A riverside promenade with cafes, trees, and buildings.

Santo Antonio Hotel Guide - Luxury Hotels in Santo Antonio, Lisbon District

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Check availability on Santo Antonio Luxury Hotels

Tonight
24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
Next weekend
30 Oct - 1 Nov
In two weeks
6 Nov - 8 Nov

Our top choices for Santo Antonio luxury hotels

1. Valverde Lisboa Hotel & Garden - Relais & Châteaux

Valverde Lisboa Hotel & Garden - Relais & Châteaux
Lisbon City Center
  • Unwind in art deco elegance at this luxury Lisbon hotel with outdoor pool and garden oasis.
€458
includes taxes & fees
16 Nov - 17 Nov
Valverde Lisboa Hotel & Garden - Relais & Châteaux

2. Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
Lisbon City Center
  • Indulge in five-star elegance at this Lisbon hotel where a full-service spa offers aromatherapy treatments steps from Avenida da Liberdade.
€340
includes taxes & fees
6 Nov - 7 Nov
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

3. Memmo Príncipe Real - Design Hotels

Memmo Príncipe Real - Design Hotels
Lisbon City Center
  • Indulge in rooftop luxury at this Lisbon hotel, where designer rooms with city views create an elegant retreat in Principe Real.
€323
includes taxes & fees
19 Nov - 20 Nov
Memmo Príncipe Real - Design Hotels

4. EPIC SANA Marques Hotel

EPIC SANA Marques Hotel
Lisbon City Center
  • Lavish urban retreat with rooftop oasis offers full spa and select comfort beds in Lisbon.
€229
includes taxes & fees
1 Nov - 2 Nov
EPIC SANA Marques Hotel

5. 138 Liberdade Hotel

138 Liberdade Hotel
Lisbon City Center
  • Elevated city escapes await at this 5-star Lisbon hotel, where luxury meets prime location just steps from Avenida da Liberdade.
€251
includes taxes & fees
22 Nov - 23 Nov
138 Liberdade Hotel

6. Sofitel Lisbon Liberdade

Sofitel Lisbon Liberdade
Lisbon City Center
  • Indulge in a luxurious Lisbon stay with a private winery, champagne service, and Portuguese dining in a prime city centre location.
€228
includes taxes & fees
6 Nov - 7 Nov
Sofitel Lisbon Liberdade

7. The Vintage Hotel & Spa - Lisbon

The Vintage Hotel & Spa - Lisbon
Lisbon City Center
  • Indulge in refined comfort at this Lisbon sanctuary where spa treatments, rooftop relaxation, and art deco elegance await.
€268
includes taxes & fees
22 Nov - 23 Nov
The Vintage Hotel & Spa - Lisbon

8. Altis Grand Hotel

Altis Grand Hotel
Lisbon City Center
  • Immerse in 5-star luxury at this Lisbon City Centre hotel featuring a full-service spa, indoor pool, and rooftop terrace.
€212
includes taxes & fees
23 Nov - 24 Nov
Altis Grand Hotel

9. PortoBay Liberdade

PortoBay Liberdade
Lisbon City Center
  • Opulent retreat in the heart of Lisbon offers art deco elegance, rejuvenating spa treatments, and sophisticated dining experiences.
€204
includes taxes & fees
22 Nov - 23 Nov
PortoBay Liberdade

10. Olivia Lisboa Hotel 5*

Olivia Lisboa Hotel 5*
Lisbon City Center
€188
includes taxes & fees
27 Oct - 28 Oct
Olivia Lisboa Hotel 5*
View all properties

Top Santo Antonio Hotel Reviews

BessaHotel Liberdade

BessaHotel Liberdade

10/10 Excellent
"Great boutique style hotel, beautiful decor, friendly staff, excellent location."
Joyce 7-night trip
Posted 4 hours ago
BessaHotel Liberdade
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

10/10 Excellent
"Make sure breakfast is included. Otherwise it is outrageously expensive!"
Timothy 1-night trip
Posted 1 day ago
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
EPIC SANA Marques Hotel

