Santo Antonio Holidays

  • Plan, book, travel with confidence

  • Better together

    Save up to €900 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Top Flight + Hotel Deals in Santo Antonio

Price found within the past 48 hours. Click for updated prices.
Zero Box Lodge Coimbra

Zero Box Lodge Coimbra

3 out of 5
Coimbra City Centre
Price was €813, price is now €795 per person
€795
per person
1 Sept - 3 Sept
found 1 day ago
Return direct flight included
Dublin (DUB) to Lisbon (LIS)
9/10 Wonderful! (280 reviews)
.

Reviewed on 22 Jul 2026

Top hotels in Santo Antonio

Locke de Santa Joana

Locke de Santa Joana

4 out of 5
18 Rua Camilo Castelo Branco Lisbon
Fully refundableReserve now, pay when you stay
The price is €139 per night from 12 Aug to 13 Aug
€139
12 Aug - 13 Aug
includes taxes & fees
9.4/10 Exceptional! (1,951 reviews)
"Amazing hotel in the best location. Hotel itself is beautiful, staff was very helpful, professional and so pleasant"

Reviewed on 25 Jul 2026

Locke de Santa Joana
Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world

5 out of 5
Avenida Liberdade, 185 Lisbon
Fully refundableReserve now, pay when you stay
The price is €344 per night from 12 Aug to 13 Aug
€344
12 Aug - 13 Aug
includes taxes & fees
9/10 Wonderful! (1,005 reviews)
"The service and rooms were impeccable."

Reviewed on 24 Jul 2026

Tivoli Avenida Liberdade Lisboa – A Leading hotel of the world
EPIC SANA Lisboa Hotel

EPIC SANA Lisboa Hotel

5 out of 5
Av. Engenheiro Duarte Pacheco 15 Lisbon
Fully refundableReserve now, pay when you stay
The price is €196 per night from 8 Aug to 9 Aug
€196
8 Aug - 9 Aug
includes taxes & fees
9.6/10 Exceptional! (1,072 reviews)
"I had a great experience, the staff and environment was great. My friend and I felt really safe (2 girls in their 20s). It’s in the center of everything and it’s walkable."

Reviewed on 24 Jul 2026

EPIC SANA Lisboa Hotel
See all 682 properties in Santo Antonio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santo Antonio attractions

A historic building with a dome and a Louis Vuitton store.

Avenida da Liberdade

9.4/10 (3,467 reviews)
You can find the perfect gifts to bring home when you visit Avenida da Liberdade, a popular shopping spot in Santo Antonio. Discover the charming cafes in this family-friendly area or seek out the local tours.
See properties

What to do in Santo Antonio

Lisbon Card

Lisbon Card

€31
per adult
86% of travellers recommend
Lisbon Card
Castle in Lisbon

Day Trip to Sintra & Cascais with Admission to Pena Palace and Garden Walk

€80
per adult
96% of travellers recommend
Day Trip to Sintra & Cascais with Admission to Pena Palace and Garden Walk
Hop-On Hop-Off Boat Tour with Optional Bus Tour Combos

Lisbon Hop-On Hop-Off Packs

€28
per adult
Lisbon Hop-On Hop-Off Packs
See all activities in Santo Antonio

Frequently asked questions

What are the cheapest months to go to Santo Antonio?
December, January and February are the best times to look for cheap Santo Antonio holiday packages. Opting to travel in less busy months means you can usually find lower prices on flights and hotels.
How many days is enough for Santo Antonio?
Generally, a handful of days is enough to visit the major sights during your Santo Antonio holiday. But if you want to have some time to rest or go on day trips, consider extending your itinerary.
Is it worth booking a holiday package to Santo Antonio?
Well known for its shopping, cafes and culture, a Santo Antonio holiday is a hit with all kinds of visitors. Be sure to visit main sights like Medeiros e Almeida Museum and Cinemateca Portuguesa Museum, and consider renting a set of wheels for day trips to discover even more.
How to find the best Santo Antonio package deals?
Bagging a cheap Santo Antonio package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, add some filters and browse what's available. You can tailor your search by "Amenities," "Property type," "Traveller experience" and more. Sort the results by "Price: low to high" to view the most wallet-friendly Santo Antonio package deals. Want a simple trick to get even more savings? Be flexible with your departure dates and consider going away on a weekday, when prices are often lower.
When to book a holiday package to Santo Antonio?
If you're considering a spontaneous Santo Antonio adventure, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land incredible deals on your flights and hotels by booking well in advance.
How to plan a trip to Santo Antonio?

  1. Choose your travel dates: What you'd like to do in Santo Antonio and your favourite season will help you decide when to get away.
  2. Set your budget: Factor in expenses like food, flights and transportation when working out how much to put aside for your trip to Santo Antonio. Then, select a hotel that suits your budget, whether that's a low-cost option or a swankier retreat.
  3. Decide how many days away: Start by compiling a list of the activities and attractions you want to get to in Santo Antonio. Then, estimate how long you'll need for each, including any travel time.
  4. Bundle your bookings: With your travel dates in place, you can combine your hotels, flights, car rental and more into a customised Santo Antonio holiday package.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.