Santo Domingo Holidays

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    Save up to €900 when you book a flight and hotel together*

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    With over 300,000 hotels worldwide, it's easy to create a perfect package

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Top hotels in Santo Domingo

The Brown, Guatape, Autograph Collection

The Brown, Guatape, Autograph Collection

4 out of 5
El Peñol - Guatape Paraje Guatapé Antioquia
Fully refundableReserve now, pay when you stay
The price is €236 per night from 12 Aug to 13 Aug
€236
12 Aug - 13 Aug
The Brown, Guatape, Autograph Collection
Hotel Los Recuerdos

Hotel Los Recuerdos

3.5 out of 5
Via Peñol Gatapé Km 19 Guatapé Antioquia
Fully refundableReserve now, pay when you stay
The price is €102 per night from 29 Jul to 30 Jul
€102
29 Jul - 30 Jul
8.2/10 Very good! (666 reviews)
"Amazing location, amazing staff. During the week is less crowded and therefore feels more peaceful!"

Reviewed on 27 Jul 2026

Hotel Los Recuerdos
Vivanti Resort

Vivanti Resort

3.5 out of 5
Vereda Uvital 76-20 El Peñol Antioquia
Fully refundable
The price is €144 per night from 3 Aug to 4 Aug
€144
3 Aug - 4 Aug
9/10 Wonderful! (36 reviews)
"Lonely, boutique hotel bedside a beautiful and active lake."

Reviewed on 14 Jul 2026

Vivanti Resort
See all 591 properties in Santo Domingo
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santo Domingo

Route of the 7 Pools: 1 hour from Medellín

Route of the 7 Pools: 1 hour from Medellín

€41
per adult
Route of the 7 Pools: 1 hour from Medellín
We were blessed with more than 70 different fruits growing in San Rafael Town

Flavors of Colombia through Cocoa Coffee and Sugarcane Panela

€35
per adult
Flavors of Colombia through Cocoa Coffee and Sugarcane Panela
Medellín: Magical Tubing Río Arenal San Rafael

Medellín: Magical Tubing Río Arenal San Rafael

€37
per adult
Medellín: Magical Tubing Río Arenal San Rafael
See all activities in Santo Domingo

Frequently asked questions

How much does a Santo Domingo holiday package cost?
You can grab a holiday package to this destination on Expedia. But how much your holiday to Santo Domingo costs will depend on the length of stay, hotel choice and season.
What are the cheapest months to go to Santo Domingo?
April, June and September are the best times to search for cheap Santo Domingo holiday packages. Opting to travel in quieter periods means you can typically find reduced prices on accommodation and flights.
How many days is enough for Santo Domingo?
Typically, a handful of days is enough to tick off the main attractions during your Santo Domingo holiday. However, if you prefer to have some time to relax or go on day trips, consider extending your trip.
How to find the best Santo Domingo package deals?
Landing a cheap Santo Domingo package deal is a breeze with Expedia. After you've entered your destination and preferred dates under our "Packages" tab, set your budget, add a few filters and see what's available. You can tweak your search by "Amenities," "Property type," "Popular locations" and more. Order the results by "Price: low to high" to view the most economical Santo Domingo package deals. Want a simple trick to get the biggest savings? Be flexible with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santo Domingo holiday as a package?
An Expedia holiday package could land you considerable savings when compared to booking flights and hotels individually. Better still, you can personalise your Santo Domingo escape to match your exact needs. Choose your preferred flight time, select the hotel type and add a car rental. Check out our great deals to see how much you can save.
When to book a holiday package to Santo Domingo?
If you're considering a spontaneous Santo Domingo getaway, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land incredible deals on your hotels and flights by booking well in advance.
How to plan a trip to Santo Domingo?

  1. Pick the ideal time to travel: Your schedule, favourite season and the type of weather you enjoy can all influence your decision on when to visit Santo Domingo.
  2. Figure out your budget: Ensure you have enough money to cover everything from transportation and dining out to flights and experiences. Your accommodation will likely be the largest expense during your trip to Santo Domingo.
  3. Determine how many days away: Start by listing all the activities and sights you'd like to get to in Santo Domingo. Then, estimate how long you'll need at each, as well as any travel time.
  4. Combine your accommodation and airfare: After you've nailed down your travel dates and duration, lock in the perfect Santo Domingo holiday package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.