C, while the coldest months are January and February, with an average of -3°C. The snowiest months in Santee are January, December, October and March, with each month seeing an average of 20 cm of snowfall.