EPIC SANA Marques Hotel

10/10 Excellent
"Amazing service from the moment we arrived from the bellman to reception and housekeeping as well. The hotel’s pool has amazing city and ocean views. Centrally located made getting around quite easy. Would definitely stay here again."
Camillo 2-night trip
Posted 2 days ago
EPIC SANA Marques Hotel
SANA Capitol Hotel

SANA Capitol Hotel

10/10 Excellent
"Absolute perfection – Hands down the BEST breakfast! I had a wonderful stay at this hotel! Everything was excellent, but I have to put a massive emphasis on their breakfast—it was truly top-notch and easily one of the absolute highlights of the stay. I cannot emphasize enough just how incredible the breakfast was every single morning! A huge part of what made breakfast so special was the staff. The team working the breakfast service was beyond amazing—so friendly, genuinely warm, and extremely organized. Even during busy morning hours, they kept everything running seamlessly with a smile. As for the hotel itself, the room was remarkably spacious, sparkling clean, and very comfortable. On top of that, the location is unbeatable—super convenient and close to everything you would want to visit. If you are looking for a spot with immaculate cleanliness, spacious rooms, an ideal location, and a top-notch breakfast experience, this hotel is an absolute must-stay!"
Ebrahim Farhani 3-night trip
Posted 2 days ago
SANA Capitol Hotel
Holiday Inn Express and Suites Lisbon Principe Real by IHG

Holiday Inn Express and Suites Lisbon Principe Real by IHG

10/10 Excellent
"Amazing"
Gabriel 4-night trip
Posted 2 days ago
Holiday Inn Express and Suites Lisbon Principe Real by IHG
Sofitel Lisbon Liberdade

Sofitel Lisbon Liberdade

10/10 Excellent
"Had a great stay at this hotel. The front desk staff and concierge were excellent. The bar and restaurant, chef’s kiss!!! I also found time to hit their gym which was clean and efficient."
Derrick 3-night trip
Posted 5 days ago
Sofitel Lisbon Liberdade
Heritage Lisboa Plaza Hotel - Avenida

Heritage Lisboa Plaza Hotel - Avenida

10/10 Excellent
"Absolutely perfect and lovely! Had a wonderful experience!"
Holly 6-night trip
Posted 6 days ago
Heritage Lisboa Plaza Hotel - Avenida

Frequently asked questions

Are you looking for a luxury hotel for your Santo Antonio holiday?
Travel to Lisbon (LIS-Humberto Delgado) Airport or Cascais (CAT) Airport, and then treat yourself to a stay at one of 18 Santo Antonio luxury hotels. Known for its spas and art, Santo Antonio also has some interesting things to see and do including Avenida da Liberdade, so you may want to take in the local sights during your visit.
What's the best luxury hotel in Santo Antonio?
Olivia Lisboa Hotel 5* is a luxury hotel with a restaurant, and a popular choice for Expedia travellers looking for an elegant place to stay. EPIC SANA Lisboa Hotel and EPIC SANA Marques Hotel are other upscale choices for your holiday.
How many luxury hotels should I expect to find in Santo Antonio?
Lie in the lap of luxury during your getaway to Santo Antonio in one of Expedia's 18 luxury hotels.
When can I expect good weather in Santo Antonio?
Planning for the weather is an important factor for making your trip to Santo Antonio a success, especially when you're splurging. The hottest months are usually August and July, with an average temperature of 21°C, while the coldest months are February and January, with an average of 13°C. Average annual precipitation for Santo Antonio is 573 mm.
What's there to see and do in Santo Antonio?
When you're in Santo Antonio, enjoy exploring the sights and attractions here including Avenida da Liberdade, Cinemateca Portuguesa Museum and Marquis of Pombal Square. If you have extra time while you're in the area, you might want to stop by Medeiros e Almeida Museum and Coracao de Jesus.
How can I get around Santo Antonio?
It's easier to get around town in style when you know your options. You can walk to nearby metro stations including Avenida Station, Marques de Pombal Station and Rato Station